Universität zu Köln

Journal Article

Fassunke, Jana, Mueller, Fabienne, Keul, Marina, Michels, Sebastian, Dammert, Marcel A., Schmitt, Anna, Plenker, Dennis, Lategahn, Jonas ORCID: 0000-0001-5993-7082, Heydt, Carina, Braegelmann, Johannes, Tumbrink, Hannah L., Alber, Yannic, Klein, Sebastian, Heimsoeth, Alena, Dahmen, Ilona, Fischers, Rieke N., Scheffler, Matthias, Ihle, Michaela A., Priesner, Vanessa, Scheel, Andreas H., Wagener, Svenja, Kron, Anna, Frank, Konrad, Garbert, Katia, Persigehl, Thorsten, Puesken, Michael, Haneder, Stefan, Schaaf, Bernhard, Rodermann, Ernst, Engel-Riedel, Walburga, Felip, Enriqueta, Smit, Egbert F., Merkelbach-Bruse, Sabine, Reinhardt, H. Christian, Kast, Stefan M., Wolf, Juergen, Rauh, Daniel, Buettner, Reinhard and Sos, Martin L. (2018). Overcoming EGFR(G724S)-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors. Nat. Commun., 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Imielinski, Marcin, Berger, Alice H., Hammerman, Peter S., Hernandez, Bryan, Pugh, Trevor J., Hodis, Eran, Cho, Jeonghee, Suh, James, Capelletti, Marzia ORCID: 0000-0001-5095-7060, Sivachenko, Andrey, Sougnez, Carrie, Auclair, Daniel, Lawrence, Michael S., Stojanov, Petar, Cibulskis, Kristian, Choi, Kyusam, de Waal, Luc, Sharifnia, Tanaz, Brooks, Angela, Greulich, Heidi, Banerji, Shantanu, Zander, Thomas, Seidel, Danila ORCID: 0000-0003-4388-3117, Leenders, Frauke, Ansen, Sascha, Ludwig, Corinna, Engel-Riedel, Walburga, Stoelben, Erich, Wolf, Juergen, Goparju, Chandra, Thompson, Kristin, Winckler, Wendy, Kwiatkowski, David, Johnson, Bruce E., Jaenne, Pasi A., Miller, Vincent A., Pao, William, Travis, William D., Pass, Harvey I., Gabriel, Stacey B., Lander, Eric S., Thomas, Roman K., Garraway, Levi A., Getz, Gad and Meyerson, Matthew ORCID: 0000-0002-9133-8108 (2012). Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing. Cell, 150 (6). S. 1107 - 1121. CAMBRIDGE: CELL PRESS. ISSN 1097-4172

Juergens, Jessica, Engel-Riedel, Walburga, Prickartz, Alexander, Ludwig, Corinna, Schildgen, Oliver ORCID: 0000-0003-4297-9627, Tillmann, Ramona-Liza, Stoelben, Erich, Brockmann, Michael and Schildgen, Verena (2014). Combined point mutation in KRAS or EGFR genes and EML4-ALK translocation in lung cancer patients. Future Oncol., 10 (4). S. 529 - 533. LONDON: FUTURE MEDICINE LTD. ISSN 1744-8301

Michels, Sebastian, Heydt, Carina, van Veggel, Bianca, Deschler-Baier, Barbara, Pardo, Nuria, Monkhorst, Kim, Ruesseler, Vanessa, Stratmann, Jan, Griesinger, Frank, Steinhauser, Susanne, Kostenko, Anna, Diebold, Joachim, Fassunke, Jana, Fischer, Rieke, Engel-Riedel, Walburga, Gautschi, Oliver, Geissinger, Eva, Haneder, Stefan, Ihle, Michaela A., Kopp, Hans-Georg, de Langen, Adrianus J., Martinez-Marti, Alex, Nogova, Lucia, Persigehl, Thorsten, Plenker, Dennis, Puesken, Michael, Rodermann, Ernst, Rosenwald, Andreas, Scheel, Andreas H., Scheffler, Matthias, Spengler, Werner, Seggewiss-Bernhardt, Ruth, Braegelmann, Johannes, Sebastian, Martin, Vrugt, Bart, Hellmich, Martin, Sos, Martin L., Heukamp, Lukas C., Felip, Enriqueta, Merkelbach-Bruse, Sabine, Smit, Egbert F., Buettner, Reinhard and Wolf, Juergen (2019). Genomic Profiling Identifies Outcome-Relevant Mechanisms of Innate and Acquired Resistance to Third-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor Therapy in Lung Cancer. JCO Precis. Oncol., 3. ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. ISSN 2473-4284

Michels, Sebastian, Scheel, Andreas Hans, Scheffler, Matthias ORCID: 0000-0002-9031-1368, Schultheis, Anne Maria, Gautschi, Oliver, Aebersold, Franziska, Diebold, Joachim, Pall, Georg, Rothschild, Sacha ORCID: 0000-0003-1304-9340, Bubendorf, Lukas, Hartmann, Wolfgang ORCID: 0000-0002-7609-5021, Heukamp, Lukas ORCID: 0000-0002-3388-3482, Schildhaus, Hans-Ulrich, Fassunke, Jana, Ihle, Michaela Angelika, Kuenstlinger, Helen, Heydt, Carina, Fischer, Rieke, Nogova, Lucia, Mattonet, Christian, Hein, Rebecca, Adams, Anne ORCID: 0000-0003-3286-1131, Gerigk, Ulrich, Schulte, Wolfgang, Lueders, Heike, Grohe, Christian, Graeven, Ullrich, Mueller-Naendrup, Clemens, Draube, Andreas, Kambartel, Karl-Otto, Krueger, Stefan, Schulze-Olden, Susanne, Serke, Monika, Engel-Riedel, Walburga, Kaminsky, Britta, Randerath, Winfried, Merkelbach-Bruse, Sabine, Buettner, Reinhard and Wolf, Juergen (2016). Clinicopathological Characteristics of RET Rearranged Lung Cancer in European Patients. J. Thorac. Oncol., 11 (1). S. 122 - 127. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1556-1380

Michels, Sebastian Yves Friedrich, Scheffler, Matthias, Gardizi, Masyar, Christiaan, Marc, Bos, Allardt, Nogova, Lucia, Koenig, Katharine, Fassunke, Jana, Heydt, Carina, Michaela, Ihle, Kuenstlinger, Helen, Toepit, Karin, Ueckeroth, Frank, Albus, Kerstin, Serke, Monika Heidi, Randerath, Winfried, Engel-Riedel, Walburga, Merkelbach-Bruse, Sabine, Heukamp, Lukas Carl, Buettner, Reinhard and Wolf, Juergen (2014). Clinical and molecular characteristics of non-small cell lung cancer patients harboring PIK3CA mutations. J. Clin. Oncol., 32 (15). ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. ISSN 1527-7755

Peifer, Martin ORCID: 0000-0002-5243-5503, Fernandez-Cuesta, Lynnette ORCID: 0000-0002-0724-6703, Sos, Martin L., George, Julie, Seidel, Danila ORCID: 0000-0003-4388-3117, Kasper, Lawryn H., Plenker, Dennis, Leenders, Frauke, Sun, Ruping, Zander, Thomas, Menon, Roopika, Koker, Mirjam, Dahmen, Ilona, Mueller, Christian, Di Cerbo, Vincenzo ORCID: 0000-0002-2920-1274, Schildhaus, Hans-Ulrich, Altmueller, Janine, Baessmann, Ingelore, Becker, Christian, de Wilde, Bram, Vandesompele, Jo ORCID: 0000-0001-6274-0184, Boehm, Diana, Ansen, Sascha, Gabler, Franziska, Wilkening, Ines, Heynck, Stefanie, Heuckmann, Johannes M., Lu, Xin, Carter, Scott L., Cibulskis, Kristian, Banerji, Shantanu, Getz, Gad, Park, Kwon-Sik, Rauh, Daniel ORCID: 0000-0002-1970-7642, Gruetter, Christian, Fischer, Matthias, Pasqualucci, Laura, Wright, Gavin ORCID: 0000-0002-7000-9305, Wainer, Zoe, Russell, Prudence, Petersen, Iver, Chen, Yuan, Stoelben, Erich, Ludwig, Corinna, Schnabel, Philipp, Hoffmann, Hans, Muley, Thomas, Brockmann, Michael, Engel-Riedel, Walburga, Muscarella, Lucia A., Fazio, Vito M., Groen, Harry, Timens, Wim ORCID: 0000-0002-4146-6363, Sietsma, Hannie, Thunnissen, Erik ORCID: 0000-0001-5355-8508, Smit, Egbert, Heideman, Danielle A. M., Snijders, Peter J. F., Cappuzzo, Federico, Ligorio, Claudia, Damiani, Stefania, Field, John, Solberg, Steinar, Brustugun, Odd Terje, Lund-Iversen, Marius, Saenger, Joerg, Clement, Joachim H. ORCID: 0000-0002-6601-2456, Soltermann, Alex, Moch, Holger, Weder, Walter, Solomon, Benjamin, Soria, Jean-Charles, Validire, Pierre, Besse, Benjamin ORCID: 0000-0001-5090-8189, Brambilla, Elisabeth, Brambilla, Christian, Lantuejoul, Sylvie, Lorimier, Philippe, Schneider, Peter M. ORCID: 0000-0003-0744-2349, Hallek, Michael, Pao, William, Meyerson, Matthew ORCID: 0000-0002-9133-8108, Sage, Julien, Shendure, Jay ORCID: 0000-0002-1516-1865, Schneider, Robert, Buettner, Reinhard, Wolf, Juergen, Nuernberg, Peter, Perner, Sven, Heukamp, Lukas C., Brindle, Paul K., Haas, Stefan ORCID: 0000-0003-3418-3688 and Thomas, Roman K. (2012). Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer. Nature Genet., 44 (10). S. 1104 - 1113. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1546-1718

Ploenes, Till, Engel-Riedel, Walburga, Stoelben, Erich, Limmroth, Christina, Schildgen, Oliver ORCID: 0000-0003-4297-9627 and Schildgen, Verena (2016). Molecular Pathology and Personalized Medicine: The Dawn of a New Era in Companion Diagnostics-Practical Considerations about Companion Diagnostics for Non-Small-Cell-Lung-Cancer. J. Pers. Med., 6 (1). BASEL: MDPI. ISSN 2075-4426

Scheffier, Matthias, Boa, Marc Christiaan Allardt, Sos, Martin L., Heukamp, Lukas Carl, Nogova, Lucia, Koenig, Katharina, Gardizi, Masyar, Mattonet, Christian, Kahraman, Manz, Kobe, Ca, Boellaard, Ronald, Lammertsma, Adriaan A., Persigehl, Thorsten, Engel-Riedel, Walburga, Toepelt, Karin, Neumaier, Bernd, Buettner, Reinhard, Zander, Thomas and Wolf, Juergen (2014). MIMEB: A phase II trial to evaluate FDG-PET/FLT-PET, DCE-MRI and molecular biomarkers for early prediction of nonprogression in patients with advanced non-small cell lung cancer treated with erlotinib and bevacizumab. J. Clin. Oncol., 32 (15). ALEXANDRIA: AMER SOC CLINICAL ONCOLOGY. ISSN 1527-7755

Scheffler, Matthias ORCID: 0000-0002-9031-1368, Bos, Marc, Gardizi, Masyar, Koenig, Katharina, Michels, Sebastian, Fassunke, Jana, Heydt, Carina, Kuenstlinger, Helen, Ihle, Michaela, Ueckeroth, Frank, Albus, Kerstin, Serke, Monika, Gerigk, Ulrich, Schulte, Wolfgang, Toepelt, Karin, Nogova, Lucia, Zander, Thomas, Engel-Riedel, Walburga, Stoelben, Erich, Ko, Yon-Dschun, Randerath, Winfried, Kaminsky, Britta, Panse, Jens, Becker, Carolin, Hellmich, Martin, Merkelbach-Bruse, Sabine, Heukamp, Lukas C., Buettner, Reinhard and Wolf, Juergen (2015). PIK3CA mutations in non-small cell lung cancer (NSCLC): Genetic heterogeneity, prognostic impact and incidence of prior malignancies. Oncotarget, 6 (2). S. 1315 - 1327. ORCHARD PARK: IMPACT JOURNALS LLC. ISSN 1949-2553

Schildhaus, Hans-Ulrich, Heukamp, Lukas C., Merkelbach-Bruse, Sabine, Riesner, Katharina, Schmitz, Katja, Binot, Elke, Paggen, Ellen, Albus, Kerstin, Schulte, Wolfgang, Ko, Yon-Dschun, Schlesinger, Andreas, Ansen, Sascha, Engel-Riedel, Walburga, Brockmann, Michael, Serke, Monika, Gerigk, Ulrich, Huss, Sebastian, Goeke, Friederike, Perner, Sven, Hekmat, Khosro, Frank, Konrad F., Reiser, Marcel, Schnell, Roland, Bos, Marc, Mattonet, Christian, Sos, Martin, Stoelben, Erich, Wolf, Juergen, Zander, Thomas and Buettner, Reinhard (2012). Definition of a fluorescence in-situ hybridization score identifies high- and low-level FGFR1 amplification types in squamous cell lung cancer. Mod. Pathol., 25 (11). S. 1473 - 1481. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1530-0285

Schildhaus, Hans-Ulrich, Schultheis, Anne M., Rueschoff, Josef, Binot, Elke, Merkelbach-Bruse, Sabine, Fassunke, Jana, Schulte, Wolfgang, Ko, Yon-Dschun, Schlesinger, Andreas, Bos, Marc, Gardizi, Masyar, Engel-Riedel, Walburga, Brockmann, Michael, Serke, Monika, Gerigk, Ulrich, Hekmat, Khosro, Frank, Konrad F., Reiser, Marcel, Schulz, Holger, Krueger, Stefan, Stoelben, Erich, Zander, Thomas, Wolf, Juergen and Buettner, Reinhard (2015). MET Amplification Status in Therapy-Naive Adeno- and Squamous Cell Carcinomas of the Lung. Clin. Cancer Res., 21 (4). S. 907 - 916. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Schildhaus, Hans-Ulrich, Schultheis, Anne M., Rueschoff, Josef, Binot, Elke, Merkelbach-Bruse, Sabine, Fassunke, Jana, Schulte, Wolfgang, Ko, Yon-Dschun, Schlesinger, Andreas, Bos, Marc, Gardizi, Masyar, Engel-Riedel, Walburga, Brockmann, Michael, Serke, Monika, Gerigk, Ulrich, Hekmat, Khosro, Frank, Konrad F., Reiser, Marcel, Schulz, Holger, Krueger, Stefan, Stoelben, Erich, Zander, Thomas, Wolf, Juergen and Buettner, Reinhard (2015). MET Amplification Status in Therapy-Naive Adeno- and Squamous Cell Carcinomas of the Lung. Clin. Cancer Res., 21 (4). S. 907 - 916. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Seidel, Danila ORCID: 0000-0003-4388-3117, Zander, Thomas, Heukamp, Lukas C., Peifer, Martin ORCID: 0000-0002-5243-5503, Bos, Marc, Fernandez-Cuesta, Lynnette ORCID: 0000-0002-0724-6703, Leenders, Frauke, Lu, Xin, Ansen, Sascha, Gardizi, Masyar, Nguyen, Chau, Berg, Johannes, Russell, Prudence, Wainer, Zoe, Schildhaus, Hans-Ulrich, Rogers, Toni-Maree, Solomon, Benjamin, Pao, William, Carter, Scott L., Getz, Gad, Hayes, D. Neil, Wilkerson, Matthew D., Thunnissen, Erik, Travis, William D., Perner, Sven, Wright, Gavin ORCID: 0000-0002-7000-9305, Brambilla, Elisabeth, Buettner, Reinhard, Wolf, Juergen, Thomas, Roman, Gabler, Franziska, Wilkening, Ines, Mueller, Christian, Dahmen, Ilona, Menon, Roopika, Koenig, Katharina, Albus, Kerstin, Merkelbach-Bruse, Sabine, Fassunke, Jana, Schmitz, Katja, Kuenstlinger, Helen, Kleine, Michaela, Binot, Elke, Querings, Silvia, Altmueller, Janine, Boessmann, Ingelore, Nuemberg, Peter, Schneider, Peter, Bogus, Magdalena, Buettner, Reinhard, Perner, Sven, Russell, Prudence, Thunnissen, Erik, Travis, William D., Brambilla, Elisabeth, Soltermann, Alex, Moch, Holger, Brustugun, Odd Terje, Solberg, Steinar, Lund-Iversen, Marius, Helland, Aslaug ORCID: 0000-0002-5520-0275, Muley, Thomas, Hoffmann, Hans, Schnabel, Philipp A., Chen, Yuan, Groen, Harry, Timens, Wim ORCID: 0000-0002-4146-6363, Sietsma, Hannie, Clement, Joachim H. ORCID: 0000-0002-6601-2456, Weder, Walter, Saenger, Joerg, Stoelben, Erich, Ludwig, Corinna, Engel-Riedel, Walburga, Smit, Egbert, Heideman, Danille A. M., Snijders, Peter J. F., Nogova, Lucia, Sos, Martin L., Mattonet, Christian, Toepelt, Karin, Scheffler, Matthias ORCID: 0000-0002-9031-1368, Goekkurt, Eray, Kappes, Rainer, Krueger, Stefan, Kambartel, Kato, Behringer, Dirk, Schulte, Wolfgang, Galetke, Wolfgang, Randerath, Winfried, Heldwein, Matthias, Schlesinger, Andreas, Serke, Monika, Hekmat, Khosro, Frank, Konrad F., Schnell, Roland, Reiser, Marcel, Huenerlituerkoglu, Ali-Nuri, Schmitz, Stephan, Meffert, Lisa, Ko, Yon-Dschun, Litt-Lampe, Markus, Gerigk, Ulrich, Fricke, Rainer, Besse, Benjamin ORCID: 0000-0001-5090-8189, Brambilla, Christian, Lantuejoul, Sylvie, Lorimier, Philippe, Moro-Sibilot, Denis, Cappuzzo, Federico, Ligorio, Claudia, Damiani, Stefania, Field, John K. ORCID: 0000-0003-3951-6365, Hyde, Russell, Validire, Pierre, Girard, Philippe, Muscarella, Lucia A., Fazio, Vito M., Hallek, Michael, Soria, Jean-Charles, Carter, Scott L., Getz, Gad, Hayes, D. Neil, Wilkerson, Matthew D., Achter, Viktor, Lang, Ulrich ORCID: 0000-0001-7166-0805, Seidel, Danila ORCID: 0000-0003-4388-3117, Zander, Thomas, Heukamp, Lukas C., Peifer, Martin ORCID: 0000-0002-5243-5503, Bos, Marc, Pao, William, Travis, William D., Brambilla, Elisabeth, Buettner, Reinhard, Wolf, Juergen and Thomas, Roman K. (2013). A Genomics-Based Classification of Human Lung Tumors. Sci. Transl. Med., 5 (209). WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1946-6242

Weiss, Jonathan, Sos, Martin L., Seidel, Danila, Peifer, Martin ORCID: 0000-0002-5243-5503, Zander, Thomas, Heuckmann, Johannes M., Ullrich, Roland T., Menon, Roopika, Maier, Sebastian, Soltermann, Alex, Moch, Holger, Wagener, Patrick, Fischer, Florian, Heynck, Stefanie, Koker, Mirjam, Schoettle, Jakob, Leenders, Frauke, Gabler, Franziska, Dabow, Ines, Querings, Silvia, Heukamp, Lukas C., Balke-Want, Hyatt, Ansen, Sascha, Rauh, Daniel ORCID: 0000-0002-1970-7642, Baessmann, Ingelore, Altmueller, Janine, Wainer, Zoe, Conron, Matthew, Wright, Gavin ORCID: 0000-0002-7000-9305, Russell, Prudence, Solomon, Ben, Brambilla, Elisabeth, Brambilla, Christian, Lorimier, Philippe, Sollberg, Steinar, Brustugun, Odd Terje, Engel-Riedel, Walburga, Ludwig, Corinna, Petersen, Iver, Saenger, Joerg, Clement, Joachim, Groen, Harry, Timens, Wim ORCID: 0000-0002-4146-6363, Sietsma, Hannie, Thunnissen, Erik ORCID: 0000-0001-5355-8508, Smit, Egbert, Heideman, Danielle, Cappuzzo, Federico, Ligorio, Claudia, Damiani, Stefania, Hallek, Michael, Beroukhim, Rameen, Pao, William, Klebl, Bert, Baumann, Matthias, Buettner, Reinhard, Ernestus, Karen, Stoelben, Erich, Wolf, Juergen, Nuernberg, Peter, Perner, Sven and Thomas, Roman K. (2010). Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer. Sci. Transl. Med., 2 (62). WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1946-6242