Universität zu Köln

Journal Article

Andree, Maria, Seeger, Jens M., Schuell, Stephan, Coutelle, Oliver, Wagner-Stippich, Diana, Wiegmann, Katja, Wunderlich, Claudia M., Brinkmann, Kerstin, Broxtermann, Pia, Witt, Axel, Fritsch, Melanie, Martinelli, Paola, Bielig, Harald, Lamkemeyer, Tobias, Rugarli, Elena I. ORCID: 0000-0002-5782-1067, Kaufmann, Thomas ORCID: 0000-0001-9906-874X, Sterner-Kock, Anja, Wunderlich, F. Thomas, Villunger, Andreas, Martins, L. Miguel, Kroenke, Martin, Kufer, Thomas A., Utermoehlen, Olaf and Kashkar, Hamid (2014). BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella. Embo J., 33 (19). S. 2171 - 2188. HOBOKEN: WILEY. ISSN 1460-2075

Fritsch, Melanie, Gunther, Saskia D., Schwarzer, Robin, Albert, Marie-Christine, Schorn, Fabian, Werthenbach, J. Paul, Schiffmann, Lars M., Stair, Neil, Stocks, Hannah ORCID: 0000-0002-4129-5138, Seeger, Jens M., Lamkanfi, Mohamed, Kroenke, Martin, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kashkar, Hamid (2019). Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis. Nature, 575 (7784). S. 683 - 700. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Graeb, Jessica, Suarez, Isabelle, van Gumpel, Edeltraud, Winter, Sandra, Schreiber, Fynn, Esser, Anna, Hoelscher, Christoph, Fritsch, Melanie, Herb, Marc ORCID: 0000-0002-7533-0288, Schramm, Michael, Wachsmuth, Laurens, Pallasch, Christian, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Kashkar, Hamid and Rybniker, Jan (2019). Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating mitochondrial membrane permeability transition. Nat. Commun., 10. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Guenther, Saskia D., Fritsch, Melanie, Seeger, Jens M., Schiffmann, Lars M., Snipas, Scott J., Coutelle, Maria, Kufer, Thomas A., Higgins, Paul G. ORCID: 0000-0001-8677-9454, Hornung, Veit, Bernardini, Maria L., Hoening, Stefan, Kroenke, Martin, Salvesen, Guy S. and Kashkar, Hamid (2020). Cytosolic Gram-negative bacteria prevent apoptosis by inhibition of effector caspases through lipopolysaccharide. NAT. MICROBIOL, 5 (2). S. 354 - 385. LONDON: NATURE PUBLISHING GROUP. ISSN 2058-5276

Schiffmann, Lars Mortimer, Fritsch, Melanie, Gebauer, Florian, Guenther, Saskia Diana, Stair, Neil Richard, Seeger, Jens Michael, Thangarajah, Fabinshy, Dieplinger, Georg, Bludau, Marc, Alakus, Hakan, Gobel, Heike, Quaas, Alexander, Zander, Thomas, Hilberg, Frank, Bruns, Christiane Josephine, Kashkar, Hamid and Coutelle, Oliver (2019). Tumour-infiltrating neutrophils counteract anti-VEGF therapy in metastatic colorectal cancer. Br. J. Cancer, 120 (1). S. 69 - 79. LONDON: NATURE PUBLISHING GROUP. ISSN 1532-1827

Simpson, Daniel S., Pang, Jiyi, Weir, Ashley ORCID: 0000-0002-3072-2616, Kong, Isabella Y., Fritsch, Melanie, Rashidi, Maryam, Cooney, James P., Davidson, Kathryn C., Speir, Mary, Djajawi, Tirta M., Hughes, Sebastian ORCID: 0000-0003-0084-5014, Mackiewicz, Liana, Dayton, Merle, Anderton, Holly, Doerflinger, Marcel, Deng, Yexuan, Huang, Allan Shuai, Conos, Stephanie A., Tye, Hazel, Chow, Seong H., Rahman, Arfatur ORCID: 0000-0001-8749-0337, Norton, Raymond S., Naderer, Thomas, Nicholson, Sandra E., Burgio, Gaetan, Man, Si Ming ORCID: 0000-0002-5079-2857, Groom, Joanna R., Herold, Marco J., Hawkins, Edwin D., Lawlor, Kate E., Strasser, Andreas, Silke, John ORCID: 0000-0002-7611-5774, Pellegrini, Marc, Kashkar, Hamid, Feltham, Rebecca ORCID: 0000-0001-8376-6869 and Vince, James E. (2022). Interferon-g primes macrophages for pathogen ligand-induced killing via a caspase-8 and mitochondrial cell death pathway. Immunity, 55 (3). S. 423 - 452. CAMBRIDGE: CELL PRESS. ISSN 1097-4180

Theobald, Sebastian J., Graeb, Jessica, Fritsch, Melanie, Suarez, Isabelle, Eisfeld, Hannah S., Winter, Sandra, Koch, Maximilian, Hoelscher, Christoph, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Kashkar, Hamid and Rybniker, Jan (2021). Gasdermin D mediates host cell death but not interleukin-1 beta secretion in Mycobacterium tuberculosis-infected macrophages. Cell Death Discov., 7 (1). LONDON: SPRINGERNATURE. ISSN 2058-7716

Thesis

Fritsch, Melanie (2020). Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis. PhD thesis, Universität zu Köln.