Saha, Shekhar, Joskowiak, Dominik, Marin-Cuartas, Mateo ORCID: 0000-0003-1000-4710, Diab, Mahmoud, Schwaiger, Benedikt M., Sandoval-Boburg, Rodrigo, Popov, Aron-Frederik, Weber, Carolyn, Varghese, Sam, Martens, Andreas ORCID: 0000-0002-7953-2645, Cebotari, Serghei, Scherner, Maximilian, Eichinger, Walter, Holzhey, David, Dohle, Daniel-Sebastian ORCID: 0000-0001-7172-2658, Wahlers, Thorsten, Doenst, Torsten, Misfeld, Martin, Mehilli, Julinda, Massberg, Steffen and Hagl, Christian (2022). Surgery for infective endocarditis following low-intermediate risk transcatheter aortic valve replacement-a multicentre experience. Eur. J. Cardio-Thorac. Surg., 62 (1). CARY: OXFORD UNIV PRESS INC. ISSN 1873-734X

Full text not available from this repository.

Abstract

OBJECTIVES With the expansion of transcatheter aortic valve replacement (TAVR) into intermediate and low risk, the number of TAVR procedures is bound to rise and along with it the number of cases of infective endocarditis following TAVR (TIE). The aim of this study was to review a multicentre experience of patients undergoing surgical intervention for TIE and to analyse the underlying indications and operative results. METHODS We retrospectively identified and analysed 69 patients who underwent cardiac surgery due to TIE at 9 cardiac surgical departments across Germany. The primary outcome was operative mortality, 6-month and 1-year survival. RESULTS Median age was 78 years (72-81) and 48(69.6%) were male. The median time to surgical aortic valve replacement was 14 months (5-24) after TAVR, with 32 patients (46.4%) being diagnosed with early TIE. Cardiac reoperations were performed in 17% of patients and 33% underwent concomitant mitral valve surgery. The main causative organisms were: Enterococcus faecalis (31.9%), coagulase-negative Staphylococcus spp. (26.1%), Methicillin-sensitive Staphylococcus aureus (15.9%) and viridians group streptococci (14.5%). Extracorporeal life support was required in 2 patients (2.9%) for a median duration of 3 days. Postoperative adverse cerebrovascular events were observed in 13 patients (18.9%). Postoperatively, 9 patients (13.0%) required a pacemaker and 33 patients (47.8%) needed temporary renal replacement therapy. Survival to discharge was 88.4% and survival at 6 months and 1 year was found to be 68% and 53%, respectively. CONCLUSIONS Our results suggest that TIE can be treated according to the guidelines for prosthetic valve endocarditis, namely with early surgery. Surgery for TIE is associated with acceptable morbidity and mortality rates. Surgery should be discussed liberally as a treatment option in patients with TIE by the 'endocarditis team' in referral centres.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Saha, ShekharUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Joskowiak, DominikUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Marin-Cuartas, MateoUNSPECIFIEDorcid.org/0000-0003-1000-4710UNSPECIFIED
Diab, MahmoudUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schwaiger, Benedikt M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sandoval-Boburg, RodrigoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Popov, Aron-FrederikUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Weber, CarolynUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Varghese, SamUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Martens, AndreasUNSPECIFIEDorcid.org/0000-0002-7953-2645UNSPECIFIED
Cebotari, SergheiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Scherner, MaximilianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Eichinger, WalterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Holzhey, DavidUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dohle, Daniel-SebastianUNSPECIFIEDorcid.org/0000-0001-7172-2658UNSPECIFIED
Wahlers, ThorstenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Doenst, TorstenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Misfeld, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mehilli, JulindaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Massberg, SteffenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hagl, ChristianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-693999
DOI: 10.1093/ejcts/ezac075
Journal or Publication Title: Eur. J. Cardio-Thorac. Surg.
Volume: 62
Number: 1
Date: 2022
Publisher: OXFORD UNIV PRESS INC
Place of Publication: CARY
ISSN: 1873-734X
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
IMPLANTATION; DIAGNOSIS; OUTCOMES; TAVRMultiple languages
Cardiac & Cardiovascular Systems; Respiratory System; SurgeryMultiple languages
URI: http://kups.ub.uni-koeln.de/id/eprint/69399

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item