Universität zu Köln

Schaub, F., Enders, P. and Fauser, S. (2016). Proliferative Vitreoretinopathy: Therapeutic Strategies. Klinische Monatsblat. Augenheilkunde, 233 (9). S. 1016 - 1024. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1439-3999

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Abstract

Background: Development of proliferative vitreoretinopathy (PVR) is one of the most important complications of vitreoretinal surgery. Reaching the decision to treat and surgical treatment itself are both challenging. Materials and Methods: Our own data and a review of the literature in PubMed are summarised. Results: Pharmacological approaches to the prevention and treatment of proliferative vitreoretinopathy have been limited to concepts that have been investigated in preclinical and a few clinical studies. Anti-inflammatory and antiproliferative substances may be mentioned in this context. Surgical techniques range from scleral buckling to the gold standard pars plana vitrectomy, preferably with silicone oil endotamponade. Applying an encircling band, retinotomy or retinectomy can be useful in reattaching the tractional shortened retina. Conclusion: Surgery is still the method of choice for the treatment of PVR. Pharmacological strategies to prevent or treat PVR have not been established.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schaub, F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Enders, P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Fauser, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-264161
DOI:	10.1055/s-0042-107947
Journal or Publication Title:	Klinische Monatsblat. Augenheilkunde
Volume:	233
Number:	9
Page Range:	S. 1016 - 1024
Date:	2016
Publisher:	GEORG THIEME VERLAG KG
Place of Publication:	STUTTGART
ISSN:	1439-3999
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language RHEGMATOGENOUS RETINAL-DETACHMENT; MOLECULAR-WEIGHT HEPARIN; PARS-PLANA VITRECTOMY; RANDOMIZED CONTROLLED-TRIAL; ORAL 13-CIS-RETINOIC ACID; CONTROLLED CLINICAL-TRIAL; PIGMENT EPITHELIAL-CELLS; SILICONE OIL; 23-GAUGE VITRECTOMY; 25-GAUGE VITRECTOMY Multiple languages Ophthalmology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/26416