Universität zu Köln

Journal Article

Acharya, Aviseka, Brungs, Sonja, Henry, Margit, Rotshteyn, Tamara, Yaduvanshi, Nirmala Singh, Wegener, Lucia, Jentzsch, Simon, Hescheler, Juergen, Hemmersbach, Ruth, Boeuf, Helene and Sachinidis, Agapios (2018). Modulation of Differentiation Processes in Murine Embryonic Stem Cells Exposed to Parabolic Flight-Induced Acute Hypergravity and Microgravity. Stem Cells Dev., 27 (12). S. 838 - 848. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1557-8534

Acharya, Aviseka, Brungs, Sonja, Lichterfeld, Yannick, Hescheler, Juergen, Hemmersbach, Ruth, Boeuf, Helene ORCID: 0000-0002-3006-8773 and Sachinidis, Agapios (2019). Parabolic, Flight-Induced, Acute Hypergravity and Microgravity Effects on the Beating Rate of Human Cardiomyocytes. Cells, 8 (4). BASEL: MDPI. ISSN 2073-4409

Acharya, Aviseka, Nemade, Harshal ORCID: 0000-0002-2704-181X, Papadopoulos, Symeon, Hescheler, Jurgen, Neumaier, Felix, Schneider, Toni, Prasad, Krishna Rajendra, Khan, Khadija, Hemmersbach, Ruth, Gusmao, Eduardo Gade, Mizi, Athanasia, Papantonis, Argyris and Sachinidis, Agapios (2022). Microgravity-induced stress mechanisms in human stem cell-derived cardiomyocytes. iScience, 25 (7). CAMBRIDGE: CELL PRESS. ISSN 2589-0042

Acharya, Aviseka, Nemade, Harshal ORCID: 0000-0002-2704-181X, Prasad, Krishna Rajendra, Khan, Khadija, Hescheler, Juergen, Blackburn, Nick, Hemmersbach, Ruth, Papadopoulos, Symeon and Sachinidis, Agapios (2022). Live-Cell Imaging of the Contractile Velocity and Transient Intracellular Ca2+ Fluctuations in Human Stem Cell-Derived Cardiomyocytes. Cells, 11 (8). BASEL: MDPI. ISSN 2073-4409

Ahuja, Gaurav ORCID: 0000-0002-2837-9361, Bartsch, Deniz, Yao, Wenjie, Geissen, Simon, Frank, Stefan, Aguirre, Aitor ORCID: 0000-0002-1383-2792, Russ, Nicole, Messling, Jan-Erik ORCID: 0000-0003-3843-0041, Dodzian, Joanna, Lagerborg, Kim A., Vargas, Natalia Emilse, Muck, Joscha Sergej, Brodesser, Susanne, Baldus, Stephan, Sachinidis, Agapios, Hescheler, Juergen, Dieterich, Christoph, Trifunovic, Aleksandra, Papantonis, Argyris ORCID: 0000-0001-7551-1073, Petrascheck, Michael, Klinke, Anna, Jain, Mohit, Valenzano, Dario Riccardo and Kurian, Leo ORCID: 0000-0001-7466-5169 (2019). Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart. EMBO Rep., 20 (4). HOBOKEN: WILEY. ISSN 1469-3178

Aksoy, Irene ORCID: 0000-0003-4353-5876, Giudice, Vincent, Delahaye, Edwige, Wianny, Florence, Aubry, Maxime, Mure, Magali, Chen, Jiaxuan, Jauch, Ralf ORCID: 0000-0002-6590-9579, Bogu, Gireesh K., Nolden, Tobias, Himmelbauer, Heinz ORCID: 0000-0001-8897-2928, Xavier Doss, Michael, Sachinidis, Agapios, Schulz, Herbert, Hummel, Oliver, Martinelli, Paola ORCID: 0000-0002-1643-8731, Huebner, Norbert, Stanton, Lawrence W., Real, Francisco X., Bourillot, Pierre-Yves ORCID: 0000-0003-1657-8555 and Savatier, Pierre (2014). Klf4 and Klf5 differentially inhibit mesoderm and endoderm differentiation in embryonic stem cells. Nat. Commun., 5. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Albrecht, Wiebke, Kappenberg, Franziska ORCID: 0000-0001-8066-5333, Brecklinghaus, Tim ORCID: 0000-0001-6650-9166, Stoeber, Regina, Marchan, Rosemarie, Zhang, Mian, Ebbert, Kristina, Kirschner, Hendrik, Grinberg, Marianna, Leist, Marcel ORCID: 0000-0002-3778-8693, Moritz, Wolfgang, Cadenas, Cristina, Ghallab, Ahmed ORCID: 0000-0003-0695-3403, Reinders, Joerg, Vartak, Nachiket, van Thriel, Christoph ORCID: 0000-0003-3215-9262, Golka, Klaus, Tolosa, Laia ORCID: 0000-0002-1740-0874, Castell, Jose V. ORCID: 0000-0003-1179-6430, Damm, Georg, Seehofer, Daniel, Lampen, Alfonso, Braeuning, Albert, Buhrke, Thorsten, Behr, Anne-Cathrin, Oberemm, Axel, Gu, Xiaolong, Kittana, Naim ORCID: 0000-0003-2758-271X, van de Water, Bob, Kreiling, Reinhard, Fayyaz, Susann, van Aerts, Leon, Smedsrod, Bard, Ellinger-Ziegelbauer, Heidrun, Steger-Hartmann, Thomas, Gundert-Remy, Ursula, Zeigerer, Anja ORCID: 0000-0003-4072-0566, Ullrich, Anett, Runge, Dieter, Lee, Serene M. L., Schiergens, Tobias S., Kuepfer, Lars ORCID: 0000-0002-8741-7786, Aguayo-Orozco, Alejandro, Sachinidis, Agapios, Edlund, Karolina, Gardner, Iain, Rahnenfuehrer, Joerg and Hengstler, Jan G. (2019). Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations. Arch. Toxicol., 93 (6). S. 1609 - 1638. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Argenziano, Mariana A., Doss, Michael Xavier, Tabler, Megan, Sachinidis, Agapios and Antzelevitch, Charles ORCID: 0000-0001-7349-1582 (2019). Transcriptional changes associated with advancing stages of heart failure underlie atrial and ventricular arrhythmogenesis. PLoS One, 14 (5). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

Arshaad, Muhammad Imran, Siwek, Magdalena Elisabeth, Henseler, Christina, Daubner, Johanna, Ehninger, Dan, Hescheler, Juergen, Sachinidis, Agapios, Broich, Karl, Papazoglou, Anna and Weiergraeber, Marco (2021). Enhanced hippocampal type II theta activity AND altered theta architecture in mice lacking the Ca(v)3.2 T-type voltage-gated calcium channel. Sci Rep, 11 (1). BERLIN: NATURE PORTFOLIO. ISSN 2045-2322

Attia, Wael A., Abd El Aziz, Osama M., Spitkovsky, Dimitry, Gaspar, John A., Droege, Peter, Suhr, Frank, Sabour, Davood, Winkler, Johannes, Meganathan, Kesavan, Jagtap, Smita, Khalil, Markus, Hescheler, Juergen, Brockmeier, Konrad, Sachinidis, Agapios and Pfannkuche, Kurt (2014). Evidence for self-maintaining pluripotent murine stem cells in embryoid bodies. Stem Cell Rev. Rep., 10 (1). S. 1 - 16. TOTOWA: HUMANA PRESS INC. ISSN 1558-6804

Balmer, Nina V., Klima, Stefanie, Rempel, Eugen, Ivanova, Violeta N., Kolde, Raivo ORCID: 0000-0003-2886-6298, Weng, Matthias K., Meganathan, Kesavan, Henry, Margit, Sachinidis, Agapios, Berthold, Michael R., Hengstler, Jan G., Rahnenfuhrer, Jorg ORCID: 0000-0002-8947-440X, Waldmann, Tanja and Leist, Marcel ORCID: 0000-0002-3778-8693 (2014). From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects. Arch. Toxicol., 88 (7). S. 1451 - 1469. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Balmer, Nina V., Weng, Matthias K., Zimmer, Bastian ORCID: 0000-0003-0004-4890, Ivanova, Violeta N., Chambers, Stuart M., Nikolaeva, Elena, Jagtap, Smita, Sachinidis, Agapios, Hescheler, Juergen, Waldmann, Tanja ORCID: 0000-0001-9276-1592 and Leist, Marcel ORCID: 0000-0002-3778-8693 (2012). Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome. Hum. Mol. Genet., 21 (18). S. 4104 - 4115. OXFORD: OXFORD UNIV PRESS. ISSN 1460-2083

Burashnikov, Alexander, Di Diego, Jose M., Sicouri, Serge, Doss, Michael Xavier, Sachinidis, Agapios, Barajas-Martinez, Hector, Hu, Dan ORCID: 0000-0002-0994-8434, Minoura, Yoshino, Moise, N. Sydney, Kornreich, Bruce G., Chi, Liguo, Belardinelli, Luiz and Antzelevitch, Charles ORCID: 0000-0001-7349-1582 (2014). A temporal window of vulnerability for development of atrial fibrillation with advancing heart failure. Eur. J. Heart Fail., 16 (3). S. 271 - 281. HOBOKEN: WILEY-BLACKWELL. ISSN 1879-0844

Campos, Gisela, Schmidt-Heck, Wolfgang, De Smedt, Jonathan, Widera, Agata, Ghallab, Ahmed ORCID: 0000-0003-0695-3403, Puetter, Larissa, Gonzalez, Daniela, Edlund, Karolina, Cadenas, Cristina, Marchan, Rosemarie, Guthke, Reinhard, Verfaillie, Catherine, Hetz, Claudio, Sachinidis, Agapios, Braeuning, Albert, Schwarz, Michael, Weiss, Thomas S. ORCID: 0000-0003-0336-0581, Banhart, Benjamin K., Hoek, Jan, Vadigepalli, Rajanikanth, Willy, Jeffrey, Stevens, James L., Hay, David C., Hengstler, Jan G. and Godoy, Patricio (2020). Inflammation-associated suppression of metabolic gene networks in acute and chronic liver disease. Arch. Toxicol., 94 (1). S. 205 - 218. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Campos, Gisela, Schmidt-Heck, Wolfgang, Ghallab, Ahmed ORCID: 0000-0003-0695-3403, Rochlitz, Katharina, Puetter, Larissa, Medinas, Danilo B., Hetz, Claudio, Widera, Agata, Cadenas, Cristina, Begher-Tibbe, Brigitte, Reif, Raymond, Guenther, Georgia, Sachinidis, Agapios, Hengstler, Jan G. and Godoy, Patricio ORCID: 0000-0001-7882-5369 (2014). The transcription factor CHOP, a central component of the transcriptional regulatory network induced upon CCl4 intoxication in mouse liver, is not a critical mediator of hepatotoxicity. Arch. Toxicol., 88 (6). S. 1267 - 1281. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Chaudhari, Umesh ORCID: 0000-0002-7743-4371, Ellis, James K., Wagh, Vilas, Nemade, Harshal, Hescheler, Jurgen, Keun, Hector C. and Sachinidis, Agapios (2017). Metabolite signatures of doxorubicin induced toxicity in human induced pluripotent stem cell-derived cardiomyocytes. Amino Acids, 49 (12). S. 1955 - 1964. WIEN: SPRINGER WIEN. ISSN 1438-2199

Chaudhari, Umesh ORCID: 0000-0002-7743-4371, Nemade, Harshal, Gaspar, John Antonydas, Hescheler, Jurgen, Hengstler, Jan G. and Sachinidis, Agapios (2016). MicroRNAs as early toxicity signatures of doxorubicin in human-induced pluripotent stem cell-derived cardiomyocytes. Arch. Toxicol., 90 (12). S. 3087 - 3099. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Chaudhari, Umesh ORCID: 0000-0002-7743-4371, Nemade, Harshal, Sureshkumar, Poornima, Vinken, Mathieu ORCID: 0000-0001-5115-8893, Ates, Gamze ORCID: 0000-0002-9323-3465, Rogiers, Vera ORCID: 0000-0003-0635-7740, Hescheler, Juergen, Hengstler, Jan Georg and Sachinidis, Agapios (2018). Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes. Arch. Toxicol., 92 (1). S. 371 - 382. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Chaudhari, Umesh ORCID: 0000-0002-7743-4371, Nemade, Harshal, Wagh, Vilas, Gaspar, John Antonydas, Ellis, James K., Srinivasan, Sureshkumar Perumal, Spitkovski, Dimitry, Nguemo, Filomain, Louisse, Jochem, Bremer, Susanne, Hescheler, Juergen, Keun, Hector C., Hengstler, Jan G. and Sachinidis, Agapios (2016). Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment. Arch. Toxicol., 90 (11). S. 2763 - 2778. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Cherianidou, Anna, Seidel, Florian ORCID: 0000-0002-4466-332X, Kappenberg, Franziska ORCID: 0000-0001-8066-5333, Dreser, Nadine, Blum, Jonathan ORCID: 0000-0002-2058-0511, Waldmann, Tanja ORCID: 0000-0001-9276-1592, Bluethgen, Nils, Meisig, Johannes, Madjar, Katrin ORCID: 0000-0001-6169-8105, Henry, Margit, Rotshteyn, Tamara, Marchan, Rosemarie, Edlund, Karolina, Leist, Marcel ORCID: 0000-0002-3778-8693, Rahnenfuhrer, Joerg, Sachinidis, Agapios and Hengstler, Jan G. (2022). Classification of Developmental Toxicants in a Human iPSC Transcriptomics-Based Test. Chem. Res. Toxicol., 35 (5). S. 760 - 774. WASHINGTON: AMER CHEMICAL SOC. ISSN 1520-5010

Colaianna, Marilena, Ilmjarv, Sten, Peterson, Hedi ORCID: 0000-0001-9951-5116, Kern, Ilse, Julien, Stephanie, Baquie, Mathurin, Pallocca, Giorgia, Bosgra, Sieto, Sachinidis, Agapios, Hengstler, Jan G., Leist, Marcel ORCID: 0000-0002-3778-8693 and Krause, Karl-Heinz ORCID: 0000-0002-9033-6768 (2017). Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay. Arch. Toxicol., 91 (1). S. 365 - 392. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Colleoni, Silvia, Galli, Cesare, Gaspar, John Antony, Meganathan, Kesavan, Jagtap, Smita, Hescheler, Jurgen, Sachinidis, Agapios and Lazzari, Giovanna (2011). Development of a Neural Teratogenicity Test Based on Human Embryonic Stem Cells: Response to Retinoic Acid Exposure. Toxicol. Sci., 124 (2). S. 370 - 378. OXFORD: OXFORD UNIV PRESS. ISSN 1096-0929

Colleoni, Silvia, Galli, Cesare, Gaspar, John Antony, Meganathan, Kesavan, Jagtap, Smita, Hescheler, Jurgen, Zagoura, Dimitra, Bremer, Susanne, Sachinidis, Agapios and Lazzari, Giovanna (2014). A comparative transcriptomic study on the effects of valproic acid on two different hESCs lines in a neural teratogenicity test system. Toxicol. Lett., 231 (1). S. 38 - 45. CLARE: ELSEVIER IRELAND LTD. ISSN 1879-3169

Czepukojc, Beate, Abuhaliema, Ali, Barghash, Ahmad, Tierling, Sascha, Nass, Norbert ORCID: 0000-0003-2563-0386, Simon, Yvette, Koerbel, Christina, Cadenas, Cristina, van Hul, Noemi, Sachinidis, Agapios, Hengstler, Jan G., Helms, Volkhard, Laschke, Matthias W., Walter, Joern, Haybaeck, Johannes, Leclercq, Isabelle, Kiemer, Alexandra K. ORCID: 0000-0002-7224-9900 and Kessler, Sonja M. (2019). IGF2 mRNA Binding Protein 2 Transgenic Mice Are More Prone to Develop a Ductular Reaction and to Progress Toward Cirrhosis. Front. Med., 6. LAUSANNE: FRONTIERS MEDIA SA. ISSN 2296-858X

De Kock, Joery ORCID: 0000-0002-4078-4896, Meuleman, Philip ORCID: 0000-0001-6821-234X, Raicevic, Gordana, Rodrigues, Robim M., Branson, Steven, Meganathan, Kesavan, De Boe, Veerle, Sachinidis, Agapios, Leroux-Roels, Geert, Vanhaecke, Tamara ORCID: 0000-0002-6685-7299, Lagneaux, Laurence, Rogiers, Vera ORCID: 0000-0003-0635-7740 and Najar, Mehdi (2014). Human Skin-Derived Precursor Cells Are Poorly Immunogenic and Modulate the Allogeneic Immune Response. Stem Cells, 32 (8). S. 2215 - 2229. HOBOKEN: WILEY. ISSN 1549-4918

De Kock, Joery ORCID: 0000-0002-4078-4896, Najar, Mehdi, Bolleyn, Jennifer, Al Battah, Feras, Rodrigues, Robim M., Buyl, Karolien ORCID: 0000-0002-4889-9284, Raicevic, Gordana, Govaere, Olivier ORCID: 0000-0002-4426-6930, Branson, Steven, Meganathan, Kesavan, Gaspar, John Antonydas, Roskams, Tania ORCID: 0000-0002-2816-1530, Sachinidis, Agapios, Lagneaux, Laurence, Vanhaecke, Tamara ORCID: 0000-0002-6685-7299 and Rogiers, Vera ORCID: 0000-0003-0635-7740 (2012). Mesoderm-Derived Stem Cells: The Link Between the Transcriptome and Their Differentiation Potential. Stem Cells Dev., 21 (18). S. 3309 - 3324. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1557-8534

Doss, Michael Xavier and Sachinidis, Agapios (2019). Current Challenges of iPSC-Based Disease Modeling and Therapeutic Implications. Cells, 8 (5). BASEL: MDPI. ISSN 2073-4409

Dreser, Nadine ORCID: 0000-0002-7103-0990, Madjar, Katrin ORCID: 0000-0001-6169-8105, Holzer, Anna-Katharina, Kapitza, Marion, Scholz, Christopher, Kranaster, Petra ORCID: 0000-0002-6082-0161, Gutbier, Simon, Klima, Stefanie, Kolb, David, Dietz, Christian, Trefzer, Timo, Meisig, Johannes, van Thriel, Christoph ORCID: 0000-0003-3215-9262, Henry, Margit, Berthold, Michael R., Bluethgen, Nils, Sachinidis, Agapios, Rahnenfuehrer, Joerg, Hengstler, Jan G., Waldmann, Tanja and Leist, Marcel ORCID: 0000-0002-3778-8693 (2020). Development of a neural rosette formation assay (RoFA) to identify neurodevelopmental toxicants and to characterize their transcriptome disturbances. Arch. Toxicol., 94 (1). S. 151 - 172. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Edlund, Karolina, Madjar, Katrin, Lebrecht, Antje, Aktas, Bahriye ORCID: 0000-0002-5474-051X, Pilch, Henryk, Hoffmann, Gerald, Hofmann, Manfred, Kolberg, Hans-Christian, Boehm, Daniel, Battista, Marco, Seehase, Martina, Stewen, Kathrin, Gebhard, Susanne, Cadenas, Cristina, Marchan, Rosemarie, Brenner, Walburgis, Hasenburg, Annette, Koelbl, Heinz, Solbach, Christine, Gehrmann, Mathias, Tanner, Berno, Weber, Karsten E., Loibl, Sibylle, Sachinidis, Agapios, Rahnenfuehrer, Joerg, Schmidt, Marcus ORCID: 0000-0003-1365-2414 and Hengstler, Jan G. (2021). Gene Expression-Based Prediction of Neoadjuvant Chemotherapy Response in Early Breast Cancer: Results of the Prospective Multicenter EXPRESSION Trial. Clin. Cancer Res., 27 (8). S. 2148 - 2159. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Fernando, Ruani N., Chaudhari, Umesh ORCID: 0000-0002-7743-4371, Escher, Sylvia E., Hengstler, Jan G., Hescheler, Juergen, Jennings, Paul ORCID: 0000-0002-6860-2898, Keun, Hector C., Kleinjans, Jos C. S., Kolde, Raivo ORCID: 0000-0003-2886-6298, Kollipara, Laxmikanth, Kopp-Schneider, Annette, Limonciel, Alice ORCID: 0000-0001-6588-5944, Nemade, Harshal, Nguemo, Filomain, Peterson, Hedi ORCID: 0000-0001-9951-5116, Prieto, Pilar, Rodrigues, Robim M., Sachinidis, Agapios, Schaefer, Christoph, Sickmann, Albert ORCID: 0000-0002-2388-5265, Spitkovsky, Dimitry, Stoeber, Regina, van Breda, Simone G. J., van de Water, Bob, Vivier, Manon, Zahedi, Rene P., Vinken, Mathieu ORCID: 0000-0001-5115-8893 and Rogiers, Vera ORCID: 0000-0003-0635-7740 (2016). Watching the Detectives report of the general assembly of the EU project DETECTIVE Brussels, 24-25 November 2015. Arch. Toxicol., 90 (6). S. 1529 - 1540. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Filipova, Dilyana ORCID: 0000-0003-3532-9765, Henry, Margit, Rotshteyn, Tamara, Brunn, Anna, Carstov, Mariana, Deckert, Martina, Hescheler, Juergen, Sachinidis, Agapios, Pfitzer, Gabriele and Papadopoulos, Symeon (2018). Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Ca(v)1.1 converge at E18.5. PLoS One, 13 (3). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

Filipova, Dilyana ORCID: 0000-0003-3532-9765, Walter, Anna M., Gaspar, John A., Brunn, Anna, Linde, Nina F., Ardestani, Mostafa A., Deckert, Martina, Hescheler, Juergen, Pfitzer, Gabriele, Sachinidis, Agapios and Papadopoulos, Symeon (2016). Gene profiling of embryonic skeletal muscle lacking type I ryanodine receptor Ca2+ release channel. Sci Rep, 6. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

Frank, Stefan, Ahuja, Gaurav ORCID: 0000-0002-2837-9361, Bartsch, Deniz, Russ, Nicole, Yao, Wenjie, Kuo, Joseph Chao-Chung, Derks, Jens-Peter, Akhade, Vijay Suresh, Kargapolova, Yulia, Georgomanolis, Theodore, Messling, Jan-Erik ORCID: 0000-0003-3843-0041, Gramm, Marie, Brant, Lilija, Rehimi, Rizwan, Vargas, Natalia Emilse, Kuroczik, Alina, Yang, Tsun-Po, Sahito, Raja Ghazanfar Ali, Franzen, Julia, Hescheler, Juergen, Sachinidis, Agapios, Peifer, Martin, Rada-Iglesias, Alvaro ORCID: 0000-0001-7137-1341, Kanduri, Meena, Costa, Ivan G. ORCID: 0000-0003-2890-8697, Kanduri, Chandrasekhar, Papantonis, Argyris ORCID: 0000-0001-7551-1073 and Kurian, Leo ORCID: 0000-0001-7466-5169 (2019). yylncT Defines a Class of Divergently Transcribed lncRNAs and Safeguards the T-mediated Mesodermal Commitment of Human PSCs. Cell Stem Cell, 24 (2). S. 318 - 336. CAMBRIDGE: CELL PRESS. ISSN 1875-9777

Gaspar, John Antonydas, Doss, Michael Xavier, Hengstler, Jan Georg, Cadenas, Cristina, Hescheler, Juergen and Sachinidis, Agapios (2014). Unique Metabolic Features of Stem Cells, Cardiomyocytes, and Their Progenitors. Circ.Res., 114 (8). S. 1346 - 1361. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1524-4571

Gaspar, John Antonydas, Srinivasan, Sureshkumar Perumal, Sureshkumar, Poornima, Doss, Michael Xavier, Hescheler, Juergen, Papadopoulos, Symeon and Sachinidis, Agapios (2017). Depletion of Mageb16 induces differentiation of pluripotent stem cells predominantly into mesodermal derivatives. Sci Rep, 7. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

Ghallab, Ahmed ORCID: 0000-0003-0695-3403, Celliere, Geraldine, Henkel, Sebastian G., Driesch, Dominik, Hoehme, Stefan, Hofmann, Ute ORCID: 0000-0003-0823-9027, Zellmer, Sebastian, Godoy, Patricio, Sachinidis, Agapios, Blaszkewicz, Meinolf, Reif, Raymond, Marchan, Rosemarie ORCID: 0000-0003-4414-1633, Kuepfer, Lars ORCID: 0000-0002-8741-7786, Haeussinger, Dieter, Drasdo, Dirk, Gebhardt, Rolf and Hengstler, Jan G. (2016). Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases. J. Hepatol., 64 (4). S. 860 - 872. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1600-0641

Godoy, Patricio, Schmidt-Heck, Wolfgang, Natarajan, Karthick, Lucendo-Villarin, Baltasar, Szkolnicka, Dagmara ORCID: 0000-0003-1125-3575, Asplund, Annika, Bjorquist, Petter, Widera, Agata, Stober, Regina, Campos, Gisela, Hammad, Seddik ORCID: 0000-0003-0571-4208, Sachinidis, Agapios, Chaudhari, Umesh ORCID: 0000-0002-7743-4371, Damm, Georg, Weiss, Thomas S., Nuessler, Andreas, Synnergren, Jane ORCID: 0000-0003-4697-0590, Edlund, Karolina, Kueppers-Munther, Barbara, Hay, David C. and Hengstler, Jan G. (2015). Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells. J. Hepatol., 63 (4). S. 934 - 943. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1600-0641

Godoy, Patricio, Schmidt-Heck, Wolfgang, Natarajan, Karthick, Lucendo-Villarin, Baltasar, Szkolnicka, Dagmara ORCID: 0000-0003-1125-3575, Asplund, Annika, Bjorquist, Petter, Widera, Agata, Stoeber, Regina, Campos, Gisela, Hammad, Seddik, Sachinidis, Agapios, Chaudhari, Umesh, Damm, Georg, Weiss, Thomas S. ORCID: 0000-0003-0336-0581, Nuessler, Andreas, Synnergren, Jane ORCID: 0000-0003-4697-0590, Edlund, Karolina, Kuppers-Munther, Barbara, Hay, David C. and Hengstler, Jan G. (2016). Gene networks and transcription factor motifs defining the differentiation of human stem cells into hepatocyte-like cells (vol 63, pg 934, 2015). J. Hepatol., 64 (2). S. 525 - 527. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1600-0641

Godoy, Patricio, Widera, Agata, Schmidt-Heck, Wolfgang, Campos, Gisela, Meyer, Christoph, Cadenas, Cristina, Reif, Raymond, Stoeber, Regina, Hammad, Seddik, Puetter, Larissa, Gianmoena, Kathrin, Marchan, Rosemarie ORCID: 0000-0003-4414-1633, Ghallab, Ahmed ORCID: 0000-0003-0695-3403, Edlund, Karolina, Nuessler, Andreas, Thasler, Wolfgang E., Damm, Georg, Seehofer, Daniel, Weiss, Thomas S. ORCID: 0000-0003-0336-0581, Dirsch, Olaf, Dahmen, Uta, Gebhardt, Rolf, Chaudhari, Umesh ORCID: 0000-0002-7743-4371, Meganathan, Kesavan, Sachinidis, Agapios, Kelm, Jens, Hofmann, Ute ORCID: 0000-0003-0823-9027, Zahedi, Rene P., Guthke, Reinhard, Bluethgen, Nils, Dooley, Steven and Hengstler, Jan G. (2016). Gene network activity in cultivated primary hepatocytes is highly similar to diseased mammalian liver tissue. Arch. Toxicol., 90 (10). S. 2513 - 2530. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Grinberg, Marianna, Stoeber, Regina M., Albrecht, Wiebke, Edlund, Karolina, Schug, Markus, Godoy, Patricio, Cadenas, Cristina ORCID: 0000-0003-3374-6418, Marchan, Rosemarie, Lampen, Alfonso, Braeuning, Albert, Buhrke, Thorsten, Leist, Marcel ORCID: 0000-0002-3778-8693, Oberemm, Axel, Hellwig, Birte, Kamp, Hennicke, Gardner, Iain, Escher, Sylvia, Taboureau, Olivier, Aguayo-Orozco, Alejandro, Sachinidis, Agapios, Ellinger-Ziegelbauer, Heidrun, Rahnenfuehrer, Joerg and Hengstler, Jan G. (2018). Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes. Arch. Toxicol., 92 (12). S. 3517 - 3534. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Grinberg, Marianna, Stoeber, Regina M., Edlund, Karolina, Rempel, Eugen, Godoy, Patricio, Reif, Raymond, Widera, Agata, Madjar, Katrin, Schmidt-Heck, Wolfgang, Marchan, Rosemarie, Sachinidis, Agapios, Spitkovsky, Dimitry, Hescheler, Juergen, Carmo, Helena ORCID: 0000-0002-6650-5285, Arbo, Marcelo D., van de Water, Bob, Wink, Steven, Vinken, Mathieu ORCID: 0000-0001-5115-8893, Rogiers, Vera ORCID: 0000-0003-0635-7740, Escher, Sylvia, Hardy, Barry, Mitic, Dragana, Apic, Gordana, Myatt, Glenn, Waldmann, Tanja, Mardinoglu, Adil, Damm, Georg, Seehofer, Daniel, Nuessler, Andreas, Weiss, Thomas S. ORCID: 0000-0003-0336-0581, Oberemm, Axel, Lampen, Alfons, Schaap, Mirjam M., Luijten, Mirjam, van Steeg, Harry, Thasler, Wolfgang E., Kleinjans, Jos C. S., Stierum, Rob H., Leist, Marcel, Rahnenfuehrer, Joerg and Hengstler, Jan G. (2022). Toxicogenomics directory of chemically exposed human hepatocytes (vol 88, pg 2261, 2014). Arch. Toxicol., 96 (3). S. 945 - 947. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Grinberg, Marianna, Stoeber, Regina M., Edlund, Karolina, Rempel, Eugen, Godoy, Patricio, Reif, Raymond, Widera, Agata, Madjar, Katrin ORCID: 0000-0001-6169-8105, Schmidt-Heck, Wolfgang, Marchan, Rosemarie ORCID: 0000-0003-4414-1633, Sachinidis, Agapios, Spitkovsky, Dimitry, Hescheler, Jurgen, Carmo, Helena ORCID: 0000-0002-6650-5285, Arbo, Marcelo D., van de Water, Bob, Wink, Steven, Vinken, Mathieu ORCID: 0000-0001-5115-8893, Rogiers, Vera ORCID: 0000-0003-0635-7740, Escher, Sylvia, Hardy, Barry, Mitic, Dragana, Myatt, Glenn, Waldmann, Tanja, Mardinoglu, Adil, Damm, Georg ORCID: 0000-0002-2104-8076, Seehofer, Daniel, Nuessler, Andreas, Weiss, Thomas S., Oberemm, Axel ORCID: 0000-0002-4355-4404, Lampen, Alfons, Schaap, Mirjam M., Luijten, Mirjam, van Steeg, Harry, Thasler, Wolfgang E., Kleinjans, Jos C. S., Stierum, Rob H., Leist, Marcel ORCID: 0000-0002-3778-8693, Rahnenfuehrer, Joerg and Hengstler, Jan G. (2014). Toxicogenomics directory of chemically exposed human hepatocytes. Arch. Toxicol., 88 (12). S. 2261 - 2288. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Hamad, Sarkawt ORCID: 0000-0002-5155-9467, Derichsweiler, Daniel, Gaspar, John Antonydas, Brockmeier, Konrad, Hescheler, Juergen, Sachinidis, Agapios and Pfannkuche, Kurt Paul ORCID: 0000-0002-4284-774X (2022). High-efficient serum-free differentiation of endothelial cells from human iPS cells. Stem Cell Res. Ther., 13 (1). LONDON: BMC. ISSN 1757-6512

Hamad, Sarkawt ORCID: 0000-0002-5155-9467, Derichsweiler, Daniel, Papadopoulos, Symeon, Nguemo, Filomain, Saric, Tomo, Sachinidis, Agapios, Brockmeier, Konrad, Hescheler, Juergen, Boukens, Bastiaan J. and Pfannkuche, Kurt (2019). Generation of human induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer and scalable 3D suspension bioreactor cultures with reduced batch-to-batch variations. Theranostics, 9 (24). S. 7222 - 7239. LAKE HAVEN: IVYSPRING INT PUBL. ISSN 1838-7640

Hannes, Tobias ORCID: 0000-0002-8550-2282, Wolff, Marie, Doss, Michael Xavier, Pfannkuche, Kurt, Haustein, Moritz, Mueller-Ehmsen, Jochen, Sachinidis, Agapios, Hescheler, Juergen, Khalil, Markus and Halbach, Marcel (2015). Electrophysiological Characteristics of Embryonic Stem Cell-Derived Cardiomyocytes are Cell Line-Dependent. Cell. Physiol. Biochem., 35 (1). S. 305 - 315. BASEL: KARGER. ISSN 1421-9778

Hellweg, Christine E., Shinde, Vaibhav, Srinivasan, Sureshkumar Perumal, Henry, Margit, Rotshteyn, Tamara, Baumstark-Khan, Christa, Schmitz, Claudia, Feles, Sebastian, Spitta, Luis F., Hemmersbach, Ruth, Hescheler, Juergen and Sachinidis, Agapios (2020). Radiation Response of Murine Embryonic Stem Cells. Cells, 9 (7). BASEL: MDPI. ISSN 2073-4409

Heras-Bautista, Carlos O., Mikhael, Nelly, Lam, Jennifer, Shinde, Vaibhav, Katsen-Globa, Alisa, Dieluweit, Sabine, Molcanyi, Marek, Uvarov, Vladimir, Juetten, Peter, Sahito, Raja G. A., Mederos-Henry, Francisco, Piechot, Alexander, Brockmeier, Konrad, Hescheler, Juergen, Sachinidis, Agapios and Pfannkuche, Kurt (2019). Cardiomyocytes facing fibrotic conditions re-express extracellular matrix transcripts. Acta Biomater., 89. S. 180 - 193. OXFORD: ELSEVIER SCI LTD. ISSN 1878-7568

Hoelting, Lisa, Klima, Stefanie, Karreman, Christiaan, Grinberg, Marianna, Meisig, Johannes, Henry, Margit, Rotshteyn, Tamara, Rahnenfuehrer, Joerg, Bluethgen, Nils, Sachinidis, Agapios, Waldmann, Tanja and Leist, Marcel ORCID: 0000-0002-3778-8693 (2016). Stem Cell-Derived Immature Human Dorsal Root Ganglia Neurons to Identify Peripheral Neurotoxicants. Stem Cells Transl. Med., 5 (4). S. 476 - 488. HOBOKEN: WILEY. ISSN 2157-6580

Hombach, Andreas ORCID: 0000-0001-9328-8442, Barden, Markus, Hannappel, Lisa, Chmielewski, Markus, Rappl, Gunter, Sachinidis, Agapios and Abken, Hinrich (2022). IL12 integrated into the CAR exodomain converts CD8(+) T cells to poly-functional NK-like cells with superior killing of antigen-loss tumors. Mol. Ther., 30 (2). S. 593 - 606. CAMBRIDGE: CELL PRESS. ISSN 1525-0024

Khatri, Priti, Obernier, Kirsten ORCID: 0000-0002-4025-1299, Simeonova, Ina K., Hellwig, Andrea, Hoelzl-Wenig, Gabriele, Mandl, Claudia, Scholl, Catharina, Woelfl, Stefan, Winkler, Johannes, Gaspar, John A., Sachinidis, Agapios and Ciccolini, Francesca ORCID: 0000-0002-7276-7361 (2014). Proliferation and cilia dynamics in neural stem cells prospectively isolated from the SEZ. Sci Rep, 4. BERLIN: NATURE RESEARCH. ISSN 2045-2322

Kleiderman, Susanne, Sa, Joao V., Teixeira, Ana P., Brito, Catarina ORCID: 0000-0002-8926-279X, Gutbier, Simon, Evje, Lars G., Hadera, Mussie G., Glaab, Enrico ORCID: 0000-0003-3977-7469, Henry, Margit, Sachinidis, Agapios, Alves, Paula M., Sonnewald, Ursula and Leist, Marcel ORCID: 0000-0002-3778-8693 (2016). Functional and phenotypic differences of pure populations of stem cell-derived astrocytes and neuronal precursor cells. Glia, 64 (5). S. 695 - 716. HOBOKEN: WILEY. ISSN 1098-1136

Leist, Marcel ORCID: 0000-0002-3778-8693, Ringwald, Annette, Kolde, Raivo ORCID: 0000-0003-2886-6298, Bremer, Susanne, van Thriel, Christoph ORCID: 0000-0003-3215-9262, Krause, Karl-Heinz ORCID: 0000-0002-9033-6768, Rahnenfuehrer, Joerg, Sachinidis, Agapios, Hescheler, Juergen and Hengstler, Jan G. (2013). Test systems of developmental toxicity: state-of-the art and future perspectives. Arch. Toxicol., 87 (12). S. 2037 - 2043. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Li, Zhigang, Zhu, Huifang, Liu, Chang, Wang, Yumei, Wang, Duo, Liu, Huan, Cao, Wenze, Hu, Yi, Lin, Qin, Tong, Chang, Lu, Min, Sachinidis, Agapios, Li, Li and Peng, Luying (2019). GSK-3 beta inhibition protects the rat heart from the lipopolysaccharide-induced inflammation injury via suppressing FOXO3A activity. J. Cell. Mol. Med., 23 (11). S. 7796 - 7810. HOBOKEN: WILEY. ISSN 1582-4934

Limonciel, Alice, van Breda, Simone, Jiang, Xiaoqi, Tredwelll, Gregory D., Wilmes, Anja, Aschauer, Lydia, Theunissen, Daniel, Sachinidis, Agapios, de Kok, Theo, Keun, Hector C., Kopp-Schneider, Annette, Schrattenholz, Andre, Kleinjans, Jos and Jennings, Paul ORCID: 0000-0002-6860-2898 (2014). Integration of transcriptomic, epigenomic, proteomic and metabolomic data for the characterisation of the molecular response of renal epithelial cells to repeat-dose exposure to chemicals in vitro. Toxicol. Lett., 229. S. S230 - 1. CLARE: ELSEVIER IRELAND LTD. ISSN 1879-3169

Limonciel, Alice ORCID: 0000-0001-6588-5944, van Breda, Simone G., Jiang, Xiaoqi, Tredwell, Gregory D., Wilmes, Anja ORCID: 0000-0001-9485-4565, Aschauer, Lydia, Siskos, Alexandros P., Sachinidis, Agapios, Keun, Hector C., Kopp-Schneider, Annette, de Kok, Theo M., Kleinjans, Jos C. S. and Jennings, Paul ORCID: 0000-0002-6860-2898 (2018). Persistence of Epigenomic Effects After Recovery From Repeated Treatment With Two Nephrocarcinogens. Front. Genet., 9. LAUSANNE: FRONTIERS MEDIA SA. ISSN 1664-8021

Lundt, Andreas, Henseler, Christina, Wormuth, Carola, Soos, Julien, Seidel, Robin, Mueller, Ralf, Arshaad, Muhammad Imran, Broich, Karl, Hescheler, Juergen, Sachinidis, Agapios, Ehninger, Dan, Papazoglou, Anna and Weiergraeber, Marco (2018). Gender specific click and tone burst evoked ABR datasets from mice lacking the Ca(v)2.3 R-type voltage-gated calcium channel. Data Brief, 21. S. 1263 - 1267. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 2352-3409

Lundt, Andreas, Seidel, Robin, Soos, Julien, Henseler, Christina, Mueller, Ralf, Bakki, Maheshwar, Arshaad, Muhammad Imran, Ehninger, Dan, Hescheler, Juergen, Sachinidis, Agapios, Broich, Karl, Wormuth, Carola, Papazoglou, Anna and Weiergraeber, Marco (2019). Ca(v)3.2 T-Type Calcium Channels Are Physiologically Mandatory for the Auditory System. Neuroscience, 409. S. 81 - 101. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. ISSN 1873-7544

Lundt, Andreas, Soos, Julien, Henseler, Christina, Arshaad, Muhammad Imran, Mueller, Ralf, Ehninger, Dan, Hescheler, Juergen, Sachinidis, Agapios, Broich, Karl, Wormuth, Carole, Papazoglou, Anna and Weiergraeber, Marco (2019). Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice. J. Vis. Exp. (147). CAMBRIDGE: JOURNAL OF VISUALIZED EXPERIMENTS. ISSN 1940-087X

Lundt, Andreas, Soos, Julien, Seidel, Robin, Henseler, Christina, Mueller, Ralf, Ginde, Varun Raj, Arshaad, Muhammad Imran, Ehninger, Dan, Hescheler, Juergen, Sachinidis, Agapios, Broich, Karl, Wormuth, Carola, Papazoglou, Anna and Weiergraeber, Marco (2020). Functional implications of Ca(v)2.3 R-type voltage-gated calcium channels in the murine auditory system - novel vistas from brainstem-evoked response audiometry. Eur. J. Neurosci., 51 (7). S. 1583 - 1605. HOBOKEN: WILEY. ISSN 1460-9568

Machado, Rui, Sachinidis, Agapios and Futschik, Matthias E. (2021). Detection of Novel Potential Regulators of Stem Cell Differentiation and Cardiogenesis through Combined Genome-Wide Profiling of Protein-Coding Transcripts and microRNAs. Cells, 10 (9). BASEL: MDPI. ISSN 2073-4409

Meganathan, Kesavan, Sotiriadou, Isaia, Natarajan, Karthick, Hescheler, Juergen and Sachinidis, Agapios (2015). Signaling molecules, transcription growth factors and other regulators revealed from in-vivo and in-vitro models for the regulation of cardiac development. Int. J. Cardiol., 183. S. 117 - 129. CLARE: ELSEVIER IRELAND LTD. ISSN 1874-1754

Meganathan, Kesavan, Sotiriadou, Isaia, Natarajan, Karthick, Hescheler, Juergen and Sachinidis, Agapios (2015). Signaling molecules, transcription growth factors and other regulators revealed from in-vivo and in-vitro models for the regulation of cardiac development. Int. J. Cardiol., 183. S. 117 - 129. CLARE: ELSEVIER IRELAND LTD. ISSN 1874-1754

Nemade, Harshal, Acharya, Aviseka, Chaudhari, Umesh ORCID: 0000-0002-7743-4371, Nembo, Erastus, Nguemo, Filomain ORCID: 0000-0002-2236-6797, Riet, Nicole, Abken, Hinrich, Hescheler, Juergen, Papadopoulos, Symeon and Sachinidis, Agapios (2020). Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells. Cells, 9 (3). BASEL: MDPI. ISSN 2073-4409

Nemade, Harshal, Acharya, Aviseka, Chaudhari, Umesh, Nembo, Erastus, Nguemo, Filomain, Riet, Nicole, Abken, Hinrich, Hescheler, Jurgen, Papadopoulos, Symeon and Sachinidis, Agapios (2020). Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells (vol 9, 554, 2020). Cells, 9 (10). BASEL: MDPI. ISSN 2073-4409

Nemade, Harshal, Chaudhari, Umesh ORCID: 0000-0002-7743-4371, Acharya, Aviseka, Hescheler, Juergen, Hengstler, Jan Georg, Papadopoulos, Symeon and Sachinidis, Agapios (2018). Cell death mechanisms of the anti-cancer drug etoposide on human cardiomyocytes isolated from pluripotent stem cells. Arch. Toxicol., 92 (4). S. 1507 - 1525. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Pallocca, Giorgia, Grinberg, Marianna, Henry, Margit, Frickey, Tancred, Hengstler, Jan G., Waldmann, Tanja, Sachinidis, Agapios, Rahnenfuehrer, Joerg and Leist, Marcel ORCID: 0000-0002-3778-8693 (2016). Identification of transcriptome signatures and biomarkers specific for potential developmental toxicants inhibiting human neural crest cell migration. Arch. Toxicol., 90 (1). S. 159 - 181. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Pallocca, Giorgia, Nyffeler, Johanna ORCID: 0000-0002-6155-9743, Dolde, Xenia, Grinberg, Marianna, Gstraunthaler, Gerhard, Waldmann, Tanja, Rahnenfuehrer, Joerg, Sachinidis, Agapios and Leist, Marcel ORCID: 0000-0002-3778-8693 (2017). Impairment of human neural crest cell migration by prolonged exposure to interferon-beta. Arch. Toxicol., 91 (10). S. 3385 - 3403. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Papazoglou, Panagiota, Peng, Luying and Sachinidis, Agapios (2021). Epigenetic Mechanisms Involved in the Cardiovascular Toxicity of Anticancer Drugs. Front. Cardiovasc. Med., 8. LAUSANNE: FRONTIERS MEDIA SA. ISSN 2297-055X

Peinkofer, Gabriel, Maass, Martina, Pfannkuche, Kurt, Sachinidis, Agapios, Baldus, Stephan, Hescheler, Juergen, Saric, Tomo and Halbach, Marcel (2021). Persistence of intramyocardially transplanted murine induced pluripotent stem cell-derived cardiomyocytes from different developmental stages. Stem Cell Res. Ther., 12 (1). LONDON: BMC. ISSN 1757-6512

Pistollato, Francesca, Louisse, Jochem ORCID: 0000-0002-0517-2288, Scelfo, Bibiana ORCID: 0000-0002-2261-8683, Mennecozzi, Milena, Accordi, Benedetta, Basso, Giuseppe, Gaspar, John Antonydas, Zagoura, Dimitra, Barilari, Manuela, Palosaari, Taina, Sachinidis, Agapios and Bremer-Hoffmann, Susanne (2014). Development of a pluripotent stem cell derived neuronal model to identify chemically induced pathway perturbations in relation to neurotoxicity: Effects of CREB pathway inhibition. Toxicol. Appl. Pharmacol., 280 (2). S. 378 - 389. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE. ISSN 1096-0333

Rempel, Eugen, Hoelting, Lisa, Waldmann, Tanja, Balmer, Nina V., Schildknecht, Stefan, Grinberg, Marianna, Das Gaspar, John Antony, Shinde, Vaibhav, Stoeber, Regina, Marchan, Rosemarie ORCID: 0000-0003-4414-1633, van Thriel, Christoph ORCID: 0000-0003-3215-9262, Liebing, Julia ORCID: 0000-0002-3469-4616, Meisig, Johannes, Bluethgen, Nils, Sachinidis, Agapios, Rahnenfuehrer, Jorg, Hengstler, Jan G. and Leist, Marcel ORCID: 0000-0002-3778-8693 (2015). A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch. Toxicol., 89 (9). S. 1599 - 1619. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Rodrigues, Robim M., Branson, Steven, De Boe, Veerle, Sachinidis, Agapios, Rogiers, Vera ORCID: 0000-0003-0635-7740, De Kock, Joery ORCID: 0000-0002-4078-4896 and Vanhaecke, Tamara ORCID: 0000-0002-6685-7299 (2016). In vitro assessment of drug-induced liver steatosis based on human dermal stem cell-derived hepatic cells. Arch. Toxicol., 90 (3). S. 677 - 690. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Rodrigues, Robim M., Chaudhari, Umesh, Kollipara, Laxmikanth, Sachinidis, Agapios, Zahedi, Rene P., Sickmann, Albert ORCID: 0000-0002-2388-5265, Keun, Hector, Kopp-Schneider, Annette, Jiang, Xiaoqi, De Kock, Joery, Vanhaecke, Tamara, Rogiers, Vera M. and Vinken, Mathieu ORCID: 0000-0001-5115-8893 (2016). In vitro verification of an adverse outcome pathway of cholestasis. Hepatology, 64. S. 261A - 263. HOBOKEN: WILEY. ISSN 1527-3350

Rodrigues, Robim M., De Kock, Joery ORCID: 0000-0002-4078-4896, Branson, Steven, Vinken, Mathieu ORCID: 0000-0001-5115-8893, Meganathan, Kesavan, Chaudhari, Umesh ORCID: 0000-0002-7743-4371, Sachinidis, Agapios, Govaere, Olivier ORCID: 0000-0002-4426-6930, Roskams, Tania, De Boe, Veerle, Vanhaecke, Tamara ORCID: 0000-0002-6685-7299 and Rogiers, Vera ORCID: 0000-0003-0635-7740 (2014). Human Skin-Derived Stem Cells as a Novel Cell Source for In Vitro Hepatotoxicity Screening of Pharmaceuticals. Stem Cells Dev., 23 (1). S. 44 - 56. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1557-8534

Rodrigues, Robim M., Heymans, Anja, De Boe, Veerle, Sachinidis, Agapios, Chaudhari, Umesh ORCID: 0000-0002-7743-4371, Govaere, Olivier ORCID: 0000-0002-4426-6930, Roskams, Tania, Vanhaecke, Tamara ORCID: 0000-0002-6685-7299, Rogiers, Vera ORCID: 0000-0003-0635-7740 and De Kock, Joery ORCID: 0000-0002-4078-4896 (2016). Toxicogenomics-based prediction of acetaminophen-induced liver injury using human hepatic cell systems. Toxicol. Lett., 240 (1). S. 50 - 60. CLARE: ELSEVIER IRELAND LTD. ISSN 1879-3169

Rodrigues, Robim M., Kollipara, Laxmikanth, Chaudhari, Umesh ORCID: 0000-0002-7743-4371, Sachinidis, Agapios, Zahedi, Rene P., Sickmann, Albert ORCID: 0000-0002-2388-5265, Kopp-Schneider, Annette, Jiang, Xiaoqi, Keun, Hector, Hengstler, Jan, Oorts, Marlies, Annaert, Pieter, Hoeben, Eef, Gijbels, Eva ORCID: 0000-0002-7366-0769, De Kock, Joery ORCID: 0000-0002-4078-4896, Vanhaecke, Tamara ORCID: 0000-0002-6685-7299, Rogiers, Vera ORCID: 0000-0003-0635-7740 and Vinken, Mathieu ORCID: 0000-0001-5115-8893 (2018). Omics-based responses induced by bosentan in human hepatoma HepaRG cell cultures. Arch. Toxicol., 92 (6). S. 1939 - 1953. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Rodrigues, Robim M., Kollipara, Laxmikanth, Chaudhari, Umesh, Sachinidis, Agapios, Zahedi, Rene P., Sickmann, Albert, Kopp-Schneider, Annette, Jiang, Xiaoqi, Keun, Hector, Hengstler, Jan, Vanhalewyn, Tineke, De Kock, Joery, Vanhaecke, Tamara, Rogiers, Vera and Vinken, Mathieu ORCID: 0000-0001-5115-8893 (2017). Omics-based in vitro verification of an adverse outcome pathway of cholestatic liver injury. Toxicol. Lett., 280. S. S254 - 1. CLARE: ELSEVIER IRELAND LTD. ISSN 1879-3169

Rodrigues, Robim M., Sachinidis, Agapios, De Boe, Veerle, Rogiers, Vera ORCID: 0000-0003-0635-7740, Vanhaecke, Tamara ORCID: 0000-0002-6685-7299 and De Kock, Joery ORCID: 0000-0002-4078-4896 (2015). Identification of potential biomarkers of hepatitis B-induced acute liver failure using hepatic cells derived from human skin precursors. Toxicol. Vitro, 29 (6). S. 1231 - 1240. OXFORD: PERGAMON-ELSEVIER SCIENCE LTD. ISSN 0887-2333

Sabour, Davood, Machado, Rui S. R., Pinto, Jose P., Rohani, Susan, Sahito, Raja G. A., Hescheler, Jurgen, Futschik, Matthias E. and Sachinidis, Agapios (2018). Parallel Genome-wide Profiling of Coding and Non-coding RNAs to Identify Novel Regulatory Elements in Embryonic and Maturated Heart. Mol. Ther.-Nucl. Acids, 12. S. 158 - 174. CAMBRIDGE: CELL PRESS. ISSN 2162-2531

Sabour, Davood, Srinivasan, Sureshkumar Perumal, Rohani, Susan, Wagh, Vilas, Gaspar, John Antonydas, Panek, Darius, Ardestani, Mostafa Abootorabi, Doss, Michael Xavier, Riet, Nicole, Abken, Hinrich, Hescheler, Juergen, Papadopoulos, Symeon and Sachinidis, Agapios (2017). STRIP2 Is Indispensable for the Onset of Embryonic Stem Cell Differentiation. Mol.Ther.-Methods Clin. Dev., 5. S. 116 - 130. CAMBRIDGE: CELL PRESS. ISSN 2329-0501

Sachinidis, Agapios (2020). Cardiotoxicity and Heart Failure: Lessons from Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Anticancer Drugs. Cells, 9 (4). BASEL: MDPI. ISSN 2073-4409

Sachinidis, Agapios (2016). HIGHLIGHT REPORT: CARDIOTOXICITY SCREENING. EXCLI J., 15. S. 163 - 166. DORTMUND: EXCLI JOURNAL MANAGING OFFICE. ISSN 1611-2156

Sachinidis, Agapios (2021). High-throughput base editing: a promising technology for precision medicine and drug discovery. Signal Transduct. Target. Ther., 6 (1). LONDON: SPRINGERNATURE. ISSN 2059-3635

Sachinidis, Agapios, Albrecht, Wiebke, Nell, Patrick ORCID: 0000-0002-1421-3248, Cherianidou, Anna, Hewitt, Nicola J., Edlund, Karolina and Hengstler, Jan G. (2019). Road Map for Development of Stem Cell-Based Alternative Test Methods. Trends Mol. Med, 25 (6). S. 470 - 482. OXFORD: ELSEVIER SCI LTD. ISSN 1471-499X

Sahito, Raja Ghazanfar Ali, Sureshkumar, Poornima, Sotiriadou, Isaia, Srinivasan, Sureshkumar Perumal, Sabour, Davood, Hescheler, Juergen, Pfannkuche, Kurt and Sachinidis, Agapios (2016). The Potential Application of Biomaterials in Cardiac Stem Cell Therapy. Curr. Med. Chem., 23 (6). S. 589 - 603. SHARJAH: BENTHAM SCIENCE PUBL LTD. ISSN 1875-533X

Santos, Joao M. A., Mendes-Silva, Leonardo, Afonso, Vanessa, Martins, Gil, Machado, Rui S. R., Lopes, Joao A., Cancela, Leonor, Futschik, Matthias E., Sachinidis, Agapios, Gavaia, Paulo ORCID: 0000-0002-9582-1957 and Braganca, Jose ORCID: 0000-0001-9566-400X (2019). Exogenous WNT5A and WNT11 proteins rescue CITED2 dysfunction in mouse embryonic stem cells and zebrafish morphants. Cell Death Dis., 10. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-4889

Schulz, Julia C., Stumpf, Patrick S., Katsen-Globa, Alisa, Sachinidis, Agapios, Hescheler, Juergen and Zimmermann, Heiko ORCID: 0000-0001-8595-1304 (2012). First steps towards the successful surface-based cultivation of human embryonic stem cells in hanging drop systems. Eng. Life Sci., 12 (6). S. 584 - 588. HOBOKEN: WILEY-BLACKWELL. ISSN 1618-0240

Seidel, Florian, Cherianidou, Anna, Kappenberg, Franziska ORCID: 0000-0001-8066-5333, Marta, Miriam, Dreser, Nadine, Blum, Jonathan ORCID: 0000-0002-2058-0511, Waldmann, Tanja, Bluthgen, Nils, Meisig, Johannes, Madjar, Katrin ORCID: 0000-0001-6169-8105, Henry, Margit, Rotshteyn, Tamara, Scholtz-Illigens, Andreas, Marchan, Rosemarie, Edlund, Karolina, Leist, Marcel ORCID: 0000-0002-3778-8693, Rahnenfuehrer, Joerg, Sachinidis, Agapios and Hengstler, Jan Georg (2022). High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Differentiation. Cells, 11 (21). BASEL: MDPI. ISSN 2073-4409

Shinde, Vaibhav, Brungs, Sonja, Henry, Margit, Wegener, Lucia, Nemade, Harshal, Rotshteyn, Tamara, Acharya, Aviseka, Baumstark-Khan, Christa, Hellweg, Christine E., Hescheler, Juergen, Hemmersbach, Ruth and Sachinidis, Agapios (2016). Simulated Microgravity Modulates Differentiation Processes of Embryonic Stem Cells. Cell. Physiol. Biochem., 38 (4). S. 1483 - 1500. BASEL: KARGER. ISSN 1421-9778

Shinde, Vaibhav, Brungs, Sonja, Hescheler, Juergen, Hemmersbach, Ruth and Sachinidis, Agapios (2016). Pipette-based Method to Study Embryoid Body Formation Derived from Mouse and Human Pluripotent Stem Cells Partially Recapitulating Early Embryonic Development Under Simulated Microgravity Conditions. Microgravity Sci. Technol., 28 (3). S. 287 - 296. NEW YORK: SPRINGER. ISSN 1875-0494

Shinde, Vaibhav, Hoelting, Lisa, Srinivasan, Sureshkumar Perumal, Meisig, Johannes, Meganathan, Kesavan, Jagtap, Smita, Grinberg, Marianna, Liebing, Julia, Bluethgen, Nils, Rahnenfuehrer, Joerg, Rempel, Eugen, Stoeber, Regina, Schildknecht, Stefan, Foerster, Sunniva, Godoy, Patricio, van Thriel, Christoph ORCID: 0000-0003-3215-9262, Gaspar, John Antonydas, Hescheler, Juergen, Waldmann, Tanja, Hengstler, Jan G., Leist, Marcel ORCID: 0000-0002-3778-8693 and Sachinidis, Agapios (2017). Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Tox(ukn) and STOP-Tox(ukk) tests. Arch. Toxicol., 91 (2). S. 839 - 865. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Shinde, Vaibhav, Srinivasan, Sureshkumar Perumal, Henry, Margit, Rotshteyn, Tamara, Hescheler, Juergen, Rahnenfuehrer, Joerg, Grinberg, Marianna, Meisig, Johannes, Bluethgen, Nils, Waldmann, Tanja, Leist, Marcel ORCID: 0000-0002-3778-8693, Hengstler, Jan Georg and Sachinidis, Agapios (2016). Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells. Stem Cell Res. Ther., 7. LONDON: BMC. ISSN 1757-6512

Shinde, Vaibhav, Sureshkumar, Poornima, Sotiriadou, Isaia, Hescheler, Juergen and Sachinidis, Agapios (2016). Human Embryonic and Induced Pluripotent Stem Cell Based Toxicity Testing Models: Future Applications in New Drug Discovery. Curr. Med. Chem., 23 (30). S. 3495 - 3510. SHARJAH: BENTHAM SCIENCE PUBL LTD. ISSN 1875-533X

Simeon, Michael, Dangwal, Seema, Sachinidis, Agapios and Doss, Michael Xavier (2021). Application of the Pluripotent Stem Cells and Genomics in Cardiovascular Research-What We Have Learnt and Not Learnt until Now. Cells, 10 (11). BASEL: MDPI. ISSN 2073-4409

Spitkovsky, Dimitry, Lemke, Karen, Foerster, Tobias, Roemer, Robert, Wiedemeier, Stefan, Hescheler, Juergen, Sachinidis, Agapios and Gastrock, Gunter (2016). Generation of Cardiomyocytes in Pipe-Based Microbioreactor Under Segmented Flow. Cell. Physiol. Biochem., 38 (5). S. 1883 - 1897. BASEL: KARGER. ISSN 1421-9778

Srinivasan, Sureshkumar Perumal, Nemade, Harshal ORCID: 0000-0002-2704-181X, Cherianidou, Anna, Peng, Luying, Cruz-Molina, Sara, Rada-Iglesias, Alvaro ORCID: 0000-0001-7137-1341 and Sachinidis, Agapios (2022). Epigenetic mechanisms of Strip2 in differentiation of pluripotent stem cells. Cell Death Discov., 8 (1). LONDON: SPRINGERNATURE. ISSN 2058-7716

Storbeck, Markus, Hupperich, Kristina, Gaspar, John Antonydas, Meganathan, Kesavan, Carrera, Lilian Martinez, Wirth, Radu, Sachinidis, Agapios and Wirth, Brunhilde ORCID: 0000-0003-4051-5191 (2014). Neuronal-Specific Deficiency of the Splicing Factor Tra2b Causes Apoptosis in Neurogenic Areas of the Developing Mouse Brain. PLoS One, 9 (2). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

Sureshkumar, Poornima, Srinivasan, Sureshkumar Perumal, Natarajan, Karthick, Gaspar, John Antonydas, Hescheler, Juergen and Sachinidis, Agapios (2015). Stem cells and differentiation - a synoptic review of patents granted since 2009. Expert Opin. Ther. Patents, 25 (6). S. 663 - 674. ABINGDON: TAYLOR & FRANCIS LTD. ISSN 1744-7674

Waldmann, Tanja ORCID: 0000-0001-9276-1592, Grinberg, Marianna, Konig, Andre, Rempel, Eugen, Schildknecht, Stefan, Henry, Margit, Holzer, Anna-Katharina, Dreser, Nadine, Shinde, Vaibhav, Sachinidis, Agapios, Rahnenfuhrer, Jorg ORCID: 0000-0002-8947-440X, Hengstler, Jan G. and Leist, Marcel ORCID: 0000-0002-3778-8693 (2017). Stem Cell Transcriptome Responses and Corresponding Biomarkers That Indicate the Transition from Adaptive Responses to Cytotoxicity. Chem. Res. Toxicol., 30 (4). S. 905 - 923. WASHINGTON: AMER CHEMICAL SOC. ISSN 1520-5010

Waldmann, Tanja, Rempel, Eugen, Balmer, Nina V., Koenig, Andre, Kolde, Raivo ORCID: 0000-0003-2886-6298, Gaspar, John Antonydas, Henry, Margit, Hescheler, Juergen, Sachinidis, Agapios, Rahnenfuehrer, Joerg, Hengstler, Jan G. and Leist, Marcel ORCID: 0000-0002-3778-8693 (2014). Design Principles of Concentration-Dependent Transcriptome Deviations in Drug-Exposed Differentiating Stem Cells. Chem. Res. Toxicol., 27 (3). S. 408 - 421. WASHINGTON: AMER CHEMICAL SOC. ISSN 1520-5010

Wang, Duo, Liu, Chang, Liu, Huan, Meng, Yilei, Lin, Fang, Gu, Yanqiong, Wang, Hanrui, Shang, Mengyue, Tong, Chang, Sachinidis, Agapios, Ying, Qilong, Li, Li and Peng, Luying (2021). ERG1 plays an essential role in rat cardiomyocyte fate decision by mediating AKT signaling. Stem Cells, 39 (4). S. 443 - 458. HOBOKEN: WILEY. ISSN 1549-4918

Wang, Duo, Wang, Yumei, Liu, Huan, Tong, Chang, Ying, Qilong, Sachinidis, Agapios, Li, Li and Peng, Luying (2019). Laminin promotes differentiation of rat embryonic stem cells into cardiomyocytes by activating the integrin/FAK/PI3K p85 pathway. J. Cell. Mol. Med., 23 (5). S. 3629 - 3641. HOBOKEN: WILEY. ISSN 1582-4934

Weng, Matthias K., Natarajan, Karthick, Scholz, Diana, Ivanova, Violeta N., Sachinidis, Agapios, Hengstler, Jan G., Waldmann, Tanja and Leist, Marcel ORCID: 0000-0002-3778-8693 (2014). Lineage-Specific Regulation of Epigenetic Modifier Genes in Human Liver and Brain. PLoS One, 9 (7). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203