Universität zu Köln

2022

Cherianidou, Anna, Seidel, Florian ORCID: 0000-0002-4466-332X, Kappenberg, Franziska ORCID: 0000-0001-8066-5333, Dreser, Nadine, Blum, Jonathan ORCID: 0000-0002-2058-0511, Waldmann, Tanja ORCID: 0000-0001-9276-1592, Bluethgen, Nils, Meisig, Johannes, Madjar, Katrin ORCID: 0000-0001-6169-8105, Henry, Margit, Rotshteyn, Tamara, Marchan, Rosemarie, Edlund, Karolina, Leist, Marcel ORCID: 0000-0002-3778-8693, Rahnenfuhrer, Joerg, Sachinidis, Agapios and Hengstler, Jan G. (2022). Classification of Developmental Toxicants in a Human iPSC Transcriptomics-Based Test. Chem. Res. Toxicol., 35 (5). S. 760 - 774. WASHINGTON: AMER CHEMICAL SOC. ISSN 1520-5010

Grinberg, Marianna, Stoeber, Regina M., Edlund, Karolina, Rempel, Eugen, Godoy, Patricio, Reif, Raymond, Widera, Agata, Madjar, Katrin, Schmidt-Heck, Wolfgang, Marchan, Rosemarie, Sachinidis, Agapios, Spitkovsky, Dimitry, Hescheler, Juergen, Carmo, Helena ORCID: 0000-0002-6650-5285, Arbo, Marcelo D., van de Water, Bob, Wink, Steven, Vinken, Mathieu ORCID: 0000-0001-5115-8893, Rogiers, Vera ORCID: 0000-0003-0635-7740, Escher, Sylvia, Hardy, Barry, Mitic, Dragana, Apic, Gordana, Myatt, Glenn, Waldmann, Tanja, Mardinoglu, Adil, Damm, Georg, Seehofer, Daniel, Nuessler, Andreas, Weiss, Thomas S. ORCID: 0000-0003-0336-0581, Oberemm, Axel, Lampen, Alfons, Schaap, Mirjam M., Luijten, Mirjam, van Steeg, Harry, Thasler, Wolfgang E., Kleinjans, Jos C. S., Stierum, Rob H., Leist, Marcel, Rahnenfuehrer, Joerg and Hengstler, Jan G. (2022). Toxicogenomics directory of chemically exposed human hepatocytes (vol 88, pg 2261, 2014). Arch. Toxicol., 96 (3). S. 945 - 947. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Seidel, Florian, Cherianidou, Anna, Kappenberg, Franziska ORCID: 0000-0001-8066-5333, Marta, Miriam, Dreser, Nadine, Blum, Jonathan ORCID: 0000-0002-2058-0511, Waldmann, Tanja, Bluthgen, Nils, Meisig, Johannes, Madjar, Katrin ORCID: 0000-0001-6169-8105, Henry, Margit, Rotshteyn, Tamara, Scholtz-Illigens, Andreas, Marchan, Rosemarie, Edlund, Karolina, Leist, Marcel ORCID: 0000-0002-3778-8693, Rahnenfuehrer, Joerg, Sachinidis, Agapios and Hengstler, Jan Georg (2022). High Accuracy Classification of Developmental Toxicants by In Vitro Tests of Human Neuroepithelial and Cardiomyoblast Differentiation. Cells, 11 (21). BASEL: MDPI. ISSN 2073-4409

2020

Dreser, Nadine ORCID: 0000-0002-7103-0990, Madjar, Katrin ORCID: 0000-0001-6169-8105, Holzer, Anna-Katharina, Kapitza, Marion, Scholz, Christopher, Kranaster, Petra ORCID: 0000-0002-6082-0161, Gutbier, Simon, Klima, Stefanie, Kolb, David, Dietz, Christian, Trefzer, Timo, Meisig, Johannes, van Thriel, Christoph ORCID: 0000-0003-3215-9262, Henry, Margit, Berthold, Michael R., Bluethgen, Nils, Sachinidis, Agapios, Rahnenfuehrer, Joerg, Hengstler, Jan G., Waldmann, Tanja and Leist, Marcel ORCID: 0000-0002-3778-8693 (2020). Development of a neural rosette formation assay (RoFA) to identify neurodevelopmental toxicants and to characterize their transcriptome disturbances. Arch. Toxicol., 94 (1). S. 151 - 172. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

2017

Pallocca, Giorgia, Nyffeler, Johanna ORCID: 0000-0002-6155-9743, Dolde, Xenia, Grinberg, Marianna, Gstraunthaler, Gerhard, Waldmann, Tanja, Rahnenfuehrer, Joerg, Sachinidis, Agapios and Leist, Marcel ORCID: 0000-0002-3778-8693 (2017). Impairment of human neural crest cell migration by prolonged exposure to interferon-beta. Arch. Toxicol., 91 (10). S. 3385 - 3403. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Shinde, Vaibhav, Hoelting, Lisa, Srinivasan, Sureshkumar Perumal, Meisig, Johannes, Meganathan, Kesavan, Jagtap, Smita, Grinberg, Marianna, Liebing, Julia, Bluethgen, Nils, Rahnenfuehrer, Joerg, Rempel, Eugen, Stoeber, Regina, Schildknecht, Stefan, Foerster, Sunniva, Godoy, Patricio, van Thriel, Christoph ORCID: 0000-0003-3215-9262, Gaspar, John Antonydas, Hescheler, Juergen, Waldmann, Tanja, Hengstler, Jan G., Leist, Marcel ORCID: 0000-0002-3778-8693 and Sachinidis, Agapios (2017). Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Tox(ukn) and STOP-Tox(ukk) tests. Arch. Toxicol., 91 (2). S. 839 - 865. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Waldmann, Tanja ORCID: 0000-0001-9276-1592, Grinberg, Marianna, Konig, Andre, Rempel, Eugen, Schildknecht, Stefan, Henry, Margit, Holzer, Anna-Katharina, Dreser, Nadine, Shinde, Vaibhav, Sachinidis, Agapios, Rahnenfuhrer, Jorg ORCID: 0000-0002-8947-440X, Hengstler, Jan G. and Leist, Marcel ORCID: 0000-0002-3778-8693 (2017). Stem Cell Transcriptome Responses and Corresponding Biomarkers That Indicate the Transition from Adaptive Responses to Cytotoxicity. Chem. Res. Toxicol., 30 (4). S. 905 - 923. WASHINGTON: AMER CHEMICAL SOC. ISSN 1520-5010

2016

Hoelting, Lisa, Klima, Stefanie, Karreman, Christiaan, Grinberg, Marianna, Meisig, Johannes, Henry, Margit, Rotshteyn, Tamara, Rahnenfuehrer, Joerg, Bluethgen, Nils, Sachinidis, Agapios, Waldmann, Tanja and Leist, Marcel ORCID: 0000-0002-3778-8693 (2016). Stem Cell-Derived Immature Human Dorsal Root Ganglia Neurons to Identify Peripheral Neurotoxicants. Stem Cells Transl. Med., 5 (4). S. 476 - 488. HOBOKEN: WILEY. ISSN 2157-6580

Pallocca, Giorgia, Grinberg, Marianna, Henry, Margit, Frickey, Tancred, Hengstler, Jan G., Waldmann, Tanja, Sachinidis, Agapios, Rahnenfuehrer, Joerg and Leist, Marcel ORCID: 0000-0002-3778-8693 (2016). Identification of transcriptome signatures and biomarkers specific for potential developmental toxicants inhibiting human neural crest cell migration. Arch. Toxicol., 90 (1). S. 159 - 181. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Shinde, Vaibhav, Srinivasan, Sureshkumar Perumal, Henry, Margit, Rotshteyn, Tamara, Hescheler, Juergen, Rahnenfuehrer, Joerg, Grinberg, Marianna, Meisig, Johannes, Bluethgen, Nils, Waldmann, Tanja, Leist, Marcel ORCID: 0000-0002-3778-8693, Hengstler, Jan Georg and Sachinidis, Agapios (2016). Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells. Stem Cell Res. Ther., 7. LONDON: BMC. ISSN 1757-6512

2015

Rempel, Eugen, Hoelting, Lisa, Waldmann, Tanja, Balmer, Nina V., Schildknecht, Stefan, Grinberg, Marianna, Das Gaspar, John Antony, Shinde, Vaibhav, Stoeber, Regina, Marchan, Rosemarie ORCID: 0000-0003-4414-1633, van Thriel, Christoph ORCID: 0000-0003-3215-9262, Liebing, Julia ORCID: 0000-0002-3469-4616, Meisig, Johannes, Bluethgen, Nils, Sachinidis, Agapios, Rahnenfuehrer, Jorg, Hengstler, Jan G. and Leist, Marcel ORCID: 0000-0002-3778-8693 (2015). A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch. Toxicol., 89 (9). S. 1599 - 1619. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

2014

Balmer, Nina V., Klima, Stefanie, Rempel, Eugen, Ivanova, Violeta N., Kolde, Raivo ORCID: 0000-0003-2886-6298, Weng, Matthias K., Meganathan, Kesavan, Henry, Margit, Sachinidis, Agapios, Berthold, Michael R., Hengstler, Jan G., Rahnenfuhrer, Jorg ORCID: 0000-0002-8947-440X, Waldmann, Tanja and Leist, Marcel ORCID: 0000-0002-3778-8693 (2014). From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects. Arch. Toxicol., 88 (7). S. 1451 - 1469. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Grinberg, Marianna, Stoeber, Regina M., Edlund, Karolina, Rempel, Eugen, Godoy, Patricio, Reif, Raymond, Widera, Agata, Madjar, Katrin ORCID: 0000-0001-6169-8105, Schmidt-Heck, Wolfgang, Marchan, Rosemarie ORCID: 0000-0003-4414-1633, Sachinidis, Agapios, Spitkovsky, Dimitry, Hescheler, Jurgen, Carmo, Helena ORCID: 0000-0002-6650-5285, Arbo, Marcelo D., van de Water, Bob, Wink, Steven, Vinken, Mathieu ORCID: 0000-0001-5115-8893, Rogiers, Vera ORCID: 0000-0003-0635-7740, Escher, Sylvia, Hardy, Barry, Mitic, Dragana, Myatt, Glenn, Waldmann, Tanja, Mardinoglu, Adil, Damm, Georg ORCID: 0000-0002-2104-8076, Seehofer, Daniel, Nuessler, Andreas, Weiss, Thomas S., Oberemm, Axel ORCID: 0000-0002-4355-4404, Lampen, Alfons, Schaap, Mirjam M., Luijten, Mirjam, van Steeg, Harry, Thasler, Wolfgang E., Kleinjans, Jos C. S., Stierum, Rob H., Leist, Marcel ORCID: 0000-0002-3778-8693, Rahnenfuehrer, Joerg and Hengstler, Jan G. (2014). Toxicogenomics directory of chemically exposed human hepatocytes. Arch. Toxicol., 88 (12). S. 2261 - 2288. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0738

Waldmann, Tanja, Rempel, Eugen, Balmer, Nina V., Koenig, Andre, Kolde, Raivo ORCID: 0000-0003-2886-6298, Gaspar, John Antonydas, Henry, Margit, Hescheler, Juergen, Sachinidis, Agapios, Rahnenfuehrer, Joerg, Hengstler, Jan G. and Leist, Marcel ORCID: 0000-0002-3778-8693 (2014). Design Principles of Concentration-Dependent Transcriptome Deviations in Drug-Exposed Differentiating Stem Cells. Chem. Res. Toxicol., 27 (3). S. 408 - 421. WASHINGTON: AMER CHEMICAL SOC. ISSN 1520-5010

Weng, Matthias K., Natarajan, Karthick, Scholz, Diana, Ivanova, Violeta N., Sachinidis, Agapios, Hengstler, Jan G., Waldmann, Tanja and Leist, Marcel ORCID: 0000-0002-3778-8693 (2014). Lineage-Specific Regulation of Epigenetic Modifier Genes in Human Liver and Brain. PLoS One, 9 (7). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

2012

Balmer, Nina V., Weng, Matthias K., Zimmer, Bastian ORCID: 0000-0003-0004-4890, Ivanova, Violeta N., Chambers, Stuart M., Nikolaeva, Elena, Jagtap, Smita, Sachinidis, Agapios, Hescheler, Juergen, Waldmann, Tanja ORCID: 0000-0001-9276-1592 and Leist, Marcel ORCID: 0000-0002-3778-8693 (2012). Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome. Hum. Mol. Genet., 21 (18). S. 4104 - 4115. OXFORD: OXFORD UNIV PRESS. ISSN 1460-2083