Wendtner, Clemens-Martin (2019). Ibrutinib: the home run for cure in CLL? Blood, 133 (19). S. 2003 - 2005. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

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Abstract

In this issue of Blood, Byrd et al report that after nearly 4 years of follow-up, there is an impressive and sustained progression-free survival and overall survival benefit to using the Bruton's tyrosine kinase inhibitor ibrutinib vs ofatumumab in patients with relapsed or refractory (r/r) chronic lymphocytic leukemia (CLL). Nevertheless, patients with specific high-risk features like TP53 or SF3B1 mutations showed a trend toward shorter progression-free survival, and altogether, only half of the enrolled patients were still receiving ibrutinib at the end of the observation period. 1

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Wendtner, Clemens-MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-148390
DOI: 10.1182/blood-2019-03-901090
Journal or Publication Title: Blood
Volume: 133
Number: 19
Page Range: S. 2003 - 2005
Date: 2019
Publisher: AMER SOC HEMATOLOGY
Place of Publication: WASHINGTON
ISSN: 1528-0020
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
RITUXIMABMultiple languages
HematologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/14839

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