Universität zu Köln

Koch, Konrad R., Hishmi, Ahmed M., Ortmann, Monika and Heindl, Ludwig M. (2017). Uveal Melanoma Cell Seeding after Transretinal Tumor Biopsy? Ocul. Oncol. Pathol., 3 (3). S. 164 - 168. BASEL: KARGER. ISSN 2296-4657

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Abstract

Background/Aims: To report a case and the histopathology of uveal melanoma cell seeding following transretinal tumor biopsy for a suspected uveal lesion. Methods: Interventional case report. Results: A 66-year-old male presented with a pigmented perilimbal episcleral lesion overlying an intraocular mass at the pars plana, 3.5 years after transretinal biopsy and ruthenium plaque brachytherapy for a choroidal melanoma at the posterior pole. The patient underwent enucleation of the eye. Histopathology confirmed a recurrence of uveal melanoma with intra-and extrascleral tumor portions. Serial sections revealed the posterior border of this newfound pars plana melanoma separated from the radiation scar by a viable and tumor-free choroidal area, thus failing to establish a continuity between secondary and primary tumor. Conclusion: Transretinal tumor biopsy is of high diagnostic and prognostic value in the management of uveal lesions, but also bears the potential risk for tumor cell seeding. (C) 2017 S. Karger AG, Basel

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Koch, Konrad R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hishmi, Ahmed M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Ortmann, Monika UNSPECIFIED UNSPECIFIED UNSPECIFIED Heindl, Ludwig M. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-245590
DOI:	10.1159/000453360
Journal or Publication Title:	Ocul. Oncol. Pathol.
Volume:	3
Number:	3
Page Range:	S. 164 - 168
Date:	2017
Publisher:	KARGER
Place of Publication:	BASEL
ISSN:	2296-4657
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language FINE-NEEDLE-ASPIRATION; VITRECTOMY Multiple languages Ophthalmology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/24559