Universität zu Köln

Mylonas, S. N. and Brunkwall, J. S. (2018). What have we learned about aortic aneurysms from prospective randomized trials? Which questions are still open?\. Gefasschirurgie, 23 (5). S. 331 - 340. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1434-3932

Full text not available from this repository.

Abstract

Abdominal aortic aneurysms (AAA) are complex diseases and the management has significantly changed over the last 50 years. With the evolution of surgical techniques, anesthetic procedures and perioperative monitoring, the mortality has nowadays considerably declined. After initiation of the endovascular techniques this method greatly expanded over the next decades and has now become a mainstay in the treatment of AAA. This evolution in the management of AAA is accompanied by a significant increase in the quantity of scientific literature concerning this entity. A handful of randomized controlled trials (RCTs) were conducted in order to clarify the various aspects of the management of AAA. In particular, four RCTs tried to investigate the role of screening for AAA in the general population, whereas four further RCTs tried to identify the optimal treatment modality for small AAA. Great interest has also been raised with respect to the management of asymptomatic AAA > 5.5aEuro<overline>cm, since five RCTs were performed. Finally, three RCTs investigated the potential benefit of the endovascular method on the management of patients with ruptured AAA; however, RCTs are major undertakings and cannot answer all of the questions arising about new technologies. Furthermore, many clinical situations of patients with AAAs have not been the subject of RCTs, although patient care needs to be delivered and decisions have to be made in these situations. The data and conclusions of these RCTs on the management of AAA as well as some of the unanswered questions are reviewed and discussed in this article.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Mylonas, S. N. UNSPECIFIED UNSPECIFIED UNSPECIFIED Brunkwall, J. S. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-175367
DOI:	10.1007/s00772-018-0423-7
Journal or Publication Title:	Gefasschirurgie
Volume:	23
Number:	5
Page Range:	S. 331 - 340
Date:	2018
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1434-3932
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language Peripheral Vascular Disease Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/17536