Emons, Guenter, Steiner, Eric, Vordermark, Dirk, Uleer, Christoph, Bock, Nina, Paradiess, Kerstin, Ortmann, Olaf, Aretz, Stefan ORCID: 0000-0002-5228-1890, Mallmann, Peter, Kurzeder, Christian, Hagen, Volker, van Oorschot, Birgitt, Hoecht, Stefan, Feyer, Petra, Egerer, Gerlinde, Friedrich, Michael, Cremer, Wolfgang, Prott, Franz-Josef, Horn, Lars-Christian, Proempeler, Heinrich, Langrehr, Jan, Leinung, Steffen, Beckmann, Matthias W., Kimmig, Rainer, Letsch, Anne, Reinhardt, Michael, Alt-Epping, Bernd, Kiesel, Ludwig, Menke, Jan, Gebhardt, Marion, Steinke-Lange, Verena, Rahner, Nils, Lichtenegger, Werner, Zeimet, Alain, Hanf, Volker, Weis, Joachim, Mueller, Michael, Henscher, Ulla, Schmutzler, Rita K., Meindl, Alfons, Hilpert, Felix, Panke, Joan Elisabeth, Strnad, Vratislav, Niehues, Christiane, Dauelsberg, Timm, Niehoff, Peter, Mayr, Doris, Grab, Dieter, Kreissl, Michael, Witteler, Ralf, Schorsch, Annemarie, Mustea, Alexander, Petru, Edgar, Huebner, Jutta, Rose, Anne Derke, Wight, Edward, Tholen, Reina, Bauerschmitz, Gerd J., Fleisch, Markus, Juhasz-Boess, Ingolf, Sigurd, Lax, Runnebaum, Ingo, Tempfer, Clemens ORCID: 0000-0002-6904-3258, Nothacker, Monika J., Bloedt, Susanne, Follmann, Markus ORCID: 0000-0003-3790-5578, Langer, Thomas, Raatz, Heike, Wesselmann, Simone and Erdogan, Saskia (2018). Interdisciplinary Diagnosis, Therapy and Follow-up of Patients with Endometrial Cancer. Guideline (S3-Level, AWMF Registry Nummer 032/034-OL, April 2018) - Part 1 with Recommendations on the Epidemiology, Screening, Diagnosis and Hereditary Factors of Endometrial Cancer. Geburtshilfe Frauenheilkd., 78 (10). S. 949 - 971. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1438-8804

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Abstract

The first German interdisciplinary S3-guideline on the diagnosis, therapy and follow-up of patients with endometrial cancer was published in April 2018. Funded by German Cancer Aid as part of an Oncology Guidelines Program, the lead coordinators of the guideline were the German Society of Gynecology and Obstetrics (DGGG) and the Gynecological Oncology Working Group (AGO) of the German Cancer Society (DKG). Purpose The use of evidence-based, risk-adapted therapy to treat low-risk women with endometrial cancer avoids unnecessarily radical surgery and non-useful adjuvant radiotherapy and/or chemotherapy. This can significantly reduce therapy-induced morbidity and improve the patient's quality of life as well as avoiding unnecessary costs. For women with endometrial cancer and a high risk of recurrence, the guideline defines the optimal surgical radicality together with the appropriate chemotherapy and/or adjuvant radiotherapy where required. The evidence-based optimal use of different therapeutic modalities should improve survival rates and the quality of life of these patients. The S3-guideline on endometrial cancer is intended as a basis for certified gynecological cancer centers. The aim is that the quality indicators established in this guideline will be incorporated in the certification processes of these centers. Methods The guideline was compiled in accordance with the requirements for S3-level guidelines. This includes, in the first instance, the adaptation of source guidelines selected using the DELBI instrument for appraising guidelines. Other consulted sources include reviews of evidence which were compiled from literature selected during systematic searches of literature databases using the PICO scheme. In addition, an external biostatistics institute was commissioned to carry out a systematic search and assessment of the literature for one area of the guideline. The identified materials were used by the interdisciplinary working groups to develop suggestions for Recommendations and Statements, which were then modified during structured consensus conferences and/or additionally amended online using the DELPHI method with consent being reached online. The guideline report is freely available online. Recommendations Part 1 of this short version of the guideline presents recommendations on epidemiology, screening, diagnosis and hereditary factors, The epidemiology of endometrial cancer and the risk factors for developing endomentrial cancer are presented. The options for screening and the methods used to diagnose endometrial cancer including the pathology of the cancer are outlined. Recommendations are given for the prevention, diagnosis, and therapy of hereditary forms of endometrial cancer.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Emons, GuenterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Steiner, EricUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vordermark, DirkUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Uleer, ChristophUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bock, NinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Paradiess, KerstinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ortmann, OlafUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Aretz, StefanUNSPECIFIEDorcid.org/0000-0002-5228-1890UNSPECIFIED
Mallmann, PeterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kurzeder, ChristianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hagen, VolkerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
van Oorschot, BirgittUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hoecht, StefanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Feyer, PetraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Egerer, GerlindeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Friedrich, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cremer, WolfgangUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Prott, Franz-JosefUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Horn, Lars-ChristianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Proempeler, HeinrichUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Langrehr, JanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Leinung, SteffenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Beckmann, Matthias W.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kimmig, RainerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Letsch, AnneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Reinhardt, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Alt-Epping, BerndUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kiesel, LudwigUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Menke, JanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gebhardt, MarionUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Steinke-Lange, VerenaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rahner, NilsUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lichtenegger, WernerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Zeimet, AlainUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hanf, VolkerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Weis, JoachimUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mueller, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Henscher, UllaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schmutzler, Rita K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Meindl, AlfonsUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hilpert, FelixUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Panke, Joan ElisabethUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Strnad, VratislavUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Niehues, ChristianeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dauelsberg, TimmUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Niehoff, PeterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mayr, DorisUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Grab, DieterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kreissl, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Witteler, RalfUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schorsch, AnnemarieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mustea, AlexanderUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Petru, EdgarUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Huebner, JuttaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rose, Anne DerkeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wight, EdwardUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tholen, ReinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bauerschmitz, Gerd J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fleisch, MarkusUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Juhasz-Boess, IngolfUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sigurd, LaxUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Runnebaum, IngoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tempfer, ClemensUNSPECIFIEDorcid.org/0000-0002-6904-3258UNSPECIFIED
Nothacker, Monika J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bloedt, SusanneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Follmann, MarkusUNSPECIFIEDorcid.org/0000-0003-3790-5578UNSPECIFIED
Langer, ThomasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Raatz, HeikeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wesselmann, SimoneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Erdogan, SaskiaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-171078
DOI: 10.1055/a-0713-1218
Journal or Publication Title: Geburtshilfe Frauenheilkd.
Volume: 78
Number: 10
Page Range: S. 949 - 971
Date: 2018
Publisher: GEORG THIEME VERLAG KG
Place of Publication: STUTTGART
ISSN: 1438-8804
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
POLYCYSTIC-OVARY-SYNDROME; HORMONE-REPLACEMENT THERAPY; PREEXISTING DIABETES-MELLITUS; BODY-MASS INDEX; LYNCH-SYNDROME; BREAST-CANCER; POSTMENOPAUSAL WOMEN; PHYSICAL-ACTIVITY; GLYCEMIC INDEX; META-ANALYSISMultiple languages
Obstetrics & GynecologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/17107

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