Benjamin, Chaigne, Alberto, Scire Carlo, Rosaria, Talarico, Tobias, Alexander, Zahir, Amoura, Tadej, Avcin, Lorenzo, Beretta, Andrea, Doria, Aurelien, Guffroy, Vera, Guimaraes, Eric, Hachulla, Thomas, Krieg, David, Launay, Gemma, Lepri, Pia, Moinzadeh, Ulf, Mueller-Ladner, Simona, Rednic, Ana, Rodrigues, Sander, Tas W., Van Vollenhoven, R. F., Ana, Vieira, Stefano, Bombardieri, Eurico, Fonseca Joao, Ilaria, Galetti, Matthias, Schneider, Vanessa, Smith, Maurizio, Cutolo, Marta, Mosca and Rebecca, Fischer-Betz (2018). Mixed connective tissue disease: state of the art on clinical practice guidelines. RMD Open, 4. LONDON: BMJ PUBLISHING GROUP. ISSN 2056-5933

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Abstract

Mixed connective tissue disease (MCTD) is a complex overlap disease with features of different autoimmune connective tissue diseases (CTDs) namely systemic sclerosis, poly/dermatomyositis and systemic lupus erythematous in patients with antibodies targeting the U1 small nuclear ribonucleoprotein particle. In this narrative review, we summarise the results of a systematic literature research which was performed as part of the European Reference Network on Rare and Complex Connective Tissue and Musculoskeletal Diseases project, aimed at evaluating existing clinical practice guidelines (CPGs) or recommendations. Since no specific CPGs on MCTD were found, other CPGs developed for other CTDs were taken into consideration in order to discuss what can be applied to MCTD even if designed for other diseases. Three major objectives were proposed for the future development of CPGs: MCTD diagnosis (diagnostic criteria), MCTD initial and follow-up evaluations, MCTD treatment. Early diagnosis, epidemiological data, assessment of burden of disease and QOL aspects are among the unmet needs identified by patients.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Benjamin, ChaigneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Alberto, Scire CarloUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rosaria, TalaricoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tobias, AlexanderUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Zahir, AmouraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tadej, AvcinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lorenzo, BerettaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Andrea, DoriaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Aurelien, GuffroyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vera, GuimaraesUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Eric, HachullaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Thomas, KriegUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
David, LaunayUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gemma, LepriUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pia, MoinzadehUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ulf, Mueller-LadnerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Simona, RednicUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ana, RodriguesUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sander, Tas W.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Van Vollenhoven, R. F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ana, VieiraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stefano, BombardieriUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Eurico, Fonseca JoaoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ilaria, GalettiUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Matthias, SchneiderUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vanessa, SmithUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Maurizio, CutoloUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Marta, MoscaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rebecca, Fischer-BetzUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-169928
DOI: 10.1136/rmdopen-2018-000783
Journal or Publication Title: RMD Open
Volume: 4
Date: 2018
Publisher: BMJ PUBLISHING GROUP
Place of Publication: LONDON
ISSN: 2056-5933
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
AGREE II; RECOMMENDATIONS; ANTIBODYMultiple languages
RheumatologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/16992

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