Universität zu Köln

Lüke, Jan Niklas ORCID: 0000-0001-7131-7652, Lüke, Vincent, Dietlein, Thomas ORCID: 0009-0007-4841-6397, Wiedemann, Johanna ORCID: 0009-0000-0496-4921 and Lappas, Alexandra (2025). Preliminary Short-Term Results of Supraciliary Ab-Interno MINIject® Implantation Following Failed Filtering Glaucoma Surgery in Primary Open-Angle Glaucoma. Clinical Ophthalmology, 19. pp. 3227-3235. Dovepress Taylor & Francis Group. ISSN 1177-5467

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Abstract

Purpose: To investigate the efficacy of MINIject ® (suprachoroidal stent) in lowering intraocular pressure (IOP) in eyes following failed filtering glaucoma surgery. Methods: In this single-center retrospective study, 18 patients who had undergone suprachoroidal stent implantation after failed filtering surgery were analyzed. Follow-up was at least 12 months, and surgical success was measured by 12-month postoperative intraocular pressure (IOP), glaucoma medication, and revision surgery (criteria A: IOP < 21 mmHg, IOP reduction >20%, no revision surgery; criteria B: IOP < 18 mmHg, IOP reduction >20%, no revision surgery; criteria C: IOP ≤ 15 mmHg, IOP reduction ≥40%, no repeat surgery). Results: After a follow-up period of 12 months, the mean IOP decreased from 27.11±5.65 mmHg to 15.94±9.56 mmHg (p<0.01). The median 12-month postoperative IOP was 14.0 mmHg (IQR: 10.0–20.0 mmHg). The probability of surgical success was 66.66% for criteria A and B and 50% for criteria C. The identical success rates for criteria A and B were due to overlapping responder groups in this limited sample. Topical medication was significantly reduced from 4.06±1.08 to 2.13±1.36 (p<0.0001). Conclusion: Supraciliary stent implantation provided an effective and safe treatment option for advanced glaucoma following failed filtering surgery and demonstrated significant intraocular pressure reduction. However, the small sample size limits the generalizability of these findings.

Item Type:	Article
Creators:	Creators Email ORCID ORCID Put Code Lüke, Jan Niklas UNSPECIFIED https://orcid.org/0000-0001-7131-7652 UNSPECIFIED Lüke, Vincent UNSPECIFIED UNSPECIFIED UNSPECIFIED Dietlein, Thomas UNSPECIFIED https://orcid.org/0009-0007-4841-6397 UNSPECIFIED Wiedemann, Johanna UNSPECIFIED https://orcid.org/0009-0000-0496-4921 UNSPECIFIED Lappas, Alexandra UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-798570
Identification Number:	10.2147/OPTH.S534745
Journal or Publication Title:	Clinical Ophthalmology
Volume:	19
Page Range:	pp. 3227-3235
Number of Pages:	9
Date:	4 September 2025
Publisher:	Dovepress Taylor & Francis Group
ISSN:	1177-5467
Language:	English
Faculty:	Faculty of Medicine
Divisions:	Faculty of Medicine > Augenheilkunde > Klinik und Poliklinik für Allgemeine Augenheilkunde
Subjects:	Medical sciences Medicine
['eprint_fieldname_oa_funders' not defined]:	Publikationsfonds UzK
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/79857