Universität zu Köln

2020

Kiel, Christina ORCID: 0000-0003-3154-4847, Berber, Patricia, Karlstetter, Marcus, Aslanidis, Alexander, Strunz, Tobias ORCID: 0000-0002-3744-9595, Langmann, Thomas, Grassmann, Felix ORCID: 0000-0003-1390-7528 and Weber, Bernhard H. F. (2020). A Circulating MicroRNA Profile in a Laser-Induced Mouse Model of Choroidal Neovascularization. Int. J. Mol. Sci., 21 (8). BASEL: MDPI. ISSN 1422-0067

Strunz, Tobias ORCID: 0000-0002-3744-9595, Kiel, Christina ORCID: 0000-0003-3154-4847, Grassmann, Felix ORCID: 0000-0003-1390-7528, Ratnapriya, Rinki ORCID: 0000-0002-0469-4631, Kwicklis, Madeline, Karlstetter, Marcus, Fauser, Sascha, Arend, Nicole, Swaroop, Anand ORCID: 0000-0002-1975-1141, Langmann, Thomas, Wolf, Armin and Weber, Bernhard H. F. (2020). A mega-analysis of expression quantitative trait loci in retinal tissue. PLoS Genet., 16 (9). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1553-7404

2019

Schlereth, Simona L., Karlstetter, Marcus, Hos, Deniz, Matthaei, Mario, Cursiefen, Claus and Heindl, Ludwig M. (2019). Detection of Pro- and Antiangiogenic Factors in the Human Sclera. Curr. Eye Res., 44 (2). S. 172 - 185. PHILADELPHIA: TAYLOR & FRANCIS INC. ISSN 1460-2202

2018

Beck, Susanne C., Karlstetter, Marcus, Garrido, Marina Garcia, Feng, Yuxi, Dannhausen, Katharina, Muehlfriedel, Regine, Sothilingam, Vithiyanjali, Seebauer, Britta, Berger, Wolfgang, Hammes, Hans-Peter, Seeliger, Mathias W. and Langmann, Thomas (2018). Cystoid edema, neovascularization and inflammatory processes in the murine Norrin-deficient retina. Sci Rep, 8. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

Bock, Felix, Schneider, Ann-Charlott, Aslanidis, Alexander, Karlstetter, Marcus, Neumann, Harald, Langmann, Thomas and Cursiefen, Claus (2018). PolySia avDP20 modulates macrophage-associated corneal hem- and lymphangiogenesis. Invest. Ophthalmol. Vis. Sci., 59 (9). ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC. ISSN 1552-5783

Rashid, Khalid ORCID: 0000-0002-5070-8010, Geissl, Lea, Wolf, Anne, Karlstetter, Marcus and Larigmann, Thomas (2018). Transcriptional regulation of Translocator protein (18 kDa) (TSPO) in microglia requires Pu.1, Ap1 and Sp factors. Biochim. Biophys. Acta-Gene Regul. Mech., 1861 (12). S. 1119 - 1134. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1876-4320

Rashid, Khalid, Wolf, Anne, Karlstetter, Marcus and Langmann, Thomas (2018). Microglia-specific expression of Translocator Protein (18kDa). Invest. Ophthalmol. Vis. Sci., 59 (9). ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC. ISSN 1552-5783

Van Schil, Kristof, Naessens, Sarah, Van de Sompele, Stijn ORCID: 0000-0002-3294-0668, Carron, Marjolein, Aslanidis, Alexander, Van Cauwenbergh, Caroline ORCID: 0000-0002-1948-9091, Mayer, Anja Kathrin, Van Heetvelde, Mattias, Bauwens, Miriam, Verdin, Hannah, Coppieters, Frauke ORCID: 0000-0001-7224-0992, Greenberg, Michael E., Yang, Marty G., Karlstetter, Marcus, Langmann, Thomas, De Preter, Katleen, Kohl, Susanne, Cherry, Timothy J., Leroy, Bart P. and De Baere, Elfride ORCID: 0000-0002-5609-6895 (2018). Mapping the genomic landscape of inherited retinal disease genes prioritizes genes prone to coding and noncoding copy-number variations. Genet. Med., 20 (2). S. 202 - 214. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1530-0366

Van Schil, Kristof, Naessens, Sarah, Van de Sompele, Stijn, Carron, Marjolein, Lambrechts, Laurens, Roura, Nuria Gruartmoner, Dannhausen, Katharina, Coppieters, Frauke, Karlstetter, Marcus, Langmann, Thomas, Maroofian, Reza, Webster, Andrew, Michaelides, Michel, Leroy, Bart P. and De Baere, Elfride ORCID: 0000-0002-5609-6895 (2018). Leveraging consanguinity in inherited retinal diseases uncovers missing genetic variation: rare novel disease genes and a multitude of novel pathogenic variants in known disease genes. Invest. Ophthalmol. Vis. Sci., 59 (9). ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC. ISSN 1552-5783

2017

Karlstetter, Marcus, Dannhausen, Katharina and Langmann, Thomas (2017). Microglia and immunomodulatory therapies for retinal degenerative diseases. Med. Genet., 29 (2). S. 225 - 234. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1863-5490

Karlstetter, Marcus, Kopatz, Jens, Aslanidis, Alexander, Shahraz, Anahita, Caramoy, Albert, Linnartz-Gerlach, Bettina ORCID: 0000-0003-4485-684X, Lin, Yuchen, Lueckoff, Anika, Fauser, Sascha, Dueker, Katharina, Claude, Janine, Wang, Yiner, Ackermann, Johannes, Schmidt, Tobias ORCID: 0000-0003-3102-3515, Hornung, Veit ORCID: 0000-0002-4150-194X, Skerka, Christine, Langmann, Thomas and Neumann, Harald ORCID: 0000-0002-5071-5202 (2017). Polysialic acid blocks mononuclear phagocyte reactivity, inhibits complement activation, and protects from vascular damage in the retina. EMBO Mol. Med., 9 (2). S. 154 - 167. HOBOKEN: WILEY. ISSN 1757-4684

Kirschfink, Michael, Schick, Tina, Steinhauer, Marlin, Aslanidis, Alexander, Altay, Lebriz, Karlstetter, Marcus, Langmann, Thomas and Fauser, Sascha (2017). Local complement activation in aqueous humor in patients with age-related macular degeneration. Mol. Immunol., 89. S. 163 - 164. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. ISSN 0161-5890

Martens, Thomas F., Peynshaert, Karen ORCID: 0000-0002-2987-4938, Nascimento, Thais Leite ORCID: 0000-0002-2656-7609, Fattal, Elias ORCID: 0000-0002-3194-961X, Karlstetter, Marcus, Langmann, Thomas, Picaud, Serge ORCID: 0000-0002-0548-5145, Demeester, Jo, De Smedt, Stefaan C., Remaut, Katrien ORCID: 0000-0002-2244-1339 and Braeckmans, Kevin (2017). Effect of hyaluronic acid-binding to lipoplexes on intravitreal drug delivery for retinal gene therapy. Eur. J. Pharm. Sci., 103. S. 27 - 36. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1879-0720

Micklisch, Sven, Lin, Yuchen, Jacob, Saskia, Karlstetter, Marcus, Dannhausen, Katharina, Dasari, Prasad, von der Heide, Monika, Dahse, Hans-Martin, Schmoelz, Lisa, Grassmann, Felix ORCID: 0000-0003-1390-7528, Alene, Medhanie, Fauser, Sascha, Neumann, Harald ORCID: 0000-0002-5071-5202, Lorkowski, Stefan ORCID: 0000-0002-9649-840X, Pauly, Diana, Weber, Bernhard H., Joussen, Antonia M., Langmann, Thomas, Zipfel, Peter F. and Skerka, Christine (2017). Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator. J. Neuroinflamm., 14. LONDON: BIOMED CENTRAL LTD. ISSN 1742-2094

2016

Coppieters, Frauke ORCID: 0000-0001-7224-0992, Ascari, Giulia ORCID: 0000-0001-6175-6774, Dannhausen, Katharina, Nikopoulos, Konstantinos ORCID: 0000-0002-1856-2752, Peelman, Frank, Karlstetter, Marcus, Xu, Mingchu, Brachet, Cecile ORCID: 0000-0001-7955-2534, Meunier, Isabelle, Tsilimbaris, Miltiadis K., Tsika, Chrysanthi, Blazaki, Styliani V., Vergult, Sarah ORCID: 0000-0002-0816-6262, Farinelli, Pietro ORCID: 0000-0002-4242-3090, Van Laethem, Thalia, Bauwens, Miriam, De Bruyne, Marieke ORCID: 0000-0001-6636-5537, Chen, Rui, Langmann, Thomas, Sui, Ruifang, Meire, Francoise, Rivolta, Carlo ORCID: 0000-0002-0733-9950, Hamel, Christian P., Leroy, Bart P. and De Baere, Elfride ORCID: 0000-0002-5609-6895 (2016). Isolated and Syndromic Retinal Dystrophy Caused by Biallelic Mutations in RCBTB1, a Gene Implicated in Ubiquitination. Am. J. Hum. Genet., 99 (2). S. 470 - 481. CAMBRIDGE: CELL PRESS. ISSN 1537-6605

Schil, KristofVan, Karlstetter, Marcus, Aslanidis, Alexander, Dannhausen, Katharina, Azam, Maleeha, Qamar, Raheel, Leroy, Bart P., Depasse, Fanny, Langmann, Thomas and De Baere, Elfride ORCID: 0000-0002-5609-6895 (2016). Autosomal recessive retinitis pigmentosa with homozygous rhodopsin mutation E150K and non-coding cis-regulatory variants in CRX-binding regions of SAMD7. Sci Rep, 6. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

2015

Coppieters, Frauke, Bauwens, Miriam, Karlstetter, Marcus, Vleminckx, Kris, Van der Eecken, Morgane, Langmann, Thomas, Leroy, Bart Peter, Meire, Francoise and De Baere, Elfride ORCID: 0000-0002-5609-6895 (2015). Mutation of RCBTB1 in a severe syndromic retinal ciliopathy. Invest. Ophthalmol. Vis. Sci., 56 (7). ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC. ISSN 1552-5783

Dannhausen, Katharina, Karlstetter, Marcus, Caramoy, Albert, Volz, Cornelia, Jaegle, Herbert, Liebisch, Gerhard ORCID: 0000-0003-4886-0811, Utermoehlen, Olaf and Langmann, Thomas (2015). Acid sphingomyelinase (aSMase) deficiency leads to abnormal microglia behavior and disturbed retinal function. Biochem. Biophys. Res. Commun., 464 (2). S. 434 - 441. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE. ISSN 1090-2104

Karlstetter, Marcus, Claude, Janine, Caramoy, Albert, Linnartz-Gerlach, Bettina, Kopatz, Jens, Lueckoff, Anika, Wang, Yiner, Skerka, Christine, Neumann, Harald and Langmann, Thomas (2015). Polysialic acid attenuates alternative complement activation, inhibits microglial reactivity and reduces vascular leakage after retinal laser-damage. Invest. Ophthalmol. Vis. Sci., 56 (7). ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC. ISSN 1552-5783

Karlstetter, Marcus, Scholz, Rebecca, Rutar, Matt, Wong, Wai T., Provis, Jan M. and Langmann, Thomas (2015). Retinal microglia: Just bystander or target for therapy? Prog. Retin. Eye Res., 45. S. 30 - 58. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. ISSN 1873-1635

Karlstetter, Marcus, Scholz, Rebecca, Rutar, Matt, Wong, Wai T., Provis, Jan M. and Langmann, Thomas (2015). Retinal microglia: Just bystander or target for therapy? Prog. Retin. Eye Res., 45. S. 30 - 58. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. ISSN 1873-1635

Scholz, Rebecca, Aslanidis, Alexander, Karlstetter, Marcus, Rashid, Khalid, Grimm, Christian and Langmann, Thomas (2015). Targeting the translocator protein (18kDa) (TSPO) prevents microglia reactivity and protects from from light induced retinal degeneration. Invest. Ophthalmol. Vis. Sci., 56 (7). ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC. ISSN 1552-5783

Van Cauwenbergh, Caroline, Vleminckx, Kris, Coppieters, Frauke, Karlstetter, Marcus, Langmann, Thomas, Manes, Gael, Hamel, Christian P., Leroy, Bart Peter and De Baere, Elfride ORCID: 0000-0002-5609-6895 (2015). SF3B2, a novel candidate gene for autosomal dominant retinitis pigmentosa, encodes a component of the U2 small nuclear ribonucleoprotein. Invest. Ophthalmol. Vis. Sci., 56 (7). ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC. ISSN 1552-5783

Van Schil, Kristof, Karlstetter, Marcus, Aslanidis, Alexander, Leroy, Bart Peter, Coppieters, Frauke, Depasse, Fanny, Langmann, Thomas and De Baere, Elfride ORCID: 0000-0002-5609-6895 (2015). Recessive RHO mutation E150K and SAMD7 regulatory variants in a consanguineous family with retinitis pigmentosa. Invest. Ophthalmol. Vis. Sci., 56 (7). ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC. ISSN 1552-5783

Van Schil, Kristof, Meire, Francoise, Karlstetter, Marcus, Bauwens, Miriam, Verdin, Hannah, Coppieters, Frauke ORCID: 0000-0001-7224-0992, Scheiffert, Eva, Van Nechel, Christian, Langmann, Thomas, Deconinck, Nicolas and De Baere, Elfride ORCID: 0000-0002-5609-6895 (2015). Early-onset autosomal recessive cerebellar ataxia associated with retinal dystrophy: new human hotfoot phenotype caused by homozygous GRID2 deletion. Genet. Med., 17 (4). S. 291 - 300. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1530-0366

Van Schil, Kristof, Meire, Francoise, Karlstetter, Marcus, Bauwens, Miriam, Verdin, Hannah, Coppieters, Frauke ORCID: 0000-0001-7224-0992, Scheiffert, Eva, Van Nechel, Christian, Langmann, Thomas, Deconinck, Nicolas and De Baere, Elfride ORCID: 0000-0002-5609-6895 (2015). Early-onset autosomal recessive cerebellar ataxia associated with retinal dystrophy: new human hotfoot phenotype caused by homozygous GRID2 deletion. Genet. Med., 17 (4). S. 291 - 300. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1530-0366

2014

Aslanidis, Alexander, Karlstetter, Marcus, Walczak, Yana, Jaegle, Herbert and Langmann, Thomas (2014). RETINA-Specific Expression of Kcnv2 Is Controlled by Cone-Rod Homeobox (Crx) and Neural Retina Leucine Zipper (Nrl). S. 31 - 42. BERLIN: SPRINGER-VERLAG BERLIN. ISSN 0065-2598

Ersoy, Lebriz, Ristau, Tina, Hahn, Moritz, Karlstetter, Marcus, Langmann, Thomas, Droege, Katharina, Caramoy, Albert, den Hollander, Anneke I. and Fauser, Sascha (2014). Genetic and Environmental Risk Factors for Age-Related Macular Degeneration in Persons 90 Years and Older. Invest. Ophthalmol. Vis. Sci., 55 (3). S. 1842 - 1848. ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC. ISSN 1552-5783

Karlstetter, Marcus and Langmann, Thomas (2014). Microglia in the Aging Retina. S. 207 - 213. BERLIN: SPRINGER-VERLAG BERLIN. ISSN 2214-8019

Karlstetter, Marcus, Nothdurfter, Caroline, Aslanidis, Alexander, Moeller, Katharina, Horn, Felicitas, Scholz, Rebecca, Neumann, Harald ORCID: 0000-0002-5071-5202, Weber, Bernhard H. F., Rupprecht, Rainer and Langmann, Thomas (2014). Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis. J. Neuroinflamm., 11. LONDON: BIOMED CENTRAL LTD. ISSN 1742-2094

Karlstetter, Marcus, Sorusch, Nasrin, Caramoy, Albert, Dannhausen, Katharina, Aslanidis, Alexander, Fauser, Sascha, Boesl, Michael R., Nagel-Wolfrum, Kerstin, Tamm, Ernst R., Jaegle, Herbert, Stoehr, Heidi, Wolfrum, Uwe and Langmann, Thomas (2014). Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration. Hum. Mol. Genet., 23 (19). S. 5197 - 5211. OXFORD: OXFORD UNIV PRESS. ISSN 1460-2083

Micklisch, Sven, Karlstetter, Marcus, Schmoelz, Lisa, Dahse, Hans-Martin, Weber, Bernhard H., Lorkowski, Stefan ORCID: 0000-0002-9649-840X, Langmann, Thomas, Zipfel, Peter F. and Skerka, Christine (2014). Age related maculopathy susceptibility protein 2 (ARMS2) mediates opsonization of apoptotic cells. Mol. Immunol., 61 (2). S. 222 - 223. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. ISSN 0161-5890

Van Schil, Kristof, Karlstetter, Marcus, Meire, Francoise, Bauwens, Miriam, Verdin, Hannah, Coppieters, Frauke, Scheiffert, Eva, Deconinck, Nicolas, Langmann, Thomas and De Baere, Elfride ORCID: 0000-0002-5609-6895 (2014). Homozygous deletion of glutamate receptor gene GRID2 causes new hotfoot mutant phenotype, characterized by early-onset cerebellar ataxia and retinal dystrophy. Invest. Ophthalmol. Vis. Sci., 55 (13). ROCKVILLE: ASSOC RESEARCH VISION OPHTHALMOLOGY INC. ISSN 1552-5783

2013

Mirza, Myriam, Volz, Cornelia, Karlstetter, Marcus, Langiu, Monica ORCID: 0000-0003-0719-8999, Somogyi, Aleksandra, Ruonala, Mika O., Tamm, Ernst R., Jaegle, Herbert and Langmann, Thomas (2013). Progressive Retinal Degeneration and Glial Activation in the CLN6(nclf) Mouse Model of Neuronal Ceroid Lipofuscinosis: A Beneficial Effect of DHA and Curcumin Supplementation. PLoS One, 8 (10). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203