Universität zu Köln

Brunnberg, Uta, Hentrich, Marcus, Hoffmann, Christian, Wolf, Timo and Huebel, Kai (2017). HIV-Associated Malignant Lymphoma. Oncol. Res. Treat., 40 (3). S. 82 - 88. BASEL: KARGER. ISSN 2296-5262

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Abstract

Acquired immune deficiency syndrome (AIDS)-related lymphomas (ARL) still represent a relevant field of clinical research. For Most histological subtypes of ARL, no optimal initial therapy has been clearly defined so far. Rituximab plus chemotherapy is feasible and effective and should be offered to all patients with CD20-positive ARL regardless of their CD4 cell count. Combination antiretroviral therapy (cART) should be given concomitantly with chemotherapy, bearing in mind potential drug-drug interactions. ApprOpriate treatment of ARL is determined by a number of factors such as lymphoma stage, performance status, comorbidities, histological subtype, and immunosuppression. Treatment should principally be the same as in human immunodeficiency virus (HIV)-negative lymphoma patients. In HIV-related Hodgkin's lymphoma, high cure rates have been achieved with stage-adapted treatment approaches, albeit with worse outcomes compared to immunocorinpetent patients. (C) 2017 S. Karger GmbH, Freiburg

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Brunnberg, Uta UNSPECIFIED UNSPECIFIED UNSPECIFIED Hentrich, Marcus UNSPECIFIED UNSPECIFIED UNSPECIFIED Hoffmann, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Wolf, Timo UNSPECIFIED UNSPECIFIED UNSPECIFIED Huebel, Kai UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-238291
DOI:	10.1159/000456036
Journal or Publication Title:	Oncol. Res. Treat.
Volume:	40
Number:	3
Page Range:	S. 82 - 88
Date:	2017
Publisher:	KARGER
Place of Publication:	BASEL
ISSN:	2296-5262
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language HUMAN-IMMUNODEFICIENCY-VIRUS; HEMATOPOIETIC-CELL TRANSPLANTATION; PRIMARY EFFUSION LYMPHOMA; NON-HODGKIN-LYMPHOMA; ACTIVE ANTIRETROVIRAL THERAPY; NERVOUS-SYSTEM LYMPHOMA; INFECTED PATIENTS; PLASMABLASTIC LYMPHOMA; INTENSIVE CHEMOTHERAPY; PROTEASE INHIBITORS Multiple languages Oncology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/23829