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Anand, Ruchika ORCID: 0000-0001-7337-6007, Wai, Timothy
ORCID: 0000-0002-6770-6222, Baker, Michael J., Kladt, Nikolay, Schauss, Astrid C., Rugarli, Elena
ORCID: 0000-0002-5782-1067 and Langer, Thomas
ORCID: 0000-0003-1250-1462
(2014).
The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission.
J. Cell Biol., 204 (6).
S. 919 - 930.
NEW YORK:
ROCKEFELLER UNIV PRESS.
ISSN 1540-8140
Cretin, Emma, Lopes, Priscilla, Vimont, Elodie, Tatsuta, Takashi, Langer, Thomas, Gazi, Anastasia ORCID: 0000-0002-2922-3625, Sachse, Martin, Yu-Wai-Man, Patrick, Reynier, Pascal
ORCID: 0000-0003-0802-4608 and Wai, Timothy
ORCID: 0000-0002-6770-6222
(2021).
High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts.
EMBO Mol. Med., 13 (6).
HOBOKEN:
WILEY.
ISSN 1757-4684
Freyer, Christoph ORCID: 0000-0003-0418-1673, Cree, Lynsey M., Mourier, Arnaud, Stewart, James B., Koolmeister, Camilla, Milenkovic, Dusanka, Wai, Timothy
ORCID: 0000-0002-6770-6222, Floros, Vasileios I., Hagstrom, Erik, Chatzidaki, Emmanouella E., Wiesner, Rudolf J., Samuels, David C., Larsson, Nils-Goeran and Chinnery, Patrick F.
(2012).
Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission.
Nature Genet., 44 (11).
S. 1282 - 1286.
NEW YORK:
NATURE PUBLISHING GROUP.
ISSN 1546-1718
Hartmann, Bianca, Wai, Timothy ORCID: 0000-0002-6770-6222, Hu, Hao, MacVicar, Thomas, Musante, Luciana, Fischer-Zirnsak, Bjoern, Stenzel, Werner, Graef, Ralph, van den Heuvel, Lambert, Ropers, Hans-Hilger, Wienker, Thomas F., Huebner, Christoph, Langer, Thomas
ORCID: 0000-0003-1250-1462 and Kaindl, Angela M.
(2016).
Homozygous YME1L1 Mutation Causes Mitochondriopathy with Optic Atrophy and Mitochondrial Network Fragmentation.
eLife, 5.
CAMBRIDGE:
ELIFE SCIENCES PUBLICATIONS LTD.
ISSN 2050-084X
Hlynialuk, Christopher J., Ling, Binbing, Baker, Zakery N., Cobine, Paul A., Yu, Lisa D., Boulet, Aren, Wai, Timothy ORCID: 0000-0002-6770-6222, Hossain, Amzad, El Zawily, Amr M., McFie, Pamela J., Stone, Scot J., Diaz, Francisca, Moraes, Carlos T., Viswanathan, Deepa, Petris, Michael J. and Leary, Scot C.
(2015).
The Mitochondrial Metallochaperone SCO1 Is Required to Sustain Expression of the High-Affinity Copper Transporter CTR1 and Preserve Copper Homeostasis.
Cell Reports, 10 (6).
S. 933 - 944.
CAMBRIDGE:
CELL PRESS.
ISSN 2211-1247
Hlynialuk, Christopher J., Ling, Binbing, Baker, Zakery N., Cobine, Paul A., Yu, Lisa D., Boulet, Aren, Wai, Timothy ORCID: 0000-0002-6770-6222, Hossain, Amzad, El Zawily, Amr M., McFie, Pamela J., Stone, Scot J., Diaz, Francisca, Moraes, Carlos T., Viswanathan, Deepa, Petris, Michael J. and Leary, Scot C.
(2015).
The Mitochondrial Metallochaperone SCO1 Is Required to Sustain Expression of the High-Affinity Copper Transporter CTR1 and Preserve Copper Homeostasis.
Cell Reports, 10 (6).
S. 933 - 944.
CAMBRIDGE:
CELL PRESS.
ISSN 2211-1247
Hohl, Mathias, Ardehali, Hossein, Azuaje, Francisco J., Breckenridge, Ross A., Doehner, Wolfram ORCID: 0000-0001-7598-708X, Eaton, Philip
ORCID: 0000-0003-0748-2367, Ehret, Georg B., Fujita, Toshiro, Gaetani, Roberto
ORCID: 0000-0001-5667-5152, Giacca, Mauro
ORCID: 0000-0003-2927-7225, Hasenfuss, Gerd, Heymans, Stephane, Leite-Moreira, Adelino F.
ORCID: 0000-0001-7808-3596, Linke, Wolfgang A., Linz, Dominik
ORCID: 0000-0003-4893-0824, Lyon, Alexander, Mamas, Mamas A., Oresic, Matej
ORCID: 0000-0002-2856-9165, Papp, Zoltan, Pedrazzini, Thierry, Piepoli, Massimo, Prosser, Benjamin
ORCID: 0000-0003-3696-9131, Rizzuto, Rosario
ORCID: 0000-0001-7044-5097, Tarone, Guido, Tian, Rong
ORCID: 0000-0002-3676-3830, van Craenenbroeck, Emeline, van Rooij, Eva, Wai, Timothy
ORCID: 0000-0002-6770-6222, Weiss, Guenter
ORCID: 0000-0003-0709-2158 and Maack, Christoph
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(2014).
Meeting highlights from the 2013 European Society of Cardiology Heart Failure Association Winter Meeting on Translational Heart Failure Research.
Eur. J. Heart Fail., 16 (1).
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HOBOKEN:
WILEY.
ISSN 1879-0844
Lagouge, Marie, Mourier, Arnaud, Lee, Hyun Ju, Spahr, Henrik, Wai, Timothy ORCID: 0000-0002-6770-6222, Kukat, Christian
ORCID: 0000-0003-1508-0229, Ramos, Eduardo Silva, Motori, Elisa, Busch, Jakob D., Siira, Stefan
ORCID: 0000-0002-8391-0143, Kremmer, Elisabeth, Filipovska, Aleksandra
ORCID: 0000-0002-6998-8403 and Larsson, Nils-Goeran
(2015).
SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation.
PLoS Genet., 11 (8).
SAN FRANCISCO:
PUBLIC LIBRARY SCIENCE.
ISSN 1553-7404
Sprenger, Hans-Georg, Wani, Gulzar, Hesseling, Annika, Koenig, Tim, Patron, Maria, MacVicar, Thomas, Ahola, Sofia, Wai, Timothy, Barth, Esther, Rugarli, Elena I. ORCID: 0000-0002-5782-1067, Bergami, Matteo
ORCID: 0000-0001-5525-5025 and Langer, Thomas
(2019).
Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy.
EMBO Mol. Med., 11 (1).
HOBOKEN:
WILEY.
ISSN 1757-4684
Wai, Timothy, Garcia-Prieto, Jaime, Baker, Michael J., Merkwirth, Carsten, Benit, Paule, Rustin, Pierre, Javier Ruperez, Francisco, Barbas, Coral ORCID: 0000-0003-4722-491X, Ibanez, Borja and Langer, Thomas
(2016).
Heart failure caused by imbalanced OPA1 processing and mitochondrial fragmentation can be rescued by metabolic intervention.
Mitochondrion, 31.
S. 91 - 93.
OXFORD:
ELSEVIER SCI LTD.
ISSN 1872-8278
Wai, Timothy ORCID: 0000-0002-6770-6222, Garcia-Prieto, Jaime, Baker, Michael J., Merkwirth, Carsten
ORCID: 0000-0001-8895-3495, Benit, Paule, Rustin, Pierre, Javier Ruperez, Francisco, Barbas, Coral
ORCID: 0000-0003-4722-491X, Ibanez, Borja
ORCID: 0000-0002-5036-254X and Langer, Thomas
ORCID: 0000-0003-1250-1462
(2015).
Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice.
Science, 350 (6265).
WASHINGTON:
AMER ASSOC ADVANCEMENT SCIENCE.
ISSN 1095-9203
Wai, Timothy ORCID: 0000-0002-6770-6222 and Langer, Thomas
ORCID: 0000-0003-1250-1462
(2016).
Mitochondrial Dynamics and Metabolic Regulation.
Trends Endocrinol. Metab., 27 (2).
S. 105 - 118.
LONDON:
ELSEVIER SCIENCE LONDON.
ISSN 1879-3061
Wai, Timothy ORCID: 0000-0002-6770-6222, Saita, Shotaro
ORCID: 0000-0002-7406-8361, Nolte, Hendrik, Mueller, Sebastian, Koenig, Tim, Richter-Dennerlein, Ricarda, Sprenger, Hans-Georg, Madrenas, Joaquin, Muehlmeister, Mareike, Brandt, Ulrich
ORCID: 0000-0003-1869-6811, Krueger, Marcus
ORCID: 0000-0003-2008-4582 and Langer, Thomas
(2016).
The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L.
EMBO Rep., 17 (12).
S. 1844 - 1857.
HOBOKEN:
WILEY.
ISSN 1469-3178