Universität zu Köln

Döpfner, Manfred ORCID: 0000-0002-7929-0463, Katzmann, Josepha, Hanisch, Charlotte, Fegert, Joerg M., Kölch, Michael, Ritschel, Anne, Treier, Anne-Katrin, Hellmich, Martin, Roessner, Veit ORCID: 0000-0002-1873-7081, Ravens-Sieberer, Ulrike, Banaschewski, Tobias ORCID: 0000-0003-4595-1144 and Görtz-Dorten, Anja (2019). Affective dysregulation in childhood-optimizing prevention and treatment: protocol of three randomized controlled trials in the ADOPT study. BMC Psychiatry, 19 (1). pp. 264-284. LONDON: BMC. ISSN 1471-244X

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Abstract

Background The terms affective dysregulation (AD) and irritability describe transdiagnostic dimensions and are characterized by an excessive reactivity to negative emotional stimuli with an affective (anger) and a behavioral component (aggression). Due to early onset, high prevalence and persistence, as well as developmental comorbidity, AD in childhood is one of the most psychosocially impairing and cost-intensive mental health conditions. AD is especially prevalent in children in the youth welfare service. Despite continuous research, there remains a substantial need for diagnostic approaches and optimization of individualized treatment strategies in order to improve outcomes and reduce the subjective and economic burden. Methods The ADOPT (Affective Dysregulation - Optimizing Prevention and Treatment) Consortium integrates internationally established, highly experienced and interdisciplinary research groups. The work program encompasses (a) epidemiology, including prevalence of symptoms and disorders, (b) development and evaluation of screening and assessment tools, (c) stepped care approaches for clinically useful personalized medicine, (d) evaluation of an easily accessible and cost-effective online intervention as indicated prevention (treatment effects, moderation/mediation analysis), and (e) evaluation of an intensive personalized modular outpatient treatment in a cohort of children with AD who live with their parents and in a cohort of children with AD who live in out-of-home care (treatment effects, moderation/mediation analysis). Discussion The results will lead to significant recommendations for improving treatment within routine clinical care in two cohorts of children with AD and coexisting conditions, especially oppositional-defiant disorder, conduct disorder and disruptive mood dysregulation disorder.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Döpfner, Manfred UNSPECIFIED orcid.org/0000-0002-7929-0463 UNSPECIFIED Katzmann, Josepha UNSPECIFIED UNSPECIFIED UNSPECIFIED Hanisch, Charlotte UNSPECIFIED UNSPECIFIED UNSPECIFIED Fegert, Joerg M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kölch, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Ritschel, Anne UNSPECIFIED UNSPECIFIED UNSPECIFIED Treier, Anne-Katrin UNSPECIFIED UNSPECIFIED UNSPECIFIED Hellmich, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Roessner, Veit UNSPECIFIED orcid.org/0000-0002-1873-7081 UNSPECIFIED Ravens-Sieberer, Ulrike UNSPECIFIED UNSPECIFIED UNSPECIFIED Banaschewski, Tobias UNSPECIFIED orcid.org/0000-0003-4595-1144 UNSPECIFIED Görtz-Dorten, Anja UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-141844
DOI:	10.1186/s12888-019-2239-8
Journal or Publication Title:	BMC Psychiatry
Volume:	19
Number:	1
Page Range:	pp. 264-284
Date:	2019
Publisher:	BMC
Place of Publication:	LONDON
ISSN:	1471-244X
Language:	English
Faculty:	Faculty of Human Sciences
Divisions:	Faculty of Human Sciences > Department Heilpädagogik und Rehabilitation Weitere Institute, Arbeits- und Forschungsgruppen > Interdisziplinäres Zentrum für empirische LehrerInnen- und Unterrichtsforschung (IZeF)
Subjects:	Psychology
Uncontrolled Keywords:	Keywords Language GUIDED SELF-HELP; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; EXTERNALIZING PROBLEM BEHAVIOR; CONDUCT PROBLEMS; FOLLOW-UP; PRESCHOOL-CHILDREN; ANGER MANAGEMENT; CLINICAL-TRIAL; INTERVENTIONS; PARENTS Multiple languages Psychiatry Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/14184