Universität zu Köln

Faber, Julian ORCID: 0000-0002-1435-9343, Schuster, Frank, Hartmann, Stefan, Brands, Roman C., Fuchs, Andreas, Straub, Anton, Fischer, Markus, Müller-Richter, Urs and Linz, Christian ORCID: 0000-0002-1155-8478 (2024). Successful microvascular surgery in patients with thrombophilia in head and neck surgery: a case series. Journal of Medical Case Reports, 18 (1). pp. 1-7. Springer Nature. ISSN 1752-1947

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Abstract

[Artikel-Nr.: 119] Background: In this case series, a perioperative anticoagulation protocol for microvascular head and neck surgery in patients with thrombophilia is presented. Microvascular free-flap surgery is a standard procedure in head and neck surgery with high success rates. Nevertheless, flap loss—which is most often caused by thrombosis—can occur and has far-reaching consequences, such as functional impairment, prolonged hospitalization, and increased costs. The risk of flap loss owing to thrombosis is significantly increased in patients with thrombophilia. Therefore, perioperative anticoagulation is mandatory. To date, no perioperative anticoagulation protocol exists for these high-risk patients. Case presentation: We present three exemplary male Caucasian patients aged 53–57 years with free flap loss owing to an underlying, hidden thrombophilia. Conclusion: We present a modified anticoagulation protocol for microvascular surgery in these high-risk patients, enabling successful microsurgical reconstruction.

Item Type:	Article
Creators:	Creators Email ORCID ORCID Put Code Faber, Julian UNSPECIFIED https://orcid.org/0000-0002-1435-9343 UNSPECIFIED Schuster, Frank UNSPECIFIED UNSPECIFIED UNSPECIFIED Hartmann, Stefan UNSPECIFIED UNSPECIFIED UNSPECIFIED Brands, Roman C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Fuchs, Andreas UNSPECIFIED UNSPECIFIED UNSPECIFIED Straub, Anton UNSPECIFIED UNSPECIFIED UNSPECIFIED Fischer, Markus UNSPECIFIED UNSPECIFIED UNSPECIFIED Müller-Richter, Urs UNSPECIFIED UNSPECIFIED UNSPECIFIED Linz, Christian UNSPECIFIED https://orcid.org/0000-0002-1155-8478 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-815175
Identification Number:	10.1186/s13256-024-04403-8
Journal or Publication Title:	Journal of Medical Case Reports
Volume:	18
Number:	1
Page Range:	pp. 1-7
Number of Pages:	7
Date:	28 February 2024
Publisher:	Springer Nature
ISSN:	1752-1947
Language:	English
Faculty:	Faculty of Medicine
Divisions:	Faculty of Medicine > Zahn-, Mund- und Kieferheilkunde > Klinik und Poliklinik für Mund-, Kiefer- und Plastische Gesichtschirurgie und Interdisziplinäre Klinik für Orale Chirurgie und Implantologie
Subjects:	Medical sciences Medicine
Uncontrolled Keywords:	Keywords Language Thrombophilia ; Microvascular surgery ; Free flap ; Anticoagulation ; Factor V Leiden mutation ; Head and neck, Case report English
['eprint_fieldname_oa_funders' not defined]:	Publikationsfonds UzK
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/81517