Universität zu Köln

Journal Article

Beckmann, Laura, Berg, Valeska, Dickhut, Clarissa, Bloehdorn, Johannes, Bahlo, Jasmin, Robrecht, Sandra, Huelsemann, Malte, Loroch, Stefan, Merkel, Olaf, Fischer, Kirsten, Wendtner, Clemens-Martin, Stilgenbauer, Stephan, Sickmann, Albert ORCID: 0000-0002-2388-5265, Hallek, Michael, Zahedi, Rene and Frenzel, Lukas P. (2018). Integrated Proteomic and Phosphoproteomic Analysis Reveal Novel Targets and Suggest Rationale for Ibrutinib Efficacy in UM-CLL. Blood, 132. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Beckmann, Laura ORCID: 0000-0001-5207-8991, Berg, Valeska, Dickhut, Clarissa, Sun, Clare ORCID: 0000-0001-8498-4729, Merkel, Olaf, Bloehdorn, Johannes ORCID: 0000-0003-1433-9702, Robrecht, Sandra, Seifert, Marc, Guerreiro, Alexandra da Palma, Claasen, Julia, Loroch, Stefan, Oliverio, Matteo, Underbayev, Chingiz, Vaughn, Lauren, Thomalla, Daniel, Huelsemann, Malte F., Tausch, Eugen, Fischer, Kirsten, Fink, Anna Maria ORCID: 0000-0002-7669-7890, Eichhorst, Barbara, Sickmann, Albert ORCID: 0000-0002-2388-5265, Wendtner, Clemens M., Stilgenbauer, Stephan, Hallek, Michael, Wiestner, Adrian, Zahedi, Rene P. and Frenzel, Lukas P. (2021). MARCKS affects cell motility and response to BTK inhibitors in CLL. Blood, 138 (7). S. 544 - 557. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Berg, Valeska, Baatout, Dunja, Wendtner, Clemens, Hallek, Michael and Frenzel, Lukas P. (2016). APT1-Mediated Cross-Talk Between Palmitoylation and Phosphorylation Events of the BCR Pathway Sensitizes CLL Cells Towards BCR-Associated Kinase Inhibitors. Blood, 128 (22). WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Berg, Valeska, Rusch, Marion, Vartak, Nachiket, Juengst, Christian, Schauss, Astrid, Waldmann, Herbert ORCID: 0000-0002-9606-7247, Hedberg, Christian, Pallasch, Christian P., Bastiaens, Philippe, Hallek, Michael, Wendtner, Clemens-Martin and Frenzel, Lukas P. (2014). Mirs-138 and-424 Control Palmitoylation-Dependent CD95-Mediated Cell Death By Targeting Acyl Protein Thioesterases 1 and 2 in Chronic Lymphocytic Leukemia. Blood, 124 (21). WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Faitschuk, Elena, Hombach, Andreas A., Frenzel, Lukas P., Wendtner, Clemens-Martin and Abken, Hinrich (2016). Chimeric antigen receptor T cells targeting Fc mu receptor selectively eliminate CLL cells while sparing healthy B cells. Blood, 128 (13). S. 1711 - 1723. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Flores-Romero, Hector, Hohorst, Lisa, John, Malina ORCID: 0000-0003-2927-3582, Albert, Marie-Christine, King, Louise E., Beckmann, Laura, Szabo, Tamas, Hertlein, Vanessa, Luo, Xu, Villunger, Andreas ORCID: 0000-0001-8259-4153, Frenzel, Lukas P., Kashkar, Hamid and Garcia-Saez, Ana J. (2022). BCL-2-family protein tBID can act as a BAX-like effector of apoptosis. Embo J., 41 (2). HOBOKEN: WILEY. ISSN 1460-2075

Fluemann, Ruth, Rehkaemper, Tim, Nieper, Pascal, Pfeiffer, Pauline, Holzem, Alessandra, Klein, Sebastian ORCID: 0000-0002-2188-9377, Bhatia, Sanil ORCID: 0000-0001-6494-7744, Kochanek, Moritz, Kisis, Ilmars ORCID: 0000-0001-6207-3991, Pelzer, Benedikt W., Ahlert, Heinz, Hauer, Julia, Guerreiro, Alexandra da Palma, Ryan, Jeremy A., Reimann, Maurice, Riabinska, Arina, Wiederstein, Janica, Krueger, Marcus, Deckert, Martina, Altmueller, Janine, Klatt, Andreas R., Frenzel, Lukas P., Pasqualucci, Laura, Beguelin, Wendy, Melnick, Ari M., Sander, Sandrine, Montesinos-Rongen, Manuel ORCID: 0000-0003-4724-5526, Brunn, Anna, Lohneis, Philipp, Buettner, Reinhard, Kashkar, Hamid, Borkhardt, Arndt, Letai, Anthony, Persigehl, Thorsten, Peifer, Martin, Schmitt, Clemens A. ORCID: 0000-0002-4731-2226, Reinhardt, Hans Christian and Knittel, Gero ORCID: 0000-0001-8395-3701 (2021). An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities. Blood Cancer Discov., 2 (1). S. 70 - 92. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 2643-3249

Frenzel, Lukas P. (2021). PI3K/BCL2: illusion or promise for RS? Blood, 137 (24). S. 3319 - 3323. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Frenzel, Lukas P., Reinhardt, H. Christian and Pallasch, Christian P. ORCID: 0000-0001-5675-6905 (2016). Concepts of Chronic Lymphocytic Leukemia Pathogenesis: DNA Damage Response and Tumor Microenvironment. Oncol. Res. Treat., 39 (1-2). S. 9 - 16. BASEL: KARGER. ISSN 2296-5262

Goeckeritz, Elisa, Kerwien, Susan, Baumann, Michael, Wigger, Marion, Vondey, Verena, Neumann, Lars, Landwehr, Thomas, Wendtner, Clemens M., Klein, Christian ORCID: 0000-0001-7594-7280, Liu, Ningshu, Hallek, Michael, Frenzel, Lukas P. and Krause, Guenter (2015). Efficacy of phosphatidylinositol-3 kinase inhibitors with diverse isoform selectivity profiles for inhibiting the survival of chronic lymphocytic leukemia cells. Int. J. Cancer, 137 (9). S. 2234 - 2243. HOBOKEN: WILEY-BLACKWELL. ISSN 1097-0215

Guerreiro, Alexandra da Palma, Dorweiler, Cornelia, Halmer, Ismini, Merkel, Olaf, Hartmann, Elena Maria, Berg, Valeska, Reinart, Nina, Fingerle-Rowson, Guenter, Knittel, Gero, Pallasch, Christian, Rosenwald, Andreas, Reinhardt, Christian, Wendtner, Clemens-Martin, Hallek, Michael and Frenzel, Lukas P. (2018). FcmR Shapes BCR Signaling in IgM-Positive Leukemia. Blood, 132. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Guerreiro, Alexandra da Palma, Dorweiler, Cornelia, Kintzele, Laurent, Baatout, Dunja, Huelsemann, Malte, Berg, Valeska, Merkel, Olaf, Reinart, Nina, Fingerle-Rowson, Guenter, Knittel, Gero, Pallasch, Christian, Reinhardt, Hans Christian, Wendtner, Clemens Martin, Hallek, Michael and Frenzel, Lukas P. (2016). Loss of TOSO Promotes Richter's Transformation of TCL1A Driven CLL. Blood, 128 (22). WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Herling, Carmen D., Abedpour, Nima, Weiss, Jonathan, Schmitt, Anna, Jachimowicz, Ron Daniel, Merkel, Olaf ORCID: 0000-0001-5089-344X, Cartolano, Maria, Oberbeck, Sebastian, Mayer, Petra, Berg, Valeska, Thomalla, Daniel, Kutsch, Nadine, Stiefelhagen, Marius, Cramer, Paula, Wendtner, Clemens-Martin ORCID: 0000-0003-2866-2260, Persigehl, Thorsten, Saleh, Andreas, Altmueller, Janine, Nuernberg, Peter, Pallasch, Christian, Achter, Viktor, Lang, Ulrich, Eichhorst, Barbara, Castiglione, Roberta ORCID: 0000-0002-9828-4405, Schaefer, Stephan C., Buettner, Reinhard, Kreuzer, Karl-Anton, Reinhardt, Hans Christian, Hallek, Michael, Frenzel, Lukas P. and Peifer, Martin ORCID: 0000-0002-5243-5503 (2018). Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia. Nat. Commun., 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Holtick, Udo, Frenzel, Lukas P., Shimabukuro-Vornhagen, Alexander ORCID: 0000-0002-2351-7294, Theurich, Sebastian ORCID: 0000-0001-5706-8258, Claasen, Julia, Scheid, Christof, von Bergwelt-Baildon, Michael, Froehlich, Holger, Wendtner, Clemens M. and Chemnitz, Jens M. (2015). CD4+T cell counts reflect the immunosuppressive state of CD4 helper cells in patients after allogeneic stem cell transplantation. Ann. Hematol., 94 (1). S. 129 - 138. NEW YORK: SPRINGER. ISSN 1432-0584

Holtick, Udo, Herling, Marco, Frenzel, Lukas P., Herling, Carmen, Schiller, Joanna, Aguilar, Marta Rebecca Cruz, Theurich, Sebastian, Hallek, Michael and Scheid, Christof (2020). A Phase II Study to Investigate the Efficacy of shortterm Everolimus in Addition to post-transplant Cyclophosphamide as graft-versus-host-prophylaxis after Allogeneic Stem Cell Transplantation (Octet-ever). Bone Marrow Transplant., 55 (SUPPL 1). S. 290 - 292. LONDON: SPRINGERNATURE. ISSN 1476-5365

Huelsemann, Malte F., Patz, Michaela, Beckmann, Laura, Brinkmann, Kerstin, Otto, Teresa, Fandrey, Joachim, Becker, Hans Jiro, Theurich, Sebastian, von Bergwelt-Baildon, Michael S., Pallasch, Christian P., Zahedi, Rene P., Kashkar, Hamid, Reinhardt, Christian, Hallek, Michael, Wendtner, Clemens-Martin and Frenzel, Lukas P. (2014). p38 MAPK Controls Sensitivity Towards BH3 Mimetics By Regulating Mcl-1 Expression of Chronic Lymphocytic Leukemia in Hypoxia and Acquired Resistance. Blood, 124 (21). WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Knittel, Gero, Liedgens, Paul, Korovkina, Darya, Seeger, Jens M., Al-Baldawi, Yussor, Al-Maarri, Mona, Fritz, Christian, Vlantis, Katerina, Bezhanova, Svetlana ORCID: 0000-0001-7336-9210, Scheel, Andreas H., Wolz, Olaf-Oliver, Reimann, Maurice, Moeller, Peter, Lopez, Cristina ORCID: 0000-0001-6644-1659, Schlesner, Matthias ORCID: 0000-0002-5896-4086, Lohneis, Philipp, Weber, Alexander N. R., Truemper, Lorenz, Staudt, Louis M., Ortmann, Monika, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Siebert, Reiner, Schmitt, Clemens A., Klatt, Andreas R., Wunderlich, F. Thomas, Schaefer, Stephan C., Persigehl, Thorsten, Montesinos-Rongen, Manuel, Odenthal, Margarete, Buettner, Reinhard, Frenzel, Lukas P., Kashkar, Hamid and Reinhardt, H. Christian (2016). B-cell-specific conditional expression of Myd88(p.L252P) leads to the development of diffuse large B-cell lymphoma in mice. Blood, 127 (22). S. 2732 - 2742. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Knittel, Gero, Rehkaemper, Tim, Korovkina, Darya, Liedgens, Paul, Fritz, Christian, Torgovnick, Alessandro, Al-Baldawi, Yussor, Al-Maarri, Mona, Cun, Yupeng ORCID: 0000-0002-4241-8099, Fedorchenko, Oleg, Riabinska, Arina, Beleggia, Filippo ORCID: 0000-0003-0234-7094, Wunderlich, F. Thomas, Ortmann, Monika, Montesinos-Rongen, Manuel, Tausch, Eugen, Stilgenbauer, Stephan, Frenzel, Lukas P., Herling, Marco, Herling, Carmen, Bahlo, Jasmin, Hallek, Michael, Peifer, Martin ORCID: 0000-0002-5243-5503, Buettner, Reinhard, Persigehl, Thorsten and Reinhardt, H. Christian (2017). Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia. Nat. Commun., 8. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Pallasch, Christian P., Ilya, Leskov, Soto, Yadira M., Braun, Christian J., Kutsch, Nadine, Drake, Adam, Frenzel, Lukas P., Iliopoulou, Bettina, van Rooijen, Nico, Wendtner, Clemens, Hallek, Michael, Chen, Jianzhu and Hemann, Michael T. (2012). Drug-Induced Cytokine Release Sensitizes Protective Tumor Microenvironments to Antibody-Mediated Therapy. Blood, 120 (21). WASHINGTON: AMER SOC HEMATOLOGY. ISSN 0006-4971

Pallasch, Christian P. ORCID: 0000-0001-5675-6905, Leskov, Ilya, Braun, Christian J., Vorholt, Daniela, Drake, Adam, Soto-Feliciano, Yadira M., Bent, Eric H., Schwamb, Janine, Iliopoulou, Bettina, Kutsch, Nadine, van Rooijen, Nico, Frenzel, Lukas P., Wendtner, Clemens M., Heukamp, Lukas ORCID: 0000-0002-3388-3482, Kreuzer, Karl Anton, Hallek, Michael, Chen, Jianzhu and Hemann, Michael T. (2014). Sensitizing Protective Tumor Microenvironments to Antibody-Mediated Therapy. Cell, 156 (3). S. 590 - 603. CAMBRIDGE: CELL PRESS. ISSN 1097-4172

Pfannkuche, Kurt, Neuss, Sabine, Pillekamp, Frank, Frenzel, Lukas P., Attia, Wael ORCID: 0000-0001-5822-6481, Hannes, Tobias ORCID: 0000-0002-8550-2282, Salber, Jochen ORCID: 0000-0001-9738-2305, Hoss, Mareike, Zenke, Martin, Fleischmann, Bernd K., Hescheler, Juergen and Saric, Tomo ORCID: 0000-0001-8344-1095 (2010). Fibroblasts Facilitate the Engraftment of Embryonic Stem Cell-Derived Cardiomyocytes on Three-Dimensional Collagen Matrices and Aggregation in Hanging Drops. Stem Cells Dev., 19 (10). S. 1589 - 1600. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1557-8534

Riabinska, Arina, Lehrman, Daria, Jachimowicz, Ron Daniel, Knitter, Gero, Fritz, Christian, Schmitt, Anna, Geyer, Aenne, Heneweer, Carola, Wittersheim, Maike, Frenzel, Lukas P., Torgovnick, Alessandro, Wiederstein, Janica Lea, Wunderlich, Claudia Maria, Ortmann, Monika, Paillard, Arlette, Woessmann, Wilhelm, Borkhardt, Arndt, Burdach, Stefan, Hansmann, Martin-Leo, Rosenwald, Andreas, Perner, Sven, Mall, Gita, Klapper, Wolfram, Merseburg, Andrea, Krueger, Marcus ORCID: 0000-0003-2008-4582, Gruell, Holger, Persigehl, Thorsten, Wunderlich, Frank Thomas, Peifer, Martin, Utermoehlen, Olaf, Buettner, Reinhard, Beleggia, Filippo ORCID: 0000-0003-0234-7094 and Reinhardt, Hans Christian (2020). ATM activity in T cells is critical for immune surveillance of lymphoma in vivo. Leukemia, 34 (3). S. 771 - 787. LONDON: SPRINGERNATURE. ISSN 1476-5551

Schwamb, Janine, Feldhaus, Valeska, Baumann, Michael, Patz, Michaela, Brodesser, Susanne, Brinker, Reinhild, Claasen, Julia, Pallasch, Christian P. ORCID: 0000-0001-5675-6905, Hallek, Michael, Wendtner, Clemens-Martin and Frenzel, Lukas P. (2012). B-cell receptor triggers drug sensitivity of primary CLL cells by controlling glucosylation of ceramides. Blood, 120 (19). S. 3978 - 3986. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020