Tharun, Lars, Steuer, Stefan and Quaas, Alexander (2016). Role of pathologists with respect to therapy decisions for gastric cancer. Onkologe, 22 (6). S. 400 - 406. NEW YORK: SPRINGER. ISSN 1433-0415

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Abstract

The role of pathologists in gastric cancer management is expanding to tumor subtyping analogous to recent genetic findings and the detection of biomarkers to reveal additional therapeutic options. The purpose of this article is to provide an overview of the current role of pathologists in gastric cancer and particularly with respect to guiding therapeutic decisions. This article is based on a selective literature review using PubMed database and World Health Organization (WHO) publications in particular on the clinically relevant problems in gastric cancer which pathologists are currently confronted with. New sequencing techniques recently allowed a molecular-based classification of gastric carcinoma. The results underline the overlap between morphologically and molecularly defined subtypes which can provide guidelines for biomarker exploration aimed at disclosing new therapeutic options.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Tharun, LarsUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Steuer, StefanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Quaas, AlexanderUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-273910
DOI: 10.1007/s00761-016-0033-5
Journal or Publication Title: Onkologe
Volume: 22
Number: 6
Page Range: S. 400 - 406
Date: 2016
Publisher: SPRINGER
Place of Publication: NEW YORK
ISSN: 1433-0415
Language: German
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
NEOADJUVANT CHEMOTHERAPY; COLORECTAL-CANCER; TUMOR-REGRESSION; CARCINOMA; ADENOCARCINOMAS; RISKMultiple languages
OncologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/27391

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