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Number of items: 45.

Journal Article

Al-Batran, Salah-Eddin, Goetze, Thorsten O., Mueller, Daniel W., Vogel, Arndt, Winkler, Michael, Lorenzen, Sylvie, Novotny, Alexander, Pauligk, Claudia, Homann, Nils, Jungbluth, Thomas, Reissfelder, Christoph ORCID: 0000-0003-4591-1046, Caca, Karel, Retter, Steffen, Horndasch, Eva, Gumpp, Julia, Bolling, Claus, Fuchs, Karl-Hermann, Blau, Wolfgang, Padberg, Winfried, Pohl, Michael, Wunsch, Andreas, Michl, Patrick, Mannes, Frank, Schwarzbach, Matthias, Schmalenberg, Harald, Hohaus, Michael, Scholz, Christian, Benckert, Christoph, Knorrenschild, Jorge Riera, Kanngiesser, Veit, Zander, Thomas, Alakus, Hakan, Hofheinz, Ralf-Dieter, Roedel, Claus, Shah, Manish A., Sasako, Mitsuru, Lorenz, Dietmar, Izbicki, Jakob, Bechstein, Wolf O., Lang, Hauke and Moenig, Stefan P. (2017). The RENAISSANCE (AIO-FLOT5) trial: effect of chemotherapy alone vs. chemotherapy followed by surgical resection on survival and quality of life in patients with limited-metastatic adenocarcinoma of the stomach or esophagogastric junction - a phase III trial of the German AIO/CAO-V/CAOGI. BMC Cancer, 17. LONDON: BIOMED CENTRAL LTD. ISSN 1471-2407

Alakus, Hakan and Bruns, Christiane (2018). FGFR inhibition in cholangiocarcinoma. Onkologe, 24 (5). S. 425 - 427. NEW YORK: SPRINGER. ISSN 1433-0415

Alakus, Hakan and Bruns, Christiane (2018). Pembrolizumab for advanced esophageal carcinoma. Onkologe, 24 (1). S. 76 - 79. NEW YORK: SPRINGER. ISSN 1433-0415

Alakus, Hakan and Bruns, Christiane (2017). Time between neoadjuvant radiochemotherapy and rectum resection. Onkologe, 23 (2). S. 146 - 149. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-0415

Alakus, Hakan and Bruns, Christiane (2017). Timing of chemotherapy and survival in gastric cancer. Onkologe, 23 (10). S. 856 - 858. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-0415

Alakus, Hakan and Bruns, Christiane J. (2016). Weekday of Esophagectomy and Prognosis. Onkologe, 22 (9). S. 690 - 692. NEW YORK: SPRINGER. ISSN 1433-0415

Alakus, Hakan, Kuetting, Fabian and Bruns, Christiane (2018). Cabozantinib for advanced hepatocellular Carcinoma. Onkologe, 24 (11). S. 924 - 927. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-0415

Alakus, Hakan, Zander, Thomas and Bruns, Christiane (2018). Nivolumab and Ipilimumab in Renal Cell Carcinoma. Onkologe, 24 (6). S. 500 - 505. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-0415

Alakus, Hakan, Zander, Thomas and Bruns, Christiane (2018). Osimertinib for non-small-cell Lung Cancer. Onkologe, 24 (2). S. 174 - 177. NEW YORK: SPRINGER. ISSN 1433-0415

Berlth, Felix, Bludau, Marc, Plum, Patrick Sven, Herbold, Till, Christ, Hildegard ORCID: 0000-0003-3235-2994, Alakus, Hakan, Kleinert, Robert, Bruns, Christiane Josephine, Hoelscher, Arnulf Heinrich and Chon, Seung-Hun ORCID: 0000-0002-8923-6428 (2019). Self-Expanding Metal Stents Versus Endoscopic Vacuum Therapy in Anastomotic Leak Treatment After Oncologic Gastroesophageal Surgery. J. Gastrointest. Surg., 23 (1). S. 67 - 76. NEW YORK: SPRINGER. ISSN 1873-4626

Bludau, Marc ORCID: 0000-0002-0338-1545, Fuchs, Hans F., Herbold, Till, Maus, Martin K. H., Alakus, Hakan, Popp, Felix, Leers, Jessica M., Bruns, Christiane J., Hoelscher, Arnulf H., Schroeder, Wolfgang and Chon, Seung-Hun ORCID: 0000-0002-8923-6428 (2018). Results of endoscopic vacuum-assisted closure device for treatment of upper GI leaks. Surg. Endosc., 32 (4). S. 1906 - 1915. NEW YORK: SPRINGER. ISSN 1432-2218

Bollschweiler, Elfriede, Hoelscher, Arnulf H., Herbold, Till, Metzger, Ralf, Alakus, Hakan, Schmidt, Henner, Drebber, Uta and Warnecke-Eberz, Ute (2016). Molecular Markers for the Prediction of Minor Response to Neoadjuvant Chemoradiation in Esophageal Cancer: Results of the Prospective Cologne Esophageal Response Prediction (CERP) Study. Ann. Surg., 264 (5). S. 839 - 847. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1528-1140

Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Berlth, Felix ORCID: 0000-0002-3780-0728, Plum, Patrick Sven, Herbold, Till, Alakus, Hakan, Kleinert, Robert, Moenig, Stefan Paul, Bruns, Christiane Josephine, Hoelscher, Arnulf Heinrich and Meyer, Hans-Joachim (2017). Gastric cancer treatment in the world: Germany. Transl. Gastroenterol. Hepatol., 2. SHEUNG WAN: AME PUBL CO. ISSN 2415-1289

Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Hilgers, Sabrina ORCID: 0000-0002-7896-5078, Timmermann, Ferdinand ORCID: 0000-0002-2210-9459, Dratsch, Thomas, Plum, Patrick Sven, Berlth, Felix ORCID: 0000-0002-3780-0728, Datta, Rabi, Alakus, Hakan, Schloesser, Hans Anton, Schramm, Christoph, dos Santos, Daniel Pinto, Bruns, Christiane and Kleinert, Robert (2018). Web-Based Immersive Patient Simulator as a Curricular Tool for Objective Structured Clinical Examination Preparation in Surgery: Development and Evaluation. JMIR Serious Games, 6 (3). TORONTO: JMIR PUBLICATIONS, INC. ISSN 2291-9279

D' Antonio, Matteo, Weghorn, Donate, D' Antonio-Chronowska, Agnieszka, Coulet, Florence, Olson, Katrina M., DeBoever, Christopher ORCID: 0000-0002-1901-2576, Drees, Frauke, Arias, Angelo, Alakus, Hakan, Richardson, Andrea L., Schwab, Richard B., Farley, Emma K., Sunyaev, Shamil R. and Frazer, Kelly A. (2017). Identifying DNase I hypersensitive sites as driver distal regulatory elements in breast cancer. Nat. Commun., 8. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Duebbers, Martin, Nikolaou, Elena, Fuchs, Hans, Fischer, Janina, Alakus, Hakan, Leers, Jessica, Bruns, Christiane and Cernaianu, Grigore (2018). Update on Transumbilical Single-Incision Laparoscopic Assisted Appendectomy (TULAA) - Which Children Benefit and What are the Complications? Klinische Padiatr., 230 (4). S. 194 - 200. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1439-3824

Eminaga, Okyaz, Fries, Jochen ORCID: 0000-0003-2054-6345, Neiss, Susanne, Heitmann, Michaela, Woetzel, Fabian, Heidenreich, Axel, Bruns, Christiane, Alakus, Hakan and Warnecke-Eberz, Ute (2018). The upregulation of hypoxia-related miRNA 210 in primary tumor of lymphogenic metastatic prostate cancer. Epigenomics, 10 (10). S. 1347 - 1360. LONDON: FUTURE MEDICINE LTD. ISSN 1750-192X

Fuchs, Hans, Hoelscher, Arnulf H., Leers, Jessica, Bludau, Marc, Brinkmann, Sebastian, Schroeder, Wolfgang, Alakus, Hakan, Moenig, Stefan and Gutschow, Christian A. (2016). Long-term quality of life after surgery for adenocarcinoma of the esophagogastric junction: extended gastrectomy or transthoracic esophagectomy? Gastric Cancer, 19 (1). S. 312 - 318. NEW YORK: SPRINGER. ISSN 1436-3305

Gassa, Asmae, Alakus, Hakan and Bruns, Christiane (2018). Detection of Malignant Tumors by means of a Blood Test. Onkologe, 24 (4). S. 340 - 343. NEW YORK: SPRINGER. ISSN 1433-0415

Heinrichs, Sophie K. M., Hess, Timo, Becker, Jessica, Hamann, Lutz, Vashist, Yogesh K., Butterbach, Katja, Schmidt, Thomas ORCID: 0000-0002-7166-3675, Alakus, Hakan, Krasniuk, Iurii, Hoeblinger, Aksana, Lingohr, Philipp, Ludwig, Monika, Hagel, Alexander F., Schildberg, Claus W., Veits, Lothar, Gyvyte, Ugne ORCID: 0000-0002-1130-2472, Weise, Katharina, Schueller, Vitalia, Boehmer, Anne C., Schroeder, Julia, Gehlen, Jan, Kreuser, Nicole, Hofer, Sebastian, Lang, Hauke, Lordick, Florian, Malfertheiner, Peter, Moehler, Markus, Pech, Oliver, Vassos, Nikolaos, Rodermann, Ernst, Izbicki, Jakob R., Kruschewski, Martin, Ott, Katja, Schumann, Ralf R., Vieth, Michael, Mangold, Elisabeth, Gasenko, Evita, Kupcinskas, Limas, Brenner, Hermann, Grimminger, Peter, Bujanda, Luis, Sopena, Federico, Espinel, Jesus, Thomson, Concha, Perez-Aisa, Angeles, Campo, Rafael, Geijo, Fernando, Collette, Daniela, Bruns, Christiane, Messerle, Katharina, Gockel, Ines, Noethen, Markus M., Lippert, Hans, Ridwelski, Karsten, Lanas, Angel, Keller, Gisela, Knapp, Michael, Leja, Marcis, Kupcinskas, Juozas, Garcia-Gonzalez, Maria A., Venerito, Marino ORCID: 0000-0001-8581-0974 and Schumacher, Johannes (2018). Evidence for PTGER4, PSCA, and MBOAT7 as risk genes for gastric cancer on the genome and transcriptome level. Cancer Med., 7 (10). S. 5057 - 5066. HOBOKEN: WILEY. ISSN 2045-7634

Kasper, Philipp ORCID: 0000-0002-6218-2239, Puetz, Katharina, Fuenger, Sarah, Suarez, Isabelle, Jung, Norma, Alakus, Hakan, Bruns, Christiane and Rybniker, Jan (2018). Postoperative granulomatous peritonitis mimicking abdominal tuberculosis. Clin. Case Rep., 6 (9). S. 1810 - 1815. HOBOKEN: WILEY. ISSN 2050-0904

Kuetting, Fabian, Alakus, Hakan and Bruns, Christiane (2018). Cetuximab and FOLFOX-4 in metastasized colorectal Cancer. Onkologe, 24 (12). S. 1034 - 1037. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-0415

Kuetting, Fabian, Bludau, Marc, Alakus, Hakan and Bruns, Christiane (2019). MSI and Tumor Mutational Burden in Colorectal Cancer. Onkologe, 25 (9). S. 829 - 831. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-0415

Loeser, Heike ORCID: 0000-0003-4555-1327, Kraemer, Max, Gebauer, Florian, Bruns, Christiane, Schroeder, Wolfgang, Zander, Thomas, Persa, Oana-Diana, Alakus, Hakan, Hoelscher, Arnulf, Buettner, Reinhard, Lohneis, Philipp and Quaas, Alexander (2019). The expression of the immune checkpoint regulator VISTA correlates with improved overall survival in pT1/2 tumor stages in esophageal adenocarcinoma. OncoImmunology, 8 (5). PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 2162-402X

Loeser, Heike, Schallenberg, Simon, von Winterfeld, Moritz, Tharun, Lars, Alakus, Hakan, Hoelscher, Arnulf, Bollschweiler, Elfriede, Buettner, Reinhard, Zander, Thomas and Quaas, Alexander (2017). High protein and mRNA expression levels of TUBB3 (class III beta-tubulin) are associated with aggressive tumor features in esophageal adenocarcinomas. Oncotarget, 8 (70). S. 115179 - 115190. ORCHARD PARK: IMPACT JOURNALS LLC. ISSN 1949-2553

Loeser, Heike, Waldschmidt, Dirk, Kuetting, Fabian, Heydt, Carina, Zander, Thomas, Plum, Patrick, Alakus, Hakan, Buettner, Reinhard and Quaas, Alexander (2017). Copy-number variation and protein expression of DOT1L in pancreatic adenocarcinoma as a potential drug target. Mol. Clin. Oncol., 6 (5). S. 639 - 643. ATHENS: SPANDIDOS PUBL LTD. ISSN 2049-9469

Loeser, Heike, Waldschmidt, Dirk, Kuetting, Fabian, Schallenberg, Simon, Zander, Thomas, Bollschweiler, Elfriede, Hoelscher, Arnulf, Weckermann, Katharina, Plum, Patrick, Alakus, Hakan, Buettner, Reinhard and Quaas, Alexander (2017). Somatic BRCA1-associated protein 1 (BAP1) loss is an early and rare event in esophageal adenocarcinoma. Mol. Clin. Oncol., 7 (2). S. 225 - 229. ATHENS: SPANDIDOS PUBL LTD. ISSN 2049-9469

Macherey, Sascha, Bruns, Christiane, Alakus, Hakan, Doerr, Fabian, Heldwein, Matthias, Quaas, Alexander, Wahlers, Thorsten and Hekmat, Khosro (2018). Lung Metastasectomy in Pulmonary Metastatic Colorectal Carcinoma. Zent.bl. Chir., 143 (2). S. 193 - 204. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1438-9592

Maus, Martin K. H., Leers, Jessica, Herbold, Till, Bludau, Marc, Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Kleinert, Robert, Hescheler, Daniel A., Bollschweiler, Elfriede, Hoelscher, Arnulf H., Schaefer, Hartmut and Alakus, Hakan (2016). Gastric Outlet Obstruction After Esophagectomy: Retrospective Analysis of the Effectiveness and Safety of Postoperative Endoscopic Pyloric Dilatation. World J.Surg., 40 (10). S. 2405 - 2412. NEW YORK: SPRINGER. ISSN 1432-2323

Pamuk, Aylin, Alakus, Hakan, Eming, Sabine, Mauch, Cornelia and Bruns, Christiane . 5-year survival in metastatic melanoma under treatment with dabrafenib plus trametinib. Onkologe. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-0415

Pasternack, Helen, Fassunke, Jana, Plum, Patrick Sven, Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Hescheler, Daniel Alexander, Gassa, Asmae, Merkelbach-Bruse, Sabine, Bruns, Christiane Josephine, Perner, Sven, Hallek, Michael, Buettner, Reinhard, Bollschweiler, Elfriede, Hoelscher, Arnulf Heinrich, Quaas, Alexander, Zander, Thomas, Weiss, Jonathan and Alakus, Hakan (2018). Somatic alterations in circulating cell-free DNA of oesophageal carcinoma patients during primary staging are indicative for post-surgical tumour recurrence. Sci Rep, 8. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

Plum, Patrick Sven, Gebauer, Florian, Kraemer, Max, Alakus, Hakan, Berlth, Felix, Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Schiffmann, Lars, Zander, Thomas, Buettner, Reinhard, Hoelscher, Arnulf Heinrich, Bruns, Christiane Josephine, Quaas, Alexander and Loeser, Heike (2019). HER2/neu (ERBB2) expression and gene amplification correlates with better survival in esophageal adenocarcinoma. BMC Cancer, 19. LONDON: BMC. ISSN 1471-2407

Plum, Patrick Sven, Herbold, Till, Berlth, Felix, Christ, Hildegard ORCID: 0000-0003-3235-2994, Alakus, Hakan, Bludau, Marc, Chang, De-Hua, Bruns, Christiane Josephine, Hoelscher, Arnulf Heinrich and Chon, Seung-Hun ORCID: 0000-0002-8923-6428 (2019). Outcome of Self-Expanding Metal Stents in the Treatment of Anastomotic Leaks After Ivor Lewis Esophagectomy. World J.Surg., 43 (3). S. 862 - 870. NEW YORK: SPRINGER. ISSN 1432-2323

Plum, Patrick Sven, Hoelscher, Arnulf Heinrich, Godoy, Kristin Pacheco, Schmidt, Henner, Berlth, Felix ORCID: 0000-0002-3780-0728, Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Alakus, Hakan and Bollschweiler, Elfriede (2018). Prognosis of patients with superficial T1 esophageal cancer who underwent endoscopic resection before esophagectomy-A propensity score-matched comparison. Surg. Endosc., 32 (9). S. 3972 - 3981. NEW YORK: SPRINGER. ISSN 1432-2218

Plum, Patrick Sven, Ulase, Dita, Bollschweiler, Elfriede, Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Berlth, Felix, Zander, Thomas, Alakus, Hakan, Hoelscher, Arnulf H., Bruns, Christiane J., Schallenberg, Simon, Quaas, Alexander and Loeser, Heike (2018). Upregulation of insulin-like growth factor II mRNA-binding protein 3 (IMP3) has negative prognostic impact on early invasive (pT1) adenocarcinoma of the esophagus. J. Cancer Res. Clin. Oncol., 144 (9). S. 1731 - 1740. NEW YORK: SPRINGER. ISSN 1432-1335

Plum, Patrick Sven, Warnecke-Eberz, Ute, Drebber, Uta, Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Alakus, Hakan, Hoelscher, Arnulf Heinrich, Quaas, Alexander, Bruns, Christiane Josephine, Gockel, Ines, Lorenz, Dietmar, Metzger, Ralf and Bollschweiler, Elfriede (2019). Upregulation of miR-17-92 cluster is associated with progression and lymph node metastasis in oesophageal adenocarcinoma. Sci Rep, 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

Quaas, Alexander, Heydt, Carina, Gebauer, Florian, Alakus, Hakan, Loeser, Heike ORCID: 0000-0003-4555-1327, Buettner, Reinhard, Hillmer, Axel ORCID: 0000-0002-3381-7266, Bruns, Christiane, Merkelbach-Bruse, Sabine, Zander, Thomas and Frommolt, Peter ORCID: 0000-0002-1966-8014 (2019). Genomic Characterization of TP53-Wild-Type Esophageal Carcinoma. Transl. Oncol., 12 (1). S. 154 - 162. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1936-5233

Quaas, Alexander, Heydt, Carina, Waldschmidt, Dirk, Alakus, Hakan, Zander, Thomas, Goeser, Tobias, Kasper, Philipp, Bruns, Christiane, Brunn, Anna, Roth, Wilfried, Hartmann, Nils, Bunck, Anne, Schmidt, Matthias, Buettner, Reinhard and Merkelbach-Bruse, Sabine (2019). Alterations in ERBB2 and BRCA and microsatellite instability as new personalized treatment options in small bowel carcinoma. BMC Gastroenterol., 19. LONDON: BMC. ISSN 1471-230X

Schiffmann, Lars Mortimer, Fritsch, Melanie, Gebauer, Florian, Guenther, Saskia Diana, Stair, Neil Richard, Seeger, Jens Michael, Thangarajah, Fabinshy, Dieplinger, Georg, Bludau, Marc, Alakus, Hakan, Gobel, Heike, Quaas, Alexander, Zander, Thomas, Hilberg, Frank, Bruns, Christiane Josephine, Kashkar, Hamid and Coutelle, Oliver (2019). Tumour-infiltrating neutrophils counteract anti-VEGF therapy in metastatic colorectal cancer. Br. J. Cancer, 120 (1). S. 69 - 79. LONDON: NATURE PUBLISHING GROUP. ISSN 1532-1827

Schloesser, Hans A., Drebber, Uta, Kloth, Michael, Thelen, Martin ORCID: 0000-0002-2785-9726, Rothschild, Sacha I., Haase, Simon, Garcia-Marquez, Maria, Wennhold, Kerstin ORCID: 0000-0001-5539-7226, Berlth, Felix ORCID: 0000-0002-3780-0728, Urbanski, Alexander, Alakus, Hakan, Schauss, Astrid, Shimabukuro-Vornhagen, Alexander, Theurich, Sebastian ORCID: 0000-0001-5706-8258, Warnecke-Ebertz, Ute, Stippel, Dirk L., Zippelius, Alfred, Buettner, Reinhard, Hallek, Michael, Hoelscher, Arnulf H., Zander, Thomas, Moenig, Stefan P. and von Bergwelt-Baildon, Michael (2016). Immune checkpoints programmed death 1 ligand 1 and cytotoxic T lymphocyte associated molecule 4 in gastric adenocarcinoma. OncoImmunology, 5 (5). PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 2162-402X

Schloesser, Hans Anton, Drebber, Uta, Urbanski, Alexander, Haase, Simon, Baltin, Christoph, Berlth, Felix ORCID: 0000-0002-3780-0728, Neiss, Susanne, von Bergwelt-Baildon, Michael, Fetzner, Ulrich Klaus, Warnecke-Eberz, Ute, Bollschweiler, Elfriede, Hoelscher, Arnulf Heinrich, Moenig, Stefan Paul and Alakus, Hakan (2017). Glucose transporters 1, 3, 6, and 10 are expressed in gastric cancer and glucose transporter 3 is associated with UICC stage and survival. Gastric Cancer, 20 (1). S. 83 - 92. NEW YORK: SPRINGER. ISSN 1436-3305

Tharun, Lars, Scheel, Andreas H., Zander, Thomas, Alakus, Hakan, Buettner, Reinhard and Quaas, Alexander (2016). PD-L1 status in esophageal carcinoma at the mRNA and protein level. J. Clin. Oncol., 34 (15). ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. ISSN 1527-7755

Zander, Thomas, Alakus, Hakan and Bruns, Christiane (2016). Surgery of the primary tumor in metastatic gastric cancer. Onkologe, 22 (12). S. 996 - 999. NEW YORK: SPRINGER. ISSN 1433-0415

Zhao, Jiangang, Li, Jiahui, Schloesser, Hans A., Popp, Felix, Popp, Marie Christine, Alakus, Hakan, Jauch, Karl-Walter, Bruns, Christiane J. and Zhao, Yue (2017). Targeting Cancer Stem Cells and Their Niche: Current Therapeutic Implications and Challenges in Pancreatic Cancer. Stem Cells Int., 2017. LONDON: HINDAWI LTD. ISSN 1687-9678

Zhao, Jiangang, Schlosser, Hans A., Wang, Zhefang, Qin, Jie, Li, Jiahui, Popp, Felix, Popp, Marie Christine, Alakus, Hakan, Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Hansen, Hinrich P., Neiss, Wolfram E., Jauch, Karl-Walter, Bruns, Christiane J. and Zhao, Yue ORCID: 0000-0002-6790-3402 (2019). Tumor-Derived Extracellular Vesicles Inhibit Natural Killer Cell Function in Pancreatic Cancer. Cancers, 11 (6). BASEL: MDPI. ISSN 2072-6694

This list was generated on Sun Jan 24 04:47:11 2021 CET.