Universität zu Köln

Journal Article

Androulidaki, Ariadne, Wachsmuth, Laurens, Polykratis, Apostolos ORCID: 0000-0001-6720-3302 and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2018). Differential role of MyD88 and TRIF signaling in myeloid cells in the pathogenesis of autoimmune diabetes. PLoS One, 13 (3). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

Dannappel, Marius, Vlantis, Katerina, Kumari, Snehlata, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Kim, Chun ORCID: 0000-0001-9497-708X, Wachsmuth, Laurens, Eftychi, Christina, Lin, Juan, Corona, Teresa, Hermance, Nicole, Zelic, Matija, Kirsch, Petra, Basic, Marijana, Bleich, Andre, Kelliher, Michelle and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2014). RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature, 513 (7516). S. 90 - 107. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Eftychi, Christina, Schwarzer, Robin, Vlantis, Katerina, Wachsmuth, Laurens, Basic, Marijana, Wagle, Prerana, Neurath, Markus F., Becker, Christoph, Bleich, Andre and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2019). Temporally Distinct Functions of the Cytokines IL-12 and IL-23 Drive Chronic Colon Inflammation in Response to Intestinal Barrier Impairment. Immunity, 51 (2). S. 367 - 385. CAMBRIDGE: CELL PRESS. ISSN 1097-4180

Graeb, Jessica, Suarez, Isabelle, van Gumpel, Edeltraud, Winter, Sandra, Schreiber, Fynn, Esser, Anna, Hoelscher, Christoph, Fritsch, Melanie, Herb, Marc ORCID: 0000-0002-7533-0288, Schramm, Michael, Wachsmuth, Laurens, Pallasch, Christian, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Kashkar, Hamid and Rybniker, Jan (2019). Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating mitochondrial membrane permeability transition. Nat. Commun., 10. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Hausmann, Annika ORCID: 0000-0001-8852-3444, Felmy, Boas, Kunz, Leo, Kroon, Sanne, Berthold, Dorothee Lisa, Ganz, Giverny, Sandu, Ioana, Nakamura, Toshihiro ORCID: 0000-0001-5051-4323, Zangger, Nathan Sebastien, Zhang, Yang, Dolowschiak, Tamas, Fattinger, Stefan Alexander, Furter, Markus, Mueller-Hauser, Anna Angelika, Barthel, Manja, Vlantis, Katerina, Wachsmuth, Laurens ORCID: 0000-0003-1701-9384, Kisielow, Jan ORCID: 0000-0002-4482-5202, Tortola, Luigi ORCID: 0000-0002-8480-2080, Heide, Danijela, Heikenwaelder, Mathias, Oxenius, Annette, Kopf, Manfred, Schroeder, Timm, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Sellin, Mikael Erik and Hardt, Wolf-Dietrich (2021). Intercrypt sentinel macrophages tune antibacterial NF-kappa B responses in gut epithelial cells via TNF. J. Exp. Med., 218 (11). NEW YORK: ROCKEFELLER UNIV PRESS. ISSN 1540-9538

Jiao, Huipeng, Wachsmuth, Laurens, Kumari, Snehlata, Schwarzer, Robin, Lin, Juan, Eren, Remzi Onur, Fisher, Amanda, Lane, Rebecca, Young, George R., Kassiotis, George, Kaiser, William J. and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2020). Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation. Nature, 580 (7803). S. 391 - 410. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Jiao, Huipeng ORCID: 0000-0001-9632-6176, Wachsmuth, Laurens, Wolf, Simone ORCID: 0000-0003-2073-8312, Lohmann, Juliane, Nagata, Masahiro, Kaya, Goeksu Goekberk, Oikonomou, Nikos, Kondylis, Vangelis ORCID: 0000-0002-6970-8731, Rogg, Manuel ORCID: 0000-0002-6658-9159, Diebold, Martin ORCID: 0000-0001-9636-6936, Troeder, Simon E., Zevnik, Branko, Prinz, Marco, Schell, Christoph ORCID: 0000-0001-5344-624X, Young, George R., Kassiotis, George and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2022). ADAR1 averts fatal type I interferon induction by ZBP1. Nature, 607 (7920). S. 776 - 804. BERLIN: NATURE PORTFOLIO. ISSN 1476-4687

Lalaoui, Najoua ORCID: 0000-0002-0165-3324, Boyden, Steven E., Oda, Hirotsugu, Wood, Geryl M., Stone, Deborah L., Chau, Diep, Liu, Lin, Stoffels, Monique, Kratina, Tobias, Lawlor, Kate E., Zaal, Kristien J. M., Hoffmann, Patrycja M., Etemadi, Nima, Shield-Artin, Kristy, Biben, Christine, Tsai, Wanxia Li, Blake, Mary D., Kuehn, Hye Sun, Yang, Dan, Anderton, Holly ORCID: 0000-0003-3913-9686, Silke, Natasha, Wachsmuth, Laurens, Zheng, Lixin, Moura, Natalia Sampaio, Beck, David B., Gutierrez-Cruz, Gustavo, Ombrello, Amanda K., Pinto-Patarroyo, Gineth P., Kueh, Andrew J., Herold, Marco J., Hall, Cathrine, Wang, Hongying, Chae, Jae Jin, Dmitrieva, Natalia I., McKenzie, Mark, Light, Amanda, Barham, Beverly K., Jones, Anne, Romeo, Tina M., Zhou, Qing, Aksentijevich, Ivona, Mullikin, James C., Gross, Andrew J., Shum, Anthony K., Hawkins, Edwin D., Masters, Seth L., Lenardo, Michael J., Boehm, Manfred, Rosenzweig, Sergio D., Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Voss, Anne K., Gadina, Massimo, Kastner, Daniel L. and Silke, John (2020). Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease. Nature, 577 (7788). S. 103 - 123. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Lin, Juan, Kumari, Snehlata, Kim, Chun ORCID: 0000-0001-9497-708X, Van, Trieu-My, Wachsmuth, Laurens, Polykratis, Apostolos ORCID: 0000-0001-6720-3302 and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2016). RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation. Nature, 540 (7631). S. 124 - 137. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Schwarzer, Robin, Jiao, Huipeng, Wachsmuth, Laurens, Tresch, Achim and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2020). FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells. Immunity, 52.

Schwarzer, Robin, Jiao, Huipeng ORCID: 0000-0001-9632-6176, Wachsmuth, Laurens ORCID: 0000-0003-1701-9384, Tresch, Achim ORCID: 0000-0002-4146-6371 and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2020). FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells. Immunity, 52 (6). 978-993.e6. Cell Press. ISSN 1074-7613

Strilic, Boris, Yang, Lida, Albarran-Juarez, Julian, Wachsmuth, Laurens, Han, Kang, Mueller, Ulrike C., Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Offermanns, Stefan ORCID: 0000-0001-8676-6805 (2016). Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis. Nature, 536 (7615). S. 215 - 235. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Thesis Abstract

Wachsmuth, Laurens (2015). Role of NF-κB mediated transcriptional regulation of Nfkbia/IκBα expression in vitro and in vivo. Thesis Abstract, Universität zu Köln.