Universität zu Köln

Derendorf, Lisa ORCID: 0000-0003-0213-9471, Stock, Stephanie ORCID: 0000-0002-1726-9300, Simic, Dusan ORCID: 0000-0002-7325-9481, Shukri, Arim ORCID: 0000-0003-3709-3493, Zelenak, Christine ORCID: 0000-0002-2922-2278, Nagel, Jonas ORCID: 0000-0001-5900-1188, Friede, Tim ORCID: 0000-0001-5347-7441, Herbeck Belnap, Birgit ORCID: 0000-0001-6572-9896, Herrmann-Lingen, Christoph ORCID: 0000-0002-7813-7045, Pedersen, Susanne S. ORCID: 0000-0001-8055-3251, Sørensen, Jan and Müller and on behalf of the ESCAPE, Dirk ORCID: 0000-0002-5576-0192 (2024). Health economic evaluation of blended collaborative care for older multimorbid heart failure patients: study protocol. Cost Effectiveness and Resource Allocation, 22 (1). pp. 1-9. Springer Nature. ISSN 1478-7547

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Abstract

[Artikel-Nr.: 29] Background: Integrated care, in particular the ‘Blended Collaborative Care (BCC)’ strategy, may have the potential to improve health-related quality of life (HRQoL) in multimorbid patients with heart failure (HF) and psychosocial burden at no or low additional cost. The ESCAPE trial is a randomised controlled trial for the evaluation of a BCC approach in five European countries. For the economic evaluation of alongside this trial, the four main objectives were: (i) to document the costs of delivering the intervention, (ii) to assess the running costs across study sites, (iii) to evaluate short-term cost-effectiveness and cost-utility compared to providers’ usual care, and (iv) to examine the budgetary implications. Methods: The trial-based economic analyses will include cross-country cost-effectiveness and cost-utility assessments from a payer perspective. The cost-utility analysis will calculate quality-adjusted life years (QALYs) using the EQ-5D-5L and national value sets. Cost-effectiveness will include the cost per hospital admission avoided and the cost per depression-free days (DFD). Resource use will be measured from different sources, including electronic medical health records, standardised questionnaires, patient receipts and a care manager survey. Uncertainty will be addressed using bootstrapping. Discussion: The various methods and approaches used for data acquisition should provide insights into the potential benefits and cost-effectiveness of a BCC intervention. Providing the economic evaluation of ESCAPE will contribute to a country-based structural and organisational planning of BCC (e.g., the number of patients that may benefit, how many care managers are needed). Improved care is expected to enhance health-related quality of life at little or no extra cost. Trial registration: The study follows CHEERS2022 and is registered at the German Clinical Trials Register (DRKS00025120).

Item Type:	Article
Creators:	Creators Email ORCID ORCID Put Code Derendorf, Lisa UNSPECIFIED https://orcid.org/0000-0003-0213-9471 UNSPECIFIED Stock, Stephanie UNSPECIFIED https://orcid.org/0000-0002-1726-9300 UNSPECIFIED Simic, Dusan UNSPECIFIED https://orcid.org/0000-0002-7325-9481 UNSPECIFIED Shukri, Arim UNSPECIFIED https://orcid.org/0000-0003-3709-3493 UNSPECIFIED Zelenak, Christine UNSPECIFIED https://orcid.org/0000-0002-2922-2278 UNSPECIFIED Nagel, Jonas UNSPECIFIED https://orcid.org/0000-0001-5900-1188 UNSPECIFIED Friede, Tim UNSPECIFIED https://orcid.org/0000-0001-5347-7441 UNSPECIFIED Herbeck Belnap, Birgit UNSPECIFIED https://orcid.org/0000-0001-6572-9896 UNSPECIFIED Herrmann-Lingen, Christoph UNSPECIFIED https://orcid.org/0000-0002-7813-7045 UNSPECIFIED Pedersen, Susanne S. UNSPECIFIED https://orcid.org/0000-0001-8055-3251 UNSPECIFIED Sørensen, Jan UNSPECIFIED UNSPECIFIED UNSPECIFIED Müller and on behalf of the ESCAPE, Dirk UNSPECIFIED https://orcid.org/0000-0002-5576-0192 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-815361
Identification Number:	10.1186/s12962-024-00535-2
Journal or Publication Title:	Cost Effectiveness and Resource Allocation
Volume:	22
Number:	1
Page Range:	pp. 1-9
Number of Pages:	9
Date:	13 April 2024
Publisher:	Springer Nature
ISSN:	1478-7547
Language:	English
Faculty:	Faculty of Medicine
Divisions:	Faculty of Medicine > Gesundheitsökonomie > Institut für Gesundheitsökonomie und Klinische Epidemiologie
Subjects:	Medical sciences Medicine
Uncontrolled Keywords:	Keywords Language Health economic evaluation ; Cost-effectiveness ; Cost-utility ; Heart failure ; Multimorbidity ; Collaborative care ; Time-driven activity-based costing ; Depression ; Emotional distress ; Elderly English
['eprint_fieldname_oa_funders' not defined]:	Publikationsfonds UzK
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/81536