Universität zu Köln

Augustin, Max, Horn, Carola, Koch, Julian, de Silva, Ute Sandaradura, Platten, Martin, Nierhoff, Dirk, Suarez, Isabelle, Chon, Seung-Hun ORCID: 0000-0002-8923-6428, Rybniker, Jan and Lehmann, Clara (2019). Short Communication: Tracking Tregs: Translocation of CD49b/LAG-3(+) Type 1 T Regulatory Cells to the Gut-Associated Lymphoid Tissue of HIV+ Patients. Aids Res. Hum. Retrovir., 35 (3). S. 247 - 251. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 1931-8405

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Abstract

The gastrointestinal mucosa [gut-associated lymphoid tissue (GALT)] represents the largest site of chronic immune activation and HIV replication. Important cellular agents in the immunopathogenesis of an HIV infection are, in particular, CD49b/LAG-3(+) type 1 T regulatory cells (Tr1), which secrete large amounts of IL-10 (interleukin-10), and plasmacytoid dendritic cells, the main producers of IFN-alpha (interferon-alpha). However, the distribution of CD49b/LAG-3(+) Tr1 cells along the GALT is unknown.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Augustin, Max UNSPECIFIED UNSPECIFIED UNSPECIFIED Horn, Carola UNSPECIFIED UNSPECIFIED UNSPECIFIED Koch, Julian UNSPECIFIED UNSPECIFIED UNSPECIFIED de Silva, Ute Sandaradura UNSPECIFIED UNSPECIFIED UNSPECIFIED Platten, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Nierhoff, Dirk UNSPECIFIED UNSPECIFIED UNSPECIFIED Suarez, Isabelle UNSPECIFIED UNSPECIFIED UNSPECIFIED Chon, Seung-Hun UNSPECIFIED orcid.org/0000-0002-8923-6428 UNSPECIFIED Rybniker, Jan UNSPECIFIED UNSPECIFIED UNSPECIFIED Lehmann, Clara UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-154763
DOI:	10.1089/aid.2018.0052
Journal or Publication Title:	Aids Res. Hum. Retrovir.
Volume:	35
Number:	3
Page Range:	S. 247 - 251
Date:	2019
Publisher:	MARY ANN LIEBERT, INC
Place of Publication:	NEW ROCHELLE
ISSN:	1931-8405
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language INCREASED FREQUENCY; ACTIVATION; INFECTION Multiple languages Immunology; Infectious Diseases; Virology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/15476