Haidl, Friederike, Pfister, David, Heidenreich, Axel and Heidegger, Isabel (2017). Antiangiogenic therapies in urogenital malignancies. Memo-Mag. Eur. Med. Oncol., 10 (4). S. 202 - 206. WIEN: SPRINGER WIEN. ISSN 1865-5076

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Abstract

The use of antiangiogenic agents in cancer therapy has become an attractive target in oncological research. However, concerning the uro-oncological field, current guidelines only recommend the use of antiangiogenic agents in metastatic renal cell cancer. Yet in recent years, several approaches for sequential treatment with angiogenesis inhibitors in other urogenital malignancies apart from renal cell cancer are ongoing. Thus, the present review article aims to provide an overview about clinical studies with antiangiogenic agents in prostate-, bladder-, testicular-, as well as penile cancer patients. For this, a literature search was conducted using Medline; moreover we performed a systematic review of data presented at this year's important urooncological meetings. Preliminary data revealed that there are several promising studies ongoing in prostate-, bladder-, testicular-, as well as penile cancer; however, larger studies should be conducted to optimize the use of antiangiogenic agents in clinical practice.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Haidl, FriederikeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pfister, DavidUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Heidenreich, AxelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Heidegger, IsabelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-209182
DOI: 10.1007/s12254-017-0375-8
Journal or Publication Title: Memo-Mag. Eur. Med. Oncol.
Volume: 10
Number: 4
Page Range: S. 202 - 206
Date: 2017
Publisher: SPRINGER WIEN
Place of Publication: WIEN
ISSN: 1865-5076
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
ENDOTHELIAL GROWTH-FACTOR; REFRACTORY PROSTATE-CANCER; GERM-CELL TUMORS; SINGLE-ARM; OPEN-LABEL; DOUBLE-BLIND; PREDNISONE; DOCETAXEL; PLACEBO; MENMultiple languages
OncologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/20918

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