Universität zu Köln

Journal Article

Asif, Maria, Kaygusuz, Emrah, Shinawi, Marwan, Nickelsen, Anna, Hsieh, Tzung-Chien, Wagle, Prerana, Budde, Birgit S., Hochscherf, Jennifer ORCID: 0000-0002-4412-7391, Abdullah, Uzma, Honing, Stefan, Nienberg, Christian, Lindenblatt, Dirk, Noegel, Angelika A., Altmuller, Janine ORCID: 0000-0003-4372-1521, Thiele, Holger, Motameny, Susanne, Fleischer, Nicole, Segal, Idan, Pais, Lynn, Tinschert, Sigrid, Samra, Nadra Nasser, Savatt, Juliann M., Rudy, Natasha L., De Luca, Chiara, Fortugno, Paola, White, Susan M., Krawitz, Peter, Hurst, Anna C. E., Niefind, Karsten ORCID: 0000-0002-0183-6315, Jose, Joachim ORCID: 0000-0002-0666-2676, Brancati, Francesco, Nurnberg, Peter and Hussain, Muhammad Sajid ORCID: 0000-0002-1353-8809 (2022). De novo variants of CSNK2B cause a new intellectual disability-craniodigital syndrome by disrupting the canonical Wnt signaling pathway. Hum. Genet. Genom. Adv., 3 (3). AMSTERDAM: ELSEVIER. ISSN 2666-2477

Hochscherf, Jennifer ORCID: 0000-0002-4412-7391, Lindenblatt, Dirk, Steinkrtiger, Michaela, Yoo, Eungyoung, Ulucan, Oezlem, Herzig, Stefan, Issinger, Olaf-Georg, Helms, Volkhard ORCID: 0000-0002-2180-9154, Goetz, Claudia, Neundorf, Ines ORCID: 0000-0001-6450-3991, Niefind, Karsten ORCID: 0000-0002-0183-6315 and Pietsch, Markus (2015). Development of a high-throughput screening-compatible assay to identify inhibitors of the CK2 alpha/CK2 beta interaction. Anal. Biochem., 468. S. 4 - 15. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE. ISSN 1096-0309

Hochscherf, Jennifer ORCID: 0000-0002-4412-7391, Lindenblatt, Dirk, Witulski, Benedict, Birus, Robin, Aichele, Dagmar, Marminon, Christelle ORCID: 0000-0002-4043-3949, Bouaziz, Zouhair, Le Borgne, Marc ORCID: 0000-0003-1398-075X, Jose, Joachim and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2017). Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2 alpha and Its Paralog CK2 alpha '. Pharmaceuticals, 10 (4). BASEL: MDPI. ISSN 1424-8247

Lindenblatt, Dirk ORCID: 0000-0002-5561-1082, Applegate, Violetta ORCID: 0000-0003-4120-7983, Nickelsen, Anna, Klussmann, Merlin, Neundorf, Ines, Goetz, Claudia, Jose, Joachim ORCID: 0000-0002-0666-2676 and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2022). Molecular Plasticity of Crystalline CK2 alpha ' Leads to KN2, a Bivalent Inhibitor of Protein Kinase CK2 with Extraordinary Selectivity. J. Med. Chem., 65 (2). S. 1302 - 1313. WASHINGTON: AMER CHEMICAL SOC. ISSN 1520-4804

Lindenblatt, Dirk ORCID: 0000-0002-5561-1082, Horn, Mareike, Goetz, Claudia, Niefind, Karsten ORCID: 0000-0002-0183-6315, Neundorf, Ines ORCID: 0000-0001-6450-3991 and Pietsch, Markus (2019). Design of CK2 beta-Mimicking Peptides as Tools To Study the CK2 alpha/CK2 beta Interaction in Cancer Cells. ChemMedChem, 14 (8). S. 833 - 842. WEINHEIM: WILEY-V C H VERLAG GMBH. ISSN 1860-7187

Lindenblatt, Dirk ORCID: 0000-0002-5561-1082, Nickelsen, Anna, Applegate, Violetta M., Hochscherf, Jennifer, Witulski, Benedict, Bouaziz, Zouhair, Marminon, Christelle ORCID: 0000-0002-4043-3949, Bretner, Maria, Le Borgne, Marc ORCID: 0000-0003-1398-075X, Jose, Joachim and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2019). Diacritic Binding of an Indenoindole Inhibitor by CK2 alpha Paralogs Explored by a Reliable Path to Atomic Resolution CK2 alpha ' Structures. ACS Omega, 4 (3). S. 5471 - 5479. WASHINGTON: AMER CHEMICAL SOC. ISSN 2470-1343

Lindenblatt, Dirk ORCID: 0000-0002-5561-1082, Nickelsen, Anna, Applegate, Violetta M., Jose, Joachim and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2020). Structural and Mechanistic Basis of the Inhibitory Potency of Selected 2-Aminothiazole Compounds on Protein Kinase CK2. J. Med. Chem., 63 (14). S. 7766 - 7773. WASHINGTON: AMER CHEMICAL SOC. ISSN 1520-4804

Werner, Christian, Gast, Alexander, Lindenblatt, Dirk, Nickelsen, Anna, Niefind, Karsten ORCID: 0000-0002-0183-6315, Jose, Joachim ORCID: 0000-0002-0666-2676 and Hochscherf, Jennifer ORCID: 0000-0002-4412-7391 (2022). Structural and Enzymological Evidence for an Altered Substrate Specificity in Okur-Chung Neurodevelopmental Syndrome Mutant CK2 alpha(Lys198Arg). Front. Mol. Biosci., 9. LAUSANNE: FRONTIERS MEDIA SA. ISSN 2296-889X

Thesis

Lindenblatt, Dirk ORCID: 0000-0002-5561-1082 (2022). Structural Exploration of Different Binding Pockets Suitable to Affect Protein Kinases CK2α and CK2α’ With Peptides and Small Molecules. PhD thesis, Universität zu Köln.