Universität zu Köln

Doepfner, Manfred, Dose, Christina, Breuer, Dieter, Heintz, Stefan, Schiffhauer, Stefanie and Banaschewski, Tobias . Efficacy of Omega-3/Omega-6 Fatty Acids in Preschool Children at Risk of ADHD: A Randomized Placebo-Controlled Trial. J. Atten. Disord.. THOUSAND OAKS: SAGE PUBLICATIONS INC. ISSN 1557-1246

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Abstract

Objective: To evaluate the efficacy of an Omega-3/Omega-6 fatty acid supplement in preschool children at risk for ADHD. Method: Forty preschool children with elevated levels of ADHD symptoms were randomly assigned to either a verum or a placebo group. Children in the verum group received a 4-month treatment with Omega-3/Omega-6 fatty acids. Outcome measures comprised parent- and teacher-rated ADHD symptoms, which were the primary outcome variables, internalizing and externalizing problems, and intellectual abilities. Results: Intention-to-treat analyses of covariance, controlling for age and baseline data, revealed effects on parent- and teacher-rated ADHD symptoms (primary outcomes; parent ratings: F = 4.51, df = 1, p = .04, d = 0.63; teacher ratings: F = 4.67, df = 1, p = .04, d = 0.70), parent-rated internalizing symptoms (F = 8.47, df = 1, p < .01, d = 0.63), and parent- and teacher-rated externalizing symptoms (parent ratings: F = 4.58, df = 1, p = .04, d = 0.54; teacher ratings: F = 5.99, df = 1, p = .02, d = 0.79). Analyses involving only cases with available data yielded significant moderate effects on teacher-rated inattention symptoms (F = 4.60, df = 1, p = .04, d = 0.79) and parent-rated internalizing problems (F = 6.04, df = 1, p = .02, d = 0.57). Conclusion: The intention-to-treat analyses provide some evidence for positive effects of Omega-3/Omega-6 fatty acids. However, the results require replication in larger samples to allow for firm conclusions for practice.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Doepfner, Manfred UNSPECIFIED UNSPECIFIED UNSPECIFIED Dose, Christina UNSPECIFIED UNSPECIFIED UNSPECIFIED Breuer, Dieter UNSPECIFIED UNSPECIFIED UNSPECIFIED Heintz, Stefan UNSPECIFIED UNSPECIFIED UNSPECIFIED Schiffhauer, Stefanie UNSPECIFIED UNSPECIFIED UNSPECIFIED Banaschewski, Tobias UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-128286
DOI:	10.1177/1087054719883023
Journal or Publication Title:	J. Atten. Disord.
Publisher:	SAGE PUBLICATIONS INC
Place of Publication:	THOUSAND OAKS
ISSN:	1557-1246
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; DEFICIT-HYPERACTIVITY DISORDER; BEHAVIOR PROBLEMS; SUPPLEMENTATION; METHYLPHENIDATE; IMMEDIATE; APPRAISAL; DIETARY; SAFETY Multiple languages Psychology, Developmental; Psychiatry Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/12828