Universität zu Köln

Frisch, Barbara K., Slebocki, Karin, Mammadov, Kamal ORCID: 0000-0003-2178-4898, Puesken, Michael, Becker, Ingrid ORCID: 0000-0001-5829-3553, Maintz, David and Chang, De-Hua (2017). Implementation of ultra-low-dose lung protocols in CT-guided lung biopsies: feasibility and safety in the clinical setting. J. Int. Med. Res., 45 (6). S. 2101 - 2110. LONDON: SAGE PUBLICATIONS LTD. ISSN 1473-2300

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Abstract

Objective: To evaluate the use of ultra-low-dose computed tomography (ULDCT) for CT-guided lung biopsy versus standard-dose CT (SDCT). Methods: CT-guided lung biopsies from 115 patients (50 ULDCT, 65 SDCT) were analyzed retrospectively. SDCT settings were 120 kVp with automatic mAs modulation. ULDCT settings were 80 kVp with fixed exposure (20 mAs). Two radiologists evaluated image quality (i.e., needle artifacts, lesion contouring, vessel recognition, visibility of interlobar fissures). Complications and histological results were also evaluated. Results: ULDCT was considered feasible for all lung interventions, showing the same diagnostic accuracy as SDCT. Its mean total radiation dose (dose-length product) was significantly reduced to 34 mGy-cm (SDCT 426 mGy-cm). Image quality and complication rates (P = 0.469) were consistent. Conclusions: ULDCT for CT-guided lung biopsies appears safe and accurate, with a significantly reduced radiation dose. We therefore recommend routine clinical use of ULDCT for the benefit of patients and interventionalists.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Frisch, Barbara K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Slebocki, Karin UNSPECIFIED UNSPECIFIED UNSPECIFIED Mammadov, Kamal UNSPECIFIED orcid.org/0000-0003-2178-4898 UNSPECIFIED Puesken, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Becker, Ingrid UNSPECIFIED orcid.org/0000-0001-5829-3553 UNSPECIFIED Maintz, David UNSPECIFIED UNSPECIFIED UNSPECIFIED Chang, De-Hua UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-208628
DOI:	10.1177/0300060517712165
Journal or Publication Title:	J. Int. Med. Res.
Volume:	45
Number:	6
Page Range:	S. 2101 - 2110
Date:	2017
Publisher:	SAGE PUBLICATIONS LTD
Place of Publication:	LONDON
ISSN:	1473-2300
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ITERATIVE RECONSTRUCTION TECHNIQUE; IMAGE-QUALITY; REDUCTION Multiple languages Medicine, Research & Experimental; Pharmacology & Pharmacy Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/20862