Universität zu Köln

Azimzade, Youness and Saberi, Abbas Ali (2019). Short-range migration can alter evolutionary dynamics in solid tumors. J. Stat. Mech.-Theory Exp., 2019 (10). BRISTOL: IOP PUBLISHING LTD. ISSN 1742-5468

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Abstract

Here, we investigate how competition in the Eden model is affected by short range dispersal and the requirement that site updates occur only after several updates of the same site have been attempted previously. The latter models the effect of tissue or media resistance to invasion. We found that the existence of tissue intensifies Natural Selection and de-accelerating Genetic Drift, both to a limited extent. More interestingly, our results show that short-range migration can eliminate genetic demixing and conceal natural selection.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Azimzade, Youness UNSPECIFIED UNSPECIFIED UNSPECIFIED Saberi, Abbas Ali UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-132228
DOI:	10.1088/1742-5468/ab4983
Journal or Publication Title:	J. Stat. Mech.-Theory Exp.
Volume:	2019
Number:	10
Date:	2019
Publisher:	IOP PUBLISHING LTD
Place of Publication:	BRISTOL
ISSN:	1742-5468
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language GENOMIC INSTABILITY; NOISE-REDUCTION; CELL INVASION; GENETIC DRIFT; CANCER; MODELS; HETEROGENEITY; PATTERNS; MORPHOLOGY; DRIVEN Multiple languages Mechanics; Physics, Mathematical Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/13222