Universität zu Köln

Neef, Daniela, Berthold, Heiner K. and Gouni-Berthold, Ioanna (2016). Lomitapide for use in patients with homozygous familial hypercholesterolemia: a narrative review. Expert Rev. Clin. Pharmacol., 9 (5). S. 655 - 664. ABINGDON: TAYLOR & FRANCIS LTD. ISSN 1751-2441

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Abstract

Lomitapide is a drug recently approved for the treatment of patients with homozygous familial hypercholesterolemia. In this article we discuss briefly the pharmacology of this drug followed by a comprehensive narrative review of the available preclinical and clinical data on its safety and efficacy. Only data published as full papers are presented, with the exception of one long-term open-label extension study, which is available only in abstract form.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Neef, Daniela UNSPECIFIED UNSPECIFIED UNSPECIFIED Berthold, Heiner K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Gouni-Berthold, Ioanna UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-276018
DOI:	10.1586/17512433.2016.1162095
Journal or Publication Title:	Expert Rev. Clin. Pharmacol.
Volume:	9
Number:	5
Page Range:	S. 655 - 664
Date:	2016
Publisher:	TAYLOR & FRANCIS LTD
Place of Publication:	ABINGDON
ISSN:	1751-2441
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language TRIGLYCERIDE TRANSFER PROTEIN; DENSITY-LIPOPROTEIN CHOLESTEROL; MTP INHIBITOR; SINGLE-ARM; OPEN-LABEL; MIPOMERSEN; MANAGEMENT; DIAGNOSIS; DISEASE; DRUGS Multiple languages Pharmacology & Pharmacy Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/27601