Universität zu Köln

Thangarajah, Fabinshy, Treeter, Timo, Krug, Barbara, Hellmich, Martin, Eichler, Christian, Hanstein, Bettina, Mallmann, Peter and Malter, Wolfram (2019). Comparison of Subpectoral versus Prepectoral Immediate Implant Reconstruction after Skin- and Nipple-Sparing Mastectomy in Breast Cancer Patients: A Retrospective Hospital-Based Cohort Study. Breast Care, 14 (6). S. 382 - 388. BASEL: KARGER. ISSN 1661-3805

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Abstract

Introduction: Implant-based immediate breast reconstruction (IBR) is a common surgical procedure in breast cancer patients. Comparative analysis concerning the placement of implants is still lacking. Hence, we aimed to analyze pre- versus subpectoral IBR in breast cancer patients. Patients: A single-center experience with implant-based IBR following skin/nipple-sparing mastectomy was evaluated. Patient demographics, incidence of major complications, and quality of life assessed with BREAST-Q were compared between the pre- and subpectoral cohort. Results: A total of 63 patients were included in this analysis of whom 29 underwent subpectoral and 34 underwent prepectoral IBR. Median duration of surgery was prolonged in the subpectoral versus the prepectoral group (104 +/- 28 vs. 80 +/- 91 min; p < 0.05). The mean number of major complications was significantly increased in the subpectoral group (1.41 +/- 1.76 vs. 0.47 +/- 0.75 per patient; p < 0.05). Detailed analysis showed a significantly increased incidence of implant dislocation (p < 0.05) and a trend concerning capsular contracture (p = 0.086, not significant) and necrosis (p = 0.092, not significant) in the subpectoral group. Quality of life was equal in both groups. Conclusion: The mean number of major complications in the subpectoral group should be considered when IBR is indicated. Prepectoral IBR seems to be a feasible alternative surgical treatment option with less major complications in selected patients.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Thangarajah, Fabinshy UNSPECIFIED UNSPECIFIED UNSPECIFIED Treeter, Timo UNSPECIFIED UNSPECIFIED UNSPECIFIED Krug, Barbara UNSPECIFIED UNSPECIFIED UNSPECIFIED Hellmich, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Eichler, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Hanstein, Bettina UNSPECIFIED UNSPECIFIED UNSPECIFIED Mallmann, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Malter, Wolfram UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-125546
DOI:	10.1159/000496696
Journal or Publication Title:	Breast Care
Volume:	14
Number:	6
Page Range:	S. 382 - 388
Date:	2019
Publisher:	KARGER
Place of Publication:	BASEL
ISSN:	1661-3805
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SUBCUTANEOUS MASTECTOMY; REDUCING MASTECTOMY; OUTCOMES; BRA Multiple languages Oncology; Obstetrics & Gynecology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/12554