Universität zu Köln

2022

Jais, Alexander and Bruning, Jens C. (2022). Arcuate Nucleus-Dependent Regulation of Metabolism-Pathways to Obesity and Diabetes Mellitus. Endocr. Rev., 43 (2). S. 314 - 329. WASHINGTON: ENDOCRINE SOC. ISSN 1945-7189

Vesting, Anna Juliane, Jais, Alexander, Klemm, Paul, Steuernagel, Lukas ORCID: 0000-0003-0043-1436, Wienand, Peter, Fog-Tonnesen, Morten, Hvid, Henning, Schumacher, Anna-Lena, Kukat, Christian ORCID: 0000-0003-1508-0229, Nolte, Hendrik, Georgomanolis, Theodoros, Altmueller, Janine, Pasparakis', Manolis, Schmidt', Andreas, Krueger', Marcus, Supprian, Marc Schmidt, Waisman, Ari, Straub, Beate Katharina, Raschzok, Nathanael, Bernier, Michel, Birkenfeld, Andreas L. ORCID: 0000-0003-1407-9023, Hoevelmeyer, Nadine, Bruening, Jens C. and Wunderlich, F. Thomas (2022). NIK/MAP3K14 in hepatocytes orchestrates NASH to hepatocellular carcinoma progression via JAK2/STAT5 inhibition. Mol. Metab., 66. AMSTERDAM: ELSEVIER. ISSN 2212-8778

2021

Kumar, Marta Porniece, Cremer, Anna Lena, Klemm, Paul, Steuernagel, Lukas ORCID: 0000-0003-0043-1436, Sundaram, Sivaraj, Jais, Alexander, Hausen, A. Christine, Tao, Jenkang, Secher, Anna, Pedersen, Thomas Askov, Schwaninger, Markus, Wunderlich, F. Thomas, Lowell, Bradford B., Backes, Heiko and Bruening, Jens C. (2021). Insulin signalling in tanycytes gates hypothalamic insulin uptake and regulation of AgRP neuron activity. Nat. Metab., 3 (12). S. 1662 - 1695. BERLIN: NATURE PORTFOLIO. ISSN 2522-5812

Willenborg, Sebastian, Sanin, David E., Jais, Alexander ORCID: 0000-0002-9897-4983, Ding, Xiaolei, Ulas, Thomas, Nuechel, Julian, Popovic, Milica, MacVicar, Thomas, Langer, Thomas, Schultze, Joachim L., Gerbaulet, Alexander, Roers, Axel, Pearce, Edward J., Bruening, Jens C., Trifunovic, Aleksandra and Eming, Sabine A. (2021). Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing. Cell Metab., 33 (12). S. 2398 - 2425. CAMBRIDGE: CELL PRESS. ISSN 1932-7420

2020

Ding, Xiaolei, Willenborg, Sebastian, Bloch, Wilhelm, Wickstroem, Sara A., Wagle, Prerana, Brodesser, Susanne, Roers, Axel, Jais, Alexander ORCID: 0000-0002-9897-4983, Bruening, Jens C., Hall, Michael N., Rueegg, Markus A. and Eming, Sabine A. (2020). Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation. J. Allergy Clin. Immunol., 145 (1). S. 283 - 309. NEW YORK: MOSBY-ELSEVIER. ISSN 1097-6825

Jais, Alexander ORCID: 0000-0002-9897-4983, Paeger, Lars, Sotelo-Hitschfeld, Tamara, Bremser, Stephan, Prinzensteiner, Melanie, Klemm, Paul ORCID: 0000-0002-5985-1737, Mykytiuk, Vasyl ORCID: 0000-0001-9495-2093, Widdershooven, Pia J. M., Vesting, Anna Juliane, Grzelka, Katarzyna, Minere, Marielle, Cremer, Anna Lena, Xu, Jie, Korotkova, Tatiana, Lowell, Bradford B., Zeilhofer, Hanns Ulrich ORCID: 0000-0001-6954-4629, Backes, Heiko, Fenselau, Henning, Wunderlich, F. Thomas, Kloppenburg, Peter and Bruening, Jens C. (2020). PNOCARC Neurons Promote Hyperphagia and Obesity upon High-Fat-Diet Feeding. Neuron, 106 (6). S. 1009 - 1036. CAMBRIDGE: CELL PRESS. ISSN 1097-4199

2019

Hammerschmidt, Philipp, Ostkotte, Daniela, Nolte, Hendrik, Gerl, Mathias J., Jais, Alexander ORCID: 0000-0002-9897-4983, Brunner, Hanna L., Sprenger, Hans-Georg, Awazawa, Motoharu, Nicholls, Hayley T., Turpin-Nolan, Sarah M., Langer, Thomas, Krueger, Marcus ORCID: 0000-0003-2008-4582, Bruegger, Britta and Bruening, Jens C. (2019). CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondria! Fragmentation in Obesity. Cell, 177 (6). S. 1536 - 1576. CAMBRIDGE: CELL PRESS. ISSN 1097-4172

Turpin-Nolan, Sarah M., Hammerschmidt, Philipp, Chen, Weiyi, Jais, Alexander ORCID: 0000-0002-9897-4983, Timper, Katharina, Awazawa, Motoharu, Brodesser, Susanne and Bruening, Jens C. (2019). CerS1-Derived C-18:0 Ceramide in Skeletal Muscle Promotes Obesity-Induced Insulin Resistance. Cell Reports, 26 (1). S. 1 - 18. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

2018

Schueler, Rita, Seebeck, Nicole, Osterhoff, Martin A., Witte, Veronica, Floeel, Agnes, Busjahn, Andreas ORCID: 0000-0001-9650-6919, Jais, Alexander ORCID: 0000-0002-9897-4983, Bruening, Jens C., Frahnow, Turid ORCID: 0000-0002-3264-6039, Kabisch, Stefan ORCID: 0000-0003-1792-1757, Pivovarova, Olga, Hornemann, Silke, Kruse, Michael and Pfeiffer, Andreas F. H. (2018). VEGF and GLUT1 are highly heritable, inversely correlated and affected by dietary fat intake: Consequences for cognitive function in humans. Mol. Metab., 11. S. 129 - 137. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 2212-8778

Timper, Katharina, Paeger, Lars ORCID: 0000-0001-8716-3483, Sanchez-Lasheras, Carmen, Varela, Luis, Jais, Alexander ORCID: 0000-0002-9897-4983, Nolte, Hendrik, Vogt, Merly C., Hausen, A. Christine, Heilinger, Christian, Evers, Nadine, Pospisilik, J. Andrew, Penninger, Josef M., Taylor, Eric B., Horvath, Tamas L., Kloppenburg, Peter and Bruening, Jens Claus (2018). Mild Impairment of Mitochondrial OXPHOS Promotes Fatty Acid Utilization in POMC Neurons and Improves Glucose Homeostasis in Obesity. Cell Reports, 25 (2). S. 383 - 408. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

2017

Jais, Alexander ORCID: 0000-0002-9897-4983 and Bruening, Jens C. (2017). Hypothalamic inflammation in obesity and metabolic disease. J. Clin. Invest., 127 (1). S. 24 - 33. ANN ARBOR: AMER SOC CLINICAL INVESTIGATION INC. ISSN 1558-8238

2016

Jais, Alexander ORCID: 0000-0002-9897-4983, Solas, Maite ORCID: 0000-0001-7670-3237, Backes, Heiko, Chaurasia, Bhagirath, Kleinridders, Andre ORCID: 0000-0002-4248-6366, Theurich, Sebastian ORCID: 0000-0001-5706-8258, Mauer, Jan ORCID: 0000-0002-0189-5876, Steculorum, Sophie M., Hampel, Brigitte, Goldau, Julia, Alber, Jens, Foerster, Carola Y., Eming, Sabine A., Schwaninger, Markus ORCID: 0000-0002-4510-9718, Ferrara, Napoleone, Karsenty, Gerard ORCID: 0000-0002-9253-7627 and Bruening, Jens C. (2016). Myeloid-Cell-Derived VEGF Maintains Brain Glucose Uptake and Limits Cognitive Impairment in Obesity. Cell, 165 (4). S. 882 - 896. CAMBRIDGE: CELL PRESS. ISSN 1097-4172