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Number of items: 28.

Journal Article

Asif, Maria, Kaygusuz, Emrah, Shinawi, Marwan, Nickelsen, Anna, Hsieh, Tzung-Chien, Wagle, Prerana, Budde, Birgit S., Hochscherf, Jennifer ORCID: 0000-0002-4412-7391, Abdullah, Uzma, Honing, Stefan, Nienberg, Christian, Lindenblatt, Dirk, Noegel, Angelika A., Altmuller, Janine ORCID: 0000-0003-4372-1521, Thiele, Holger, Motameny, Susanne, Fleischer, Nicole, Segal, Idan, Pais, Lynn, Tinschert, Sigrid, Samra, Nadra Nasser, Savatt, Juliann M., Rudy, Natasha L., De Luca, Chiara, Fortugno, Paola, White, Susan M., Krawitz, Peter, Hurst, Anna C. E., Niefind, Karsten ORCID: 0000-0002-0183-6315, Jose, Joachim ORCID: 0000-0002-0666-2676, Brancati, Francesco, Nurnberg, Peter and Hussain, Muhammad Sajid ORCID: 0000-0002-1353-8809 (2022). De novo variants of CSNK2B cause a new intellectual disability-craniodigital syndrome by disrupting the canonical Wnt signaling pathway. Hum. Genet. Genom. Adv., 3 (3). AMSTERDAM: ELSEVIER. ISSN 2666-2477

Lindenblatt, Dirk ORCID: 0000-0002-5561-1082, Applegate, Violetta ORCID: 0000-0003-4120-7983, Nickelsen, Anna, Klussmann, Merlin, Neundorf, Ines, Goetz, Claudia, Jose, Joachim ORCID: 0000-0002-0666-2676 and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2022). Molecular Plasticity of Crystalline CK2 alpha ' Leads to KN2, a Bivalent Inhibitor of Protein Kinase CK2 with Extraordinary Selectivity. J. Med. Chem., 65 (2). S. 1302 - 1313. WASHINGTON: AMER CHEMICAL SOC. ISSN 1520-4804

Werner, Christian, Gast, Alexander, Lindenblatt, Dirk, Nickelsen, Anna, Niefind, Karsten ORCID: 0000-0002-0183-6315, Jose, Joachim ORCID: 0000-0002-0666-2676 and Hochscherf, Jennifer ORCID: 0000-0002-4412-7391 (2022). Structural and Enzymological Evidence for an Altered Substrate Specificity in Okur-Chung Neurodevelopmental Syndrome Mutant CK2 alpha(Lys198Arg). Front. Mol. Biosci., 9. LAUSANNE: FRONTIERS MEDIA SA. ISSN 2296-889X

Schnitzler, Alexander and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2021). Structural basis for the design of bisubstrate inhibitors of protein kinase CK2 provided by complex structures with the substrate-competitive inhibitor heparin. Eur. J. Med. Chem., 214. ISSY-LES-MOULINEAUX: ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER. ISSN 1768-3254

Bakonyi, Daniel, Toelzer, Christine ORCID: 0000-0001-9984-5940, Stricker, Michael, Hummel, Werner, Niefind, Karsten ORCID: 0000-0002-0183-6315 and Groeger, Harald (2020). Expanding the Application Range of Microbial Oxidoreductases by an Alcohol Dehydrogenase from Comamonas testosteroni with a Broad Substrate Spectrum and pH Profile. Catalysts, 10 (11). BASEL: MDPI. ISSN 2073-4344

Lindenblatt, Dirk ORCID: 0000-0002-5561-1082, Nickelsen, Anna, Applegate, Violetta M., Jose, Joachim and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2020). Structural and Mechanistic Basis of the Inhibitory Potency of Selected 2-Aminothiazole Compounds on Protein Kinase CK2. J. Med. Chem., 63 (14). S. 7766 - 7773. WASHINGTON: AMER CHEMICAL SOC. ISSN 1520-4804

Pietsch, Markus, Viht, Kaido, Schnitzler, Alexander, Ekambaram, Ramesh, Steinkrueger, Michaela, Enkvist, Erki, Nienberg, Christian, Nickelsen, Anna, Lauwers, Miriam, Jose, Joachim, Uri, Asko and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2020). Unexpected CK2 beta-antagonistic functionality of bisubstrate inhibitors targeting protein kinase CK2. Bioorganic Chem., 96. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE. ISSN 1090-2120

Voss, Martin, Toelzer, Christine, Bhandari, Deepak D., Parker, Jane E. and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2019). Arabidopsis immunity regulator EDS1 in a PAD4/SAG101-unbound form is a monomer with an inherently inactive conformation. J. Struct. Biol., 208 (3). SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE. ISSN 1095-8657

Lindenblatt, Dirk ORCID: 0000-0002-5561-1082, Horn, Mareike, Goetz, Claudia, Niefind, Karsten ORCID: 0000-0002-0183-6315, Neundorf, Ines ORCID: 0000-0001-6450-3991 and Pietsch, Markus (2019). Design of CK2 beta-Mimicking Peptides as Tools To Study the CK2 alpha/CK2 beta Interaction in Cancer Cells. ChemMedChem, 14 (8). S. 833 - 842. WEINHEIM: WILEY-V C H VERLAG GMBH. ISSN 1860-7187

Lindenblatt, Dirk ORCID: 0000-0002-5561-1082, Nickelsen, Anna, Applegate, Violetta M., Hochscherf, Jennifer, Witulski, Benedict, Bouaziz, Zouhair, Marminon, Christelle ORCID: 0000-0002-4043-3949, Bretner, Maria, Le Borgne, Marc ORCID: 0000-0003-1398-075X, Jose, Joachim and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2019). Diacritic Binding of an Indenoindole Inhibitor by CK2 alpha Paralogs Explored by a Reliable Path to Atomic Resolution CK2 alpha ' Structures. ACS Omega, 4 (3). S. 5471 - 5479. WASHINGTON: AMER CHEMICAL SOC. ISSN 2470-1343

Bhandari, Deepak D., Lapin, Dmitry ORCID: 0000-0001-9591-3950, Kracher, Barbara, von Born, Patrick, Bautor, Jaqueline, Niefind, Karsten ORCID: 0000-0002-0183-6315 and Parker, Jane E. (2019). An EDS1 heterodimer signalling surface enforces timely reprogramming of immunity genes in Arabidopsis. Nat. Commun., 10. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Hochscherf, Jennifer ORCID: 0000-0002-4412-7391, Pietsch, Markus, Tieu, William ORCID: 0000-0002-7161-4152, Kuan, Kevin, Abell, Andrew D., Guetschow, Michael and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2018). Crystal structure of highly glycosylated human leukocyte elastase in complex with an S2 ' site binding inhibitor. Acta Crystallogr. F-Struct. Biol. Commun., 74. S. 480 - 490. CHESTER: INT UNION CRYSTALLOGRAPHY. ISSN 2053-230X

Pichlo, Christian ORCID: 0000-0002-3156-5667, Toelzer, Christine ORCID: 0000-0001-9984-5940, Chojnacki, Konrad ORCID: 0000-0002-9285-0904, Oecal, Sinan, Uthoff, Matthias ORCID: 0000-0002-6477-5505, Ruegenberg, Sabine, Hermanns, Thomas ORCID: 0000-0001-5350-7479, Schacherl, Magdalena ORCID: 0000-0002-5478-2509, Denzel, Martin S., Hofmann, Kay, Niefind, Karsten ORCID: 0000-0002-0183-6315 and Baumann, Ulrich (2018). Improved protein-crystal identification by using 2,2,2-trichloroethanol as a fluorescence enhancer. Acta Crystallogr. F-Struct. Biol. Commun., 74. S. 307 - 315. CHESTER: INT UNION CRYSTALLOGRAPHY. ISSN 2053-230X

Schnitzler, Alexander, Gratz, Andreas, Bollacke, Andre, Weyrich, Michael, Kucklaender, Uwe, Wuensch, Bernhard, Goetz, Claudia, Niefind, Karsten ORCID: 0000-0002-0183-6315 and Jose, Joachim (2018). A pi-Halogen Bond of Dibenzofuranones with the Gatekeeper Phe113 in Human Protein Kinase CK2 Leads to Potent Tight Binding Inhibitors. Pharmaceuticals, 11 (1). BASEL: MDPI. ISSN 1424-8247

Niefind, Karsten ORCID: 0000-0002-0183-6315, Bischoff, Nils, Golub, Andriy G., Bdzhola, Volodymyr G., Balanda, Anatoliy O., Prykhod'ko, Andriy O. and Yarmoluk, Sergiy M. (2017). Structural Hypervariability of the Two Human Protein Kinase CK2 Catalytic Subunit Paralogs Revealed by Complex Structures with a Flavonol- and a Thieno[2,3-d]pyrimidine-Based Inhibitor. Pharmaceuticals, 10 (1). BASEL: MDPI. ISSN 1424-8247

Hochscherf, Jennifer ORCID: 0000-0002-4412-7391, Lindenblatt, Dirk, Witulski, Benedict, Birus, Robin, Aichele, Dagmar, Marminon, Christelle ORCID: 0000-0002-4043-3949, Bouaziz, Zouhair, Le Borgne, Marc ORCID: 0000-0003-1398-075X, Jose, Joachim and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2017). Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2 alpha and Its Paralog CK2 alpha '. Pharmaceuticals, 10 (4). BASEL: MDPI. ISSN 1424-8247

Toelzer, Christine ORCID: 0000-0001-9984-5940, Pal, Sonia, Watzlawick, Hildegard, Altenbuchner, Josef and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2016). A novel esterase subfamily with alpha/beta-hydrolase fold suggested by structures of two bacterial enzymes homologous to L-homoserine O-acetyl transferases. FEBS Lett., 590 (1). S. 174 - 185. HOBOKEN: WILEY. ISSN 1873-3468

Hochscherf, Jennifer ORCID: 0000-0002-4412-7391, Lindenblatt, Dirk, Steinkrtiger, Michaela, Yoo, Eungyoung, Ulucan, Oezlem, Herzig, Stefan, Issinger, Olaf-Georg, Helms, Volkhard ORCID: 0000-0002-2180-9154, Goetz, Claudia, Neundorf, Ines ORCID: 0000-0001-6450-3991, Niefind, Karsten ORCID: 0000-0002-0183-6315 and Pietsch, Markus (2015). Development of a high-throughput screening-compatible assay to identify inhibitors of the CK2 alpha/CK2 beta interaction. Anal. Biochem., 468. S. 4 - 15. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE. ISSN 1096-0309

Guerra, Barbara ORCID: 0000-0003-1136-2413, Bischoff, Nils, Bdzhola, Volodymyr G., Yarmoluk, Sergiy M., Issinger, Olaf-Georg, Golub, Andriy G. and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2015). A Note of Caution on the Role of Halogen Bonds for Protein Kinase/Inhibitor Recognition Suggested by High- And Low-Salt CK2 alpha Complex Structures. ACS Chem. Biol., 10 (7). S. 1654 - 1661. WASHINGTON: AMER CHEMICAL SOC. ISSN 1554-8937

Guerra, Barbara ORCID: 0000-0003-1136-2413, Rasmussen, Tine D. L., Schnitzler, Alexander, Jensen, Hans H., Boldyreff, Brigitte S., Miyata, Yoshihiko, Marcussen, Niels, Niefind, Karsten ORCID: 0000-0002-0183-6315 and Issinger, Olaf-Georg (2015). Protein kinase CK2 inhibition is associated with the destabilization of HIF-1 alpha in human cancer cells. Cancer Lett., 356 (2). S. 751 - 762. CLARE: ELSEVIER IRELAND LTD. ISSN 1872-7980

Hubner, Gerda M., Larsen, Jane Nohr, Guerra, Barbara ORCID: 0000-0003-1136-2413, Niefind, Karsten ORCID: 0000-0002-0183-6315, Vrecl, Milka and Issinger, Olaf-Georg (2014). Evidence for aggregation of protein kinase CK2 in the cell: a novel strategy for studying CK2 holoenzyme interaction by BRET2. Mol. Cell. Biochem., 397 (1-2). S. 285 - 294. DORDRECHT: SPRINGER. ISSN 1573-4919

Guerra, Barbara, Rasmussen, Tine D. L., Schnitzler, Alexander, Jensen, Hans H., Boldyreff, Brigitte S., Miyata, Yoshihiko, Marcussen, Niels, Niefind, Karsten ORCID: 0000-0002-0183-6315 and Issinger, Olaf-Georg (2014). A NOVEL, SELECTIVE SMALL MOLECULE INHIBITOR OF PROTEIN KINASE CK2 INDUCES SIGNIFICANT CELL DEATH IN VITRO AND IN TUMOR XENOGRAFT MODELS. Anticancer Res., 34 (10). S. 5932 - 5933. ATHENS: INT INST ANTICANCER RESEARCH. ISSN 1791-7530

Schnitzler, Alexander, Olsen, Birgitte Brinkmann, Issinger, Olaf-Georg and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2014). The Protein Kinase CK2(Andante) Holoenzyme Structure Supports Proposed Models of Autoregulation and Trans-Autophosphorylation. J. Mol. Biol., 426 (9). S. 1871 - 1883. LONDON: ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD. ISSN 1089-8638

Hoeppner, Astrid ORCID: 0000-0002-7076-5936, Schomburg, Dietmar ORCID: 0000-0002-3354-822X and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2013). Enzyme-substrate complexes of the quinate/shikimate dehydrogenase from Corynebacterium glutamicum enable new insights in substrate and cofactor binding, specificity, and discrimination. Biol. Chem., 394 (11). S. 1505 - 1517. BERLIN: WALTER DE GRUYTER GMBH. ISSN 1437-4315

Wagner, Stephan ORCID: 0000-0001-5369-7911, Stuttmann, Johannes ORCID: 0000-0002-6207-094X, Rietz, Steffen, Guerois, Raphael, Brunstein, Elena, Bautor, Jaqueline, Niefind, Karsten ORCID: 0000-0002-0183-6315 and Parker, Jane E. (2013). Structural Basis for Signaling by Exclusive EDS1 Heteromeric Complexes with SAG101 or PAD4 in Plant Innate Immunity. Cell Host Microbe, 14 (6). S. 619 - 631. CAMBRIDGE: CELL PRESS. ISSN 1934-6069

Bischoff, Nils, Raaf, Jennifer, Olsen, Birgitte, Bretner, Maria ORCID: 0000-0002-9643-0843, Issinger, Olaf-Georg and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2011). Enzymatic activity with an incomplete catalytic spine: insights from a comparative structural analysis of human CK2 alpha and its paralogous isoform CK2 alpha'. Mol. Cell. Biochem., 356 (1-2). S. 57 - 66. DORDRECHT: SPRINGER. ISSN 1573-4919

Ahmed, Khalil, Issinger, Olaf-Georg and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2011). Protein kinase CK2: a catalyst for biology, medicine and structural biochemistry. Mol. Cell. Biochem., 356 (1-2). S. 1 - 4. DORDRECHT: SPRINGER. ISSN 0300-8177

Richter, Nina ORCID: 0000-0001-5109-0710, Breicha, Klaus, Hummel, Werner and Niefind, Karsten ORCID: 0000-0002-0183-6315 (2010). The Three-Dimensional Structure of AKR11B4, a Glycerol Dehydrogenase from Gluconobacter oxydans, Reveals a Tryptophan Residue as an Accelerator of Reaction Turnover. J. Mol. Biol., 404 (3). S. 353 - 363. LONDON: ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD. ISSN 1089-8638

This list was generated on Thu Mar 28 14:02:28 2024 CET.