Universität zu Köln

Journal Article

Ackermann, Sandra ORCID: 0000-0002-5869-7344, Cartolano, Maria, Hero, Barbara, Welte, Anne, Kahlert, Yvonne, Roderwieser, Andrea, Bartenhagen, Christoph, Walter, Esther, Gecht, Judith, Kerschke, Laura, Volland, Ruth, Menon, Roopika, Heuckmann, Johannes M., Gartlgruber, Moritz, Hartlieb, Sabine ORCID: 0000-0003-3746-7010, Henrich, Kai-Oliver, Okonechnikov, Konstantin, Altmueller, Janine, Nuernberg, Peter, Lefever, Steve, de Wilde, Bram, Sand, Frederik, Ikram, Fakhera, Rosswog, Carolina, Fischer, Janina, Theissen, Jessica, Hertwig, Falk ORCID: 0000-0003-4784-6516, Singhi, Aatur D., Simon, Thorsten, Vogel, Wenzel, Perner, Sven, Krug, Barbara, Schmidt, Matthias, Rahmann, Sven, Achter, Viktor, Lang, Ulrich ORCID: 0000-0001-7166-0805, Vokuhl, Christian, Ortmann, Monika, Buettner, Reinhard, Eggert, Angelika, Speleman, Frank, O'Sullivan, Roderick J., Thomas, Roman K., Berthold, Frank, Vandesompele, Jo, Schramm, Alexander, Westermann, Frank, Schulte, Johannes H., Peifer, Martin and Fischer, Matthias (2018). A mechanistic classification of clinical phenotypes in neuroblastoma. Science, 362 (6419). S. 1165 - 1205. WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1095-9203

Carter, Daniel R., Murray, Jayne, Cheung, Belamy B., Gamble, Laura, Koach, Jessica, Tsang, Joanna, Sutton, Selina, Kalla, Heyam, Syed, Sarah, Gifford, Andrew J., Issaeva, Natalia ORCID: 0000-0001-5483-6610, Biktasova, Asel, Atmadibrata, Bernard, Sun, Yuting, Sokolowski, Nicolas, Ling, Dora, Kim, Patrick Y., Webber, Hannah, Clark, Ashleigh, Ruhle, Michelle, Liu, Bing, Oberthuer, Andre, Fischer, Matthias, Byrne, Jennifer, Saletta, Federica ORCID: 0000-0003-0598-3504, Thwe, Le Myo, Purmal, Andrei, Haderski, Gary, Burkhart, Catherine, Speleman, Frank, De Preter, Katleen, Beckers, Anneleen, Ziegler, David S., Liu, Tao ORCID: 0000-0001-6244-7316, Gurova, Katerina V., Gudkov, Andrei V., Norris, Murray D., Haber, Michelle ORCID: 0000-0003-2036-8817 and Marshall, Glenn M. (2015). Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma. Sci. Transl. Med., 7 (312). WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1946-6242

Depuydt, Pauline, Boeva, Valentina ORCID: 0000-0002-4382-7185, Hocking, Toby D., Cannoodt, Robrecht ORCID: 0000-0003-3641-729X, Ambros, Inge M., Ambros, Peter F. ORCID: 0000-0002-5507-7211, Asgharzadeh, Shahab, Attiyeh, Edward F., Combaret, Valerie, Defferrari, Raffaella, Fischer, Matthias, Hero, Barbara, Hogarty, Michael D., Irwin, Meredith S., Koster, Jan ORCID: 0000-0002-0890-7585, Kreissman, Susan, Ladenstein, Ruth, Lapouble, Eve, Laureys, Genevieve, London, Wendy B., Mazzocco, Katia ORCID: 0000-0002-6599-5681, Nakagawara, Akira, Noguera, Rosa, Ohira, Miki, Park, Julie R., Poetschger, Ulrike, Theissen, Jessica, Tonini, Gian Paolo, Valteau-Couanet, Dominique, Varesio, Luigi, Versteeg, Rogier ORCID: 0000-0001-7172-0388, Speleman, Frank, Maris, John M., Schleiermacher, Gudrun and De Preter, Katleen (2018). Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients. JNCI-J. Natl. Cancer Inst., 110 (10). CARY: OXFORD UNIV PRESS INC. ISSN 1460-2105

Dorneburg, Carmen, Fischer, Matthias, Barth, Thomas F. E., Mueller-Klieser, Wolfgang, Hero, Barbara, Gecht, Judith, Carter, Daniel R., de Preter, Katleen, Mayer, Benjamin, Christner, Lisa, Speleman, Frank, Marshall, Glenn M., Debatin, Klaus-Michael ORCID: 0000-0002-8397-1886 and Beltinger, Christian (2018). LDHA in Neuroblastoma Is Associated with Poor Outcome and Its Depletion Decreases Neuroblastoma Growth Independent of Aerobic Glycolysis. Clin. Cancer Res., 24 (22). S. 5772 - 5784. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Fabian, Johannes, Opitz, Desiree, Althoff, Kristina, Lodrini, Marco, Hero, Barbara, Volland, Ruth, Beckers, Anneleen, de Preter, Katleen, Decock, Anneleen ORCID: 0000-0002-1091-0927, Patil, Nitin, Abba, Mohammed, Kopp-Schneider, Annette, Astrahantseff, Kathy, Wuenschel, Jasmin, Pfeil, Sebastian, Ercu, Maria, Kuenkele, Annette, Hu, Jamie, Thole, Theresa, Schweizer, Leonille, Mechtersheimer, Gunhild, Carter, Daniel ORCID: 0000-0002-8464-238X, Cheung, Belamy B., Popanda, Odilia, v. Deimling, Andreas, Koster, Jan ORCID: 0000-0002-0890-7585, Versteeg, Rogier ORCID: 0000-0001-7172-0388, Schwab, Manfred, Marshall, Glenn M., Speleman, Frank, Erb, Ulrike, Zoeller, Margot, Allgayer, Heike, Simon, Thorsten, Fischer, Matthias, Kulozik, Andreas E., Eggert, Angelika, Witt, Olaf, Schulte, Johannes H. and Deubzer, Hedwig E. (2016). MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma. Oncotarget, 7 (41). S. 66344 - 66360. ORCHARD PARK: IMPACT JOURNALS LLC. ISSN 1949-2553

Henssen, Anton, Althoff, Kristina, Koche, Richard, Odersky, Andrea, Beckers, Anneleen, Speleman, Frank, Schaefers, Simon, De Preter, Katleen, Florin, Alexandra, Heukamp, Lukas, Spruessel, Annika, Astrahanseff, Kathy, Sadowski, Natalie, Schramm, Alexander, Eggert, Angelika, Astorgues-Xerri, Lucile, Riveiro, Eugenia, Cvitkovic, Esteban and Schulte, Johannes H. (2015). Targeting super-enhancer induced gene expression with the novel BRD4 inhibitor OTX015 in preclinical models of MYCN-amplified neuroblastoma. Cancer Res., 75. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Henssen, Anton ORCID: 0000-0003-1534-778X, Althoff, Kristina, Odersky, Andrea, Beckers, Anneleen, Koche, Richard ORCID: 0000-0002-6820-5083, Speleman, Frank, Schaefers, Simon, Bell, Emma, Nortmeyer, Maike, Westermann, Frank, De Preter, Katleen, Florin, Alexandra, Heukamp, Lukas ORCID: 0000-0002-3388-3482, Spruessel, Annika, Astrahanseff, Kathy, Lindner, Sven, Sadowski, Natalie, Schramm, Alexander ORCID: 0000-0001-7670-7529, Astorgues-Xerri, Lucile, Riveiro, Maria E., Eggert, Angelika, Cvitkovic, Esteban and Schulte, Johannes H. (2016). Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition. Clin. Cancer Res., 22 (10). S. 2470 - 2482. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Molenaar, Jan J., Domingo-Fernandez, Raquel, Ebus, Marli E., Lindner, Sven, Koster, Jan ORCID: 0000-0002-0890-7585, Drabek, Ksenija, Mestdagh, Pieter, van Sluis, Peter, Valentijn, Linda J., van Nes, Johan ORCID: 0000-0001-7691-1431, Broekmans, Marloes, Haneveld, Franciska, Volckmann, Richard, Bray, Isabella, Heukamp, Lukas ORCID: 0000-0002-3388-3482, Spruessel, Annika, Thor, Theresa, Kieckbusch, Kristina, Klein-Hitpass, Ludger, Fischer, Matthias, Vandesompele, Jo ORCID: 0000-0001-6274-0184, Schramm, Alexander ORCID: 0000-0001-7670-7529, van Noesel, Max M., Varesio, Luigi, Speleman, Frank, Eggert, Angelika ORCID: 0000-0003-3476-8184, Stallings, Raymond L., Caron, Huib N., Versteeg, Rogier ORCID: 0000-0001-7172-0388 and Schulte, Johannes H. (2012). LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression. Nature Genet., 44 (11). S. 1199 - 1207. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1546-1718

Moreno, Lucas, Barone, Giuseppe, DuBois, Steven G., Molenaar, Jan, Fischer, Matthias, Schulte, Johannes, Eggert, Angelika ORCID: 0000-0003-3476-8184, Schleiermacher, Gudrun, Speleman, Frank, Chesler, Louis, Geoerger, Birgit, Hogarty, Michael D., Irwin, Meredith S., Bird, Nick, Blanchard, Guy B., Buckland, Sean, Caron, Hubert, Davis, Susan, De Wilde, Bram, DeubZer, Hedwig E., Dolman, Emmy, Eilers, Martin, George, Rani E., George, Sally, Sterba, Jaroslav, Maris, John M., Marshall, Lynley, Merchant, Melinda, Mortimer, Peter, Owens, Cormac, Philpott, Anna, Poon, Evon, Shay, Jerry W., Tonelli, Roberto, Valteau-Couanet, Dominique, Vassal, Gilles, Park, Julie R. and Pearson, Andrew D. J. (2020). Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma. Eur. J. Cancer, 136. S. 52 - 69. OXFORD: ELSEVIER SCI LTD. ISSN 1879-0852

Mus, Liselot M., Lambertz, Irina, Claeys, Shana, Kumps, Candy, Van Loocke, Wouter, Van Neste, Christophe ORCID: 0000-0002-5958-5731, Umapathy, Ganesh, Vaapil, Marica, Bartenhagen, Christoph, Laureys, Genevieve, De Wever, Olivier, Bexell, Daniel, Fischer, Matthias, Hallberg, Bengt, Schulte, Johannes, De Wilde, Bram, Durinck, Kaat, Denecker, Geertrui, De Preter, Katleen and Speleman, Frank (2020). The ETS transcription factor ETV5 is a target of activated ALK in neuroblastoma contributing to increased tumour aggressiveness. Sci Rep, 10 (1). LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

Nunes, Carolina ORCID: 0000-0002-8564-6171, Depestel, Lisa ORCID: 0000-0001-5690-3258, Mus, Liselot, Keller, Kaylee M. ORCID: 0000-0002-3130-7465, Delhaye, Louis ORCID: 0000-0001-8876-7385, Louwagie, Amber ORCID: 0000-0003-1808-6749, Rishfi, Muhammad ORCID: 0000-0002-6386-4485, Whale, Alex, Kara, Neesha, Andrews, Simon R., Dela Cruz, Filemon, You, Daoqi, Siddiquee, Armaan, Cologna, Camila Takeno, De Craemer, Sam, Dolman, Emmy, Bartenhagen, Christoph, De Vloed, Fanny, Sanders, Ellen, Eggermont, Aline, Bekaert, Sarah-Lee ORCID: 0000-0002-4769-3460, Van Loocke, Wouter, Bek, Jan Willem ORCID: 0000-0003-1337-1970, Dewyn, Givani, Loontiens, Siebe ORCID: 0000-0002-4602-4580, Van Isterdael, Gert ORCID: 0000-0001-6626-1316, Decaesteker, Bieke, Tilleman, Laurentijn ORCID: 0000-0001-7584-1179, Van Nieuwerburgh, Filip ORCID: 0000-0001-8815-5485, Vermeirssen, Vanessa, Van Neste, Christophe, Ghesquiere, Bart ORCID: 0000-0003-1547-1705, Goossens, Steven, Eyckerman, Sven, De Preter, Katleen, Fischer, Matthias, Houseley, Jon, Molenaar, Jan, De Wilde, Bram ORCID: 0000-0003-0213-1322, Roberts, Stephen S., Durinck, Kaat ORCID: 0000-0003-1762-5739 and Speleman, Frank (2022). RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition. Sci. Adv., 8 (28). WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 2375-2548

Rombautd, Dries, Chiu, Hua-Sheng ORCID: 0000-0002-0296-5653, Decaesteker, Bieke, Everaert, Celine ORCID: 0000-0001-7772-4259, Yigit, Nurten, Peltier, Agathe, Janoueix, Isabelle, Bartenhagen, Christoph, Fischer, Matthias, Roberts, Stephen, D'Haene, Nicky, De Preter, Katleen, Speleman, Frank, Denecker, Geertrui, Sumazin, Pavel ORCID: 0000-0002-1215-4977, Vandesompele, Jo, Lefever, Steve and Mestdagh, Pieter (2019). Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes. Sci Rep, 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2045-2322

Zeka, Fjoralba, Decock, Anneleen ORCID: 0000-0002-1091-0927, Van Goethem, Alan, Vanderheyden, Katrien ORCID: 0000-0001-5934-0366, Demuynck, Fleur, Lammens, Tim, Helsmoortel, Hetty H., Vermeulen, Joelle, Noguera, Rosa, Berbegall, Ana P., Combaret, Valerie, Schleiermacher, Gudrun, Laureys, Genevieve, Schramm, Alexander, Schulte, Johannes H., Rahman, Sven, Bienertova-Vasku, Julie, Mazanek, Pavel, Jeison, Marta, Ash, Shifra, Hogarty, Michael D., Moreno-Smith, Mirthala, Barbieri, Eveline, Shohet, Jason, Berthold, Frank, Van Maerken, Tom, Speleman, Frank, Fischer, Matthias, De Preter, Katleen, Mestdagh, Pieter and Vandesompele, Jo (2018). Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients. JCI Insight, 3 (23). ANN ARBOR: AMER SOC CLINICAL INVESTIGATION INC. ISSN 2379-3708