Universität zu Köln

Bebber, Christina M., Thomas, Emily S., Stroh, Jenny, Chen, Zhiyi, Androulidaki, Ariadne, Schmitt, Anna, Hoehne, Michaela N., Stueker, Lukas, Alves, Cleidson de Padua, Khonsari, Armin, Dammert, Marcel A., Parmaksiz, Fatma, Tumbrink, Hannah L., Beleggia, Filippo ORCID: 0000-0003-0234-7094, Sos, Martin L., Riemer, Jan, George, Julie, Brodesser, Susanne, Thomas, Roman K., Reinhardt, H. Christian and von Karstedt, Silvia (2021). Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes. Nat. Commun., 12 (1). BERLIN: NATURE RESEARCH. ISSN 2041-1723

Dammed, Marcel A., Bragelmann, Johannes, Olsen, Rachelle R., Boehm, Stefanie, Monhasery, Niloufar, Whitney, Christopher P., Chalishazar, Milind D., Tumbrink, Hannah L., Guthrie, Matthew R., Klein, Sebastian, Irelands, Abbie S., Ryan, Jeremy, Schmitt, Anna, Marx, Annika, Ozretic, Luka, Castiglione, Roberta ORCID: 0000-0002-9828-4405, Lorenz, Carina, Jachimowicz, Ron D., Wolf, Elmar ORCID: 0000-0002-5299-6335, Thomas, Roman K., Poirier, John T., Buettner, Reinhard, Sen, Triparna, Byers, Lauren A., Reinhardt, H. Christian, Letai, Anthony, Oliver, Trudy G. and Sos, Martin L. (2019). MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer. Nat. Commun., 10. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Dietlein, Felix, Kalb, Bastian, Jokic, Mladen, Noll, Elisa M., Strong, Alexander, Tharun, Lars, Ozretic, Luka, Kuenstlinger, Helen, Kambartel, Kato, Randerath, Winfried J., Juengst, Christian, Schmitt, Anna, Torgovnick, Alessandro, Richters, Andre, Rauh, Daniel ORCID: 0000-0002-1970-7642, Siedek, Florian, Persigehl, Thorsten, Mauch, Cornelia, Bartkova, Jirina, Bradley, Allan ORCID: 0000-0002-2349-8839, Sprick, Martin R. ORCID: 0000-0001-9691-7574, Trumpp, Andreas ORCID: 0000-0002-6212-3466, Rad, Roland, Saur, Dieter ORCID: 0000-0001-5874-0210, Bartek, Jiri, Wolf, Juergen, Buettner, Reinhard, Thomas, Roman K. and Reinhardt, H. Christian (2015). A Synergistic Interaction between Chk1-and MK2 Inhibitors in KRAS-Mutant Cancer. Cell, 162 (1). S. 146 - 160. CAMBRIDGE: CELL PRESS. ISSN 1097-4172

Doerr, Fabian, George, Julie, Schmitt, Anna, Beleggia, Filippo ORCID: 0000-0003-0234-7094, Rehkaemper, Tim, Hermann, Sarah, Walter, Vonn ORCID: 0000-0001-6114-6714, Weber, Jean-Philip, Thomas, Roman K., Wittersheim, Maike, Buettner, Reinhard, Persigehl, Thorsten and Reinhardt, H. Christian (2017). Targeting a non-oncogene addiction to the ATR/CHK1 axis for the treatment of small cell lung cancer. Sci Rep, 7. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

Erber, Johanna ORCID: 0000-0001-6614-6051, Steiner, Joachim D., Isensee, Joerg ORCID: 0000-0002-3390-0051, Lobbes, Leonard A., Toschka, Andre, Beleggia, Filippo ORCID: 0000-0003-0234-7094, Schmitt, Anna, Kaiser, Rainer W. J., Siedek, Florian, Persigehl, Thorsten, Hucho, Tim and Reinhardt, Hans C. (2019). Dual Inhibition of GLUT1 and the ATR/CHK1 Kinase Axis Displays Synergistic Cytotoxicity in KRAS-Mutant Cancer Cells. Cancer Res., 79 (19). S. 4855 - 4869. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Fassunke, Jana, Mueller, Fabienne, Keul, Marina, Michels, Sebastian, Dammert, Marcel A., Schmitt, Anna, Plenker, Dennis, Lategahn, Jonas ORCID: 0000-0001-5993-7082, Heydt, Carina, Braegelmann, Johannes, Tumbrink, Hannah L., Alber, Yannic, Klein, Sebastian, Heimsoeth, Alena, Dahmen, Ilona, Fischers, Rieke N., Scheffler, Matthias, Ihle, Michaela A., Priesner, Vanessa, Scheel, Andreas H., Wagener, Svenja, Kron, Anna, Frank, Konrad, Garbert, Katia, Persigehl, Thorsten, Puesken, Michael, Haneder, Stefan, Schaaf, Bernhard, Rodermann, Ernst, Engel-Riedel, Walburga, Felip, Enriqueta, Smit, Egbert F., Merkelbach-Bruse, Sabine, Reinhardt, H. Christian, Kast, Stefan M., Wolf, Juergen, Rauh, Daniel, Buettner, Reinhard and Sos, Martin L. (2018). Overcoming EGFR(G724S)-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors. Nat. Commun., 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Herling, Carmen D., Abedpour, Nima, Weiss, Jonathan, Schmitt, Anna, Jachimowicz, Ron Daniel, Merkel, Olaf ORCID: 0000-0001-5089-344X, Cartolano, Maria, Oberbeck, Sebastian, Mayer, Petra, Berg, Valeska, Thomalla, Daniel, Kutsch, Nadine, Stiefelhagen, Marius, Cramer, Paula, Wendtner, Clemens-Martin ORCID: 0000-0003-2866-2260, Persigehl, Thorsten, Saleh, Andreas, Altmueller, Janine, Nuernberg, Peter, Pallasch, Christian, Achter, Viktor, Lang, Ulrich, Eichhorst, Barbara, Castiglione, Roberta ORCID: 0000-0002-9828-4405, Schaefer, Stephan C., Buettner, Reinhard, Kreuzer, Karl-Anton, Reinhardt, Hans Christian, Hallek, Michael, Frenzel, Lukas P. and Peifer, Martin ORCID: 0000-0002-5243-5503 (2018). Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia. Nat. Commun., 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Jachimowicz, Ron D., Beleggia, Filippo ORCID: 0000-0003-0234-7094, Isensee, Joerg ORCID: 0000-0002-3390-0051, Velpula, Bhagya Bhavana, Goergens, Jonas, Bustos, Matias A., Doll, Markus A., Shenoy, Anjana, Checa-Rodriguez, Cintia, Wiederstein, Janica Lea, Baranes-Bachar, Keren, Bartenhagen, Christoph, Hertwig, Falk ORCID: 0000-0003-4784-6516, Teper, Nizan, Nishi, Tomohiko, Schmitt, Anna, Distelmaier, Felix, Luedecke, Hermann-Josef, Albrecht, Beate, Krueger, Marcus ORCID: 0000-0003-2008-4582, Schumacher, Bjorn ORCID: 0000-0001-6097-5238, Geiger, Tamar, Hoon, Dave S. B., Huertas, Pablo ORCID: 0000-0002-1756-4449, Fischer, Matthias, Hucho, Tim, Peifer, Martin, Ziv, Yael, Reinhardt, H. Christian, Wieczorek, Dagmar and Shiloh, Yosef (2019). UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. Cell, 176 (3). S. 505 - 542. CAMBRIDGE: CELL PRESS. ISSN 1097-4172

Jokic, Mladen, Vlasic, Ignacija, Rinneburger, Miriam ORCID: 0000-0003-3980-931X, Kluemper, Niklas, Spiro, Judith, Vogel, Wenzel, Offermann, Anne, Kuempers, Christiane, Fritz, Christian, Schmitt, Anna, Riabinska, Arina, Wittersheim, Maike, Michels, Sebastian, Ozretic, Luka, Florin, Alexandra, Welcker, Daniela, Akyuz, Mehmet Deniz, Nowak, Michael, Erkel, Martin, Wolf, Juergen, Buettner, Reinhard, Schumacher, Bjoern, Thomale, Juergen, Persigehl, Thorsten, Maintz, David, Perner, Sven and Reinhardt, Hans Christian (2016). Ercc1 Deficiency Promotes Tumorigenesis and Increases Cisplatin Sensitivity in a Tp53 Context-Specific Manner. Mol. Cancer Res., 14 (11). S. 1110 - 1124. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3125

Knittel, Gero, Rehkaemper, Tim, Nieper, Pascal, Schmitt, Anna, Fluemann, Ruth and Reinhardt, H. Christian (2018). DNA damage pathways and B-cell lymphomagenesis. Curr. Opin. Hematol., 25 (4). S. 315 - 323. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1531-7048

Meder, Lydia ORCID: 0000-0002-9547-5812, Schuldt, Philipp, Thelen, Martin ORCID: 0000-0002-2785-9726, Schmitt, Anna, Dietlein, Felix, Klein, Sebastian, Borchmann, Sven, Wennhold, Kerstin, Vlasic, Ignacija, Oberbeck, Sebastian, Riedel, Richard, Florin, Alexandra, Golfmann, Kristina, Schloesser, Hans A., Odenthal, Margarete, Buettner, Reinhard, Wolf, Juergen, Hallek, Michael, Herling, Marco, von Bergwelt-Baildon, Michael, Reinhardt, H. Christian and Ullrich, Roland T. (2018). Combined VEGF and PD-L1 Blockade Displays Synergistic Treatment Effects in an Autochthonous Mouse Model of Small Cell Lung Cancer. Cancer Res., 78 (15). S. 4270 - 4282. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Perkhofer, Lukas, Schmitt, Anna, Carrasco, Maria Carolina Romero, Ihle, Michaela, Hampp, Stephanie, Ruess, Dietrich Alexander, Hessmann, Elisabeth, Russell, Ronan, Lechel, Andre, Azoitei, Ninel, Lin, Qiong, Liebau, Stefan ORCID: 0000-0003-0721-8187, Hohwieler, Meike, Bohnenberger, Hanibal, Lesina, Marina, Alguel, Hana, Gieldon, Laura, Schroeck, Evelin, Gaedcke, Jochen, Wagner, Martin, Wiesmueller, Lisa, Sipos, Bence, Seufferlein, Thomas, Reinhardt, Hans Christian, Frappart, Pierre-Olivier and Kleger, Alexander (2017). ATM Deficiency Generating Genomic Instability Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Therapy-Induced DNA Damage. Cancer Res., 77 (20). S. 5576 - 5591. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Riabinska, Arina, Lehrman, Daria, Jachimowicz, Ron Daniel, Knitter, Gero, Fritz, Christian, Schmitt, Anna, Geyer, Aenne, Heneweer, Carola, Wittersheim, Maike, Frenzel, Lukas P., Torgovnick, Alessandro, Wiederstein, Janica Lea, Wunderlich, Claudia Maria, Ortmann, Monika, Paillard, Arlette, Woessmann, Wilhelm, Borkhardt, Arndt, Burdach, Stefan, Hansmann, Martin-Leo, Rosenwald, Andreas, Perner, Sven, Mall, Gita, Klapper, Wolfram, Merseburg, Andrea, Krueger, Marcus ORCID: 0000-0003-2008-4582, Gruell, Holger, Persigehl, Thorsten, Wunderlich, Frank Thomas, Peifer, Martin, Utermoehlen, Olaf, Buettner, Reinhard, Beleggia, Filippo ORCID: 0000-0003-0234-7094 and Reinhardt, Hans Christian (2020). ATM activity in T cells is critical for immune surveillance of lymphoma in vivo. Leukemia, 34 (3). S. 771 - 787. LONDON: SPRINGERNATURE. ISSN 1476-5551

Schmitt, Anna, Feldmann, Georg, Zander, Thomas and Reinhardt, H. Christian (2018). Targeting Defects in the Cellular DNA Damage Response for the Treatment of Pancreatic Ductal Adenocarcinoma. Oncol. Res. Treat., 41 (10). S. 619 - 626. BASEL: KARGER. ISSN 2296-5262

Schmitt, Anna, Knittel, Gero, Welcker, Daniela, Yang, Tsun-Po ORCID: 0000-0002-9077-4434, George, Julie, Nowak, Michael, Leeser, Uschi, Buettner, Reinhard, Perner, Sven, Peifer, Martin ORCID: 0000-0002-5243-5503 and Reinhardt, Hans Christian (2017). ATM Deficiency Is Associated with Sensitivity to PARP1-and ATR Inhibitors in Lung Adenocarcinoma. Cancer Res., 77 (11). S. 3040 - 3057. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Torgovnick, Alessandro, Heger, Jan Michel, Liaki, Vasiliki, Isensee, Joerg ORCID: 0000-0002-3390-0051, Schmitt, Anna, Knittel, Gero, Riabinska, Arina, Beleggia, Filippo ORCID: 0000-0003-0234-7094, Laurien, Lucie, Leeser, Uschi, Juengst, Christian, Siedek, Florian, Vogel, Wenzel, Kluemper, Niklas, Nolte, Hendrik, Wittersheim, Maike, Tharun, Lars, Castiglione, Roberta ORCID: 0000-0002-9828-4405, Krueger, Marcus, Schauss, Astrid, Perner, Sven, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Buettner, Reinhard, Persigehl, Thorsten, Hucho, Tim, Herter-Sprie, Grit Sophie, Schumacher, Bjoern and Reinhardt, Hans Christian (2018). The Cdkn1a(SuPER) Mouse as a Tool to Study p53-Mediated Tumor Suppression. Cell Reports, 25 (4). S. 1027 - 1046. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

Welcker, Daniela, Jain, Manaswita ORCID: 0000-0002-5107-7505, Khurshid, Safiya ORCID: 0000-0003-1620-3091, Jokic, Mladen, Hoehne, Martin, Schmitt, Anna, Frommolt, Peter ORCID: 0000-0002-1966-8014, Niessen, Carien M., Spiro, Judith, Persigehl, Thorsten, Wittersheim, Maike, Buettner, Reinhard, Fanciulli, Maurizio, Schermer, Bernhard ORCID: 0000-0002-5194-9000, Reinhardt, Hans Christian, Benzing, Thomas and Hoepker, Katja (2018). AATF suppresses apoptosis, promotes proliferation and is critical for Kras-driven lung cancer. Oncogene, 37 (11). S. 1503 - 1519. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-5594

Werr, Lisa ORCID: 0000-0002-3697-4136, Plenker, Dennis, Dammert, Marcel A., Lorenz, Carina, Bragelmann, Johannes, Tumbrink, Hannah L., Klein, Sebastian, Schmitt, Anna, Buttner, Reinhard, Persigehl, Thorsten, Shokat, Kevan M., Wunderlich, F. Thomas, Schram, Alison M., Peifer, Martin ORCID: 0000-0002-5243-5503, Sos, Martin L., Reinhardt, H. Christian and Thomas, Roman K. (2022). CD74-NRG1 Fusions Are Oncogenic In Vivo and Induce Therapeutically Tractable ERBB2:ERBB3 Heterodimerization. Mol. Cancer Ther., 21 (5). S. 821 - 831. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-8514

Yang, Dian, Denny, Sarah K., Greenside, Peyton G., Chaikovsky, Andrea C., Brady, Jennifer J., Ouadah, Youcef, Granja, Jeffrey M., Jahchan, Nadine S., Lim, Jing Shan, Kwok, Shirley, Kong, Christina S., Berghoff, Anna S., Schmitt, Anna, Reinhardt, H. Christian, Park, Kwon-Sik, Preusser, Matthias, Kundaje, Anshul ORCID: 0000-0003-3084-2287, Greenleaf, William J., Sage, Julien and Winslow, Monte M. (2018). Intertumoral Heterogeneity in SCLC Is Influenced by the Cell Type of Origin. Cancer Discov., 8 (10). S. 1316 - 1332. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 2159-8290