Moenig, S. P. and Schiffmann, L. M. (2016). Resection of advanced esophagogastric adenocarcinoma. Extended indications. Chirurg, 87 (5). S. 398 - 406. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-0385
Full text not available from this repository.Abstract
In the current German S3 guidelines surgical treatment is not recommended for metastatic gastric cancer or metastatic adenocarcinoma of the esophagogastric junction; however, in routine practice the indications can be extended so that there may be occasions in which radical surgical intervention for specific individuals may be appropriate as part of a multimodal therapy with curative intent. This article presents the scientific rationale of such an approach based on the available literature considering modern, multimodal therapy concepts including criteria to be met for radical surgery. Currently only retrospective trials and limited current meta-analysis data are available for justifying surgical treatment for metastatic adenocarcinoma. The recently published initial results of the FLOT-3 study identified a patient subgroup that benefits from a resection even though metastasis has occurred. Whether surgical therapy will become an integral part of the treatment of limited metastatic adenocarcinoma of the stomach and esophagus in the future, has to be demonstrated by large prospective randomized studies, such as the RENAISSANCE/FLOT-5 study.
Item Type: | Journal Article | ||||||||||||
Creators: |
|
||||||||||||
URN: | urn:nbn:de:hbz:38-276782 | ||||||||||||
DOI: | 10.1007/s00104-016-0183-4 | ||||||||||||
Journal or Publication Title: | Chirurg | ||||||||||||
Volume: | 87 | ||||||||||||
Number: | 5 | ||||||||||||
Page Range: | S. 398 - 406 | ||||||||||||
Date: | 2016 | ||||||||||||
Publisher: | SPRINGER HEIDELBERG | ||||||||||||
Place of Publication: | HEIDELBERG | ||||||||||||
ISSN: | 1433-0385 | ||||||||||||
Language: | German | ||||||||||||
Faculty: | Unspecified | ||||||||||||
Divisions: | Unspecified | ||||||||||||
Subjects: | no entry | ||||||||||||
Uncontrolled Keywords: |
|
||||||||||||
Refereed: | Yes | ||||||||||||
URI: | http://kups.ub.uni-koeln.de/id/eprint/27678 |
Downloads
Downloads per month over past year
Altmetric
Export
Actions (login required)
View Item |