Universität zu Köln

D'Souza, Roshan, Pinto, Naina Adren, Higgins, Paul G. ORCID: 0000-0001-8677-9454, Hwang, Insik, Yong, Dongeun, Choi, Jongrak, Lee, Kyoungwon and Chong, Yunsop (2017). First Report of the Carbapenemase Gene bla(OXA-499) in Acinetobacter pittii. Antimicrob. Agents Chemother., 61 (5). WASHINGTON: AMER SOC MICROBIOLOGY. ISSN 1098-6596

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Abstract

We identified the carbapenemase gene bla(OXA-499), a variant of bla(OXA-143), from a clinical isolate of Acinetobacter pittii for the first time. OXA-499 shared 93.1% amino acid identity with OXA-143, and the gene was located on the chromosome. By cloning the OXA-499-encoding gene into the pWH1266 vector and transforming it into susceptible Acinetobacter spp., we were able to show that OXA-499 confers resistance to carbapenems.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code D'Souza, Roshan UNSPECIFIED UNSPECIFIED UNSPECIFIED Pinto, Naina Adren UNSPECIFIED UNSPECIFIED UNSPECIFIED Higgins, Paul G. UNSPECIFIED orcid.org/0000-0001-8677-9454 UNSPECIFIED Hwang, Insik UNSPECIFIED UNSPECIFIED UNSPECIFIED Yong, Dongeun UNSPECIFIED UNSPECIFIED UNSPECIFIED Choi, Jongrak UNSPECIFIED UNSPECIFIED UNSPECIFIED Lee, Kyoungwon UNSPECIFIED UNSPECIFIED UNSPECIFIED Chong, Yunsop UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-233074
DOI:	10.1128/AAC.02676-16
Journal or Publication Title:	Antimicrob. Agents Chemother.
Volume:	61
Number:	5
Date:	2017
Publisher:	AMER SOC MICROBIOLOGY
Place of Publication:	WASHINGTON
ISSN:	1098-6596
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language BETA-LACTAMASES; BAUMANNII; NOSOCOMIALIS; RESISTANCE; OXA-51 Multiple languages Microbiology; Pharmacology & Pharmacy Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/23307