Universität zu Köln

Halbach, M. and Baldus, S. (2018). Platelet inhibition in patients with coronary, cerebral and peripheral macroangiopathy. What, when and how long? Internist, 59 (3). S. 288 - 304. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-1289

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Abstract

Inhibition of platelet aggregation can reduce the rate of vascular events in patients with coronary artery disease, carotid artery stenosis and symptomatic peripheral arterial disease. The choice of platelet inhibitors in monotherapy and combination therapy as well as the duration of dual platelet inhibition depend on the clinical situation and individual patient characteristics. The present review summarizes the latest data from clinical trials and recommendations regarding platelet inhibition in coronary, cerebral and peripheral arterial disease. A large number of randomized trials on platelet inhibition in different clinical situations have been performed, allowing evidence-based recommendations on the choice of drugs and duration of treatment. Moreover, new guidelines of European professional societies on platelet inhibition in patients with coronary, cerebral and peripheral arterial disease have been recently published. Based on latest randomized trials and major society guidelines, a number of recommendations on platelet inhibition in stable coronary artery disease, after stent implantation, after acute coronary syndromes and in cerebral and peripheral arterial disease can be made.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Halbach, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Baldus, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-193441
DOI:	10.1007/s00108-017-0362-5
Journal or Publication Title:	Internist
Volume:	59
Number:	3
Page Range:	S. 288 - 304
Date:	2018
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1432-1289
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ELEVATION MYOCARDIAL-INFARCTION; DUAL ANTIPLATELET THERAPY; ATRIAL-FIBRILLATION; CARDIOVASCULAR EVENTS; COLLABORATIVE METAANALYSIS; RANDOMIZED-TRIAL; DOUBLE-BLIND; OPEN-LABEL; CLOPIDOGREL; ASPIRIN Multiple languages Medicine, General & Internal Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/19344