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Journal Article
Engel, Julian, Richters, Andre, Getlik, Matthaeus, Tomassi, Stefano, Keul, Marina, Termathe, Martin ORCID: 0000-0002-5618-4633, Lategahn, Jonas
ORCID: 0000-0001-5993-7082, Becker, Christian, Mayer-Wrangowski, Svenja, Gruetter, Christian, Uhlenbrock, Niklas
ORCID: 0000-0002-4489-9535, Kruell, Jasmin, Schaumann, Niklas, Eppmann, Simone, Kibies, Patrick, Hoffgaard, Franziska, Heil, Jochen, Menninger, Sascha, Ortiz-Cuaran, Sandra, Heuckmann, Johannes M., Tinnefeld, Verena, Zahedi, Rene P., Sos, Martin L., Schultz-Fademrecht, Carsten, Thomas, Roman K., Kast, Stefan M. and Rauh, Daniel
ORCID: 0000-0002-1970-7642
(2015).
Targeting Drug Resistance in EGFR with Covalent Inhibitors: A Structure-Based Design Approach.
J. Med. Chem., 58 (17).
S. 6844 - 6864.
WASHINGTON:
AMER CHEMICAL SOC.
ISSN 1520-4804
Engel, Julian, Smith, Steven, Lategahn, Jonas ORCID: 0000-0001-5993-7082, Turnbrink, Hannah L., Goebel, Lisa, Becker, Christian, Hennes, Elisabeth, Keul, Marina, Unger, Anke, Mueller, Heiko, Baumann, Matthias, Schultz-Fademrecht, Carsten, Guenther, Georgia, Hengstler, Jan G. and Rauh, Daniel
(2017).
Structure-Guided Development of Covalent and Mutant-Selective Pyrazolopyrimidines to Target T790M Drug Resistance in Epidermal Growth Factor Receptor.
J. Med. Chem., 60 (18).
S. 7725 - 7745.
WASHINGTON:
AMER CHEMICAL SOC.
ISSN 1520-4804
Lategahn, Jonas ORCID: 0000-0001-5993-7082, Keul, Marina, Kloevekorn, Philip, Tumbrink, Hannah L., Niggenaber, Janina
ORCID: 0000-0003-2942-263X, Mueller, Matthias P., Hodson, Luke, Flasshoff, Maren, Hardick, Julia, Grabe, Tobias, Engel, Julian, Schultz-Fademrecht, Carsten, Baumann, Matthias, Ketzer, Julia, Muehlenberg, Thomas, Hiller, Wolf, Guenther, Georgia, Unger, Anke, Mueller, Heiko, Heimsoeth, Alena, Golz, Christopher, Blank-Landeshammer, Bernhard, Kollipara, Laxmikanth, Zahedi, Rene P., Strohmann, Carsten
ORCID: 0000-0002-4787-2135, Hengstler, Jan G., van Otterlo, Willem A. L., Bauer, Sebastian
ORCID: 0000-0001-5949-8120 and Rauh, Daniel
(2019).
Inhibition of osimertinib-resistant epidermal growth factor receptor EGFR-T790M/C797S.
Chem. Sci., 10 (46).
S. 10789 - 10802.
CAMBRIDGE:
ROYAL SOC CHEMISTRY.
ISSN 2041-6539
Lategahn, Jonas, Tumbrink, Hannah L., Schultz-Fademrecht, Carsten, Heimsoeth, Alena, Werr, Lisa ORCID: 0000-0002-3697-4136, Niggenaber, Janina, Keul, Marina, Parmaksiz, Fatma
ORCID: 0009-0003-3771-7128, Baumann, Matthias, Menninger, Sascha, Zent, Eldar, Landel, Ina, Weisner, Joern, Jeyakumar, Kirujan
ORCID: 0000-0002-0184-6775, Heyden, Leonie, Russ, Nicole, Mueller, Fabienne, Lorenz, Carina, Braegelmann, Johannes, Spille, Inga, Grabe, Tobias
ORCID: 0000-0002-8287-1971, Mueller, Matthias P., Heuckmann, Johannes M., Klebl, Bert M., Nussbaumer, Peter, Sos, Martin L. and Rauh, Daniel
(2022).
Insight into Targeting Exon20 Insertion Mutations of the Epidermal Growth Factor Receptor with Wild Type-Sparing Inhibitors.
J. Med. Chem., 65 (9).
S. 6643 - 6656.
WASHINGTON:
AMER CHEMICAL SOC.
ISSN 1520-4804