Freitag, Christine M., Jensen, Katrin ORCID: 0000-0002-5088-5279, Elsuni, Leyla, Sachse, Michael, Herpertz-Dahlmann, Beate, Schulte-Ruether, Martin, Haenig, Susann, von Gontard, Alexander, Poustka, Luise, Schad-Hansjosten, Tanja, Wenzl, Christina, Sinzig, Judith, Taurines, Regina, Geissler, Julia ORCID: 0000-0003-1878-9647, Kieser, Meinhard and Cholemkery, Hannah (2016). Group-based cognitive behavioural psychotherapy for children and adolescents with ASD: the randomized, multicentre, controlled SOSTA - net trial. J. Child Psychol. Psychiatry, 57 (5). S. 596 - 606. HOBOKEN: WILEY. ISSN 1469-7610

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Abstract

Background: Group-based psychotherapy in Autism Spectrum Disorder (ASD) has predominantly been studied in the United States by small studies in school-aged children without long-term follow-up. We report results of a large, confirmatory, multicentre randomized-controlled phase-III trial in children and adolescents studying the ASD specific, manualized group-based cognitive behavioural SOSTA-FRA approach. Methods: High-functioning ASD individuals aged 8-19 years old were randomized to 12 sessions SOSTA-FRA or treatment as usual. Primary outcomes were change in total raw score of the parent-rated Social Responsiveness Scale (pSRS) between baseline (T2) and end of intervention (T4), and between T2 and 3 months after end of intervention (T5). Trial registration: ISRCTN94863788. Results: Between 20/5/2010 and 14/2/2013, n = 320 ASD patients were screened, n = 228 patients were randomized, and N = 209 analysed. Mean pSRS difference between groups at T4 was -6.5 (95% CI -11.6 to -1.4; p = .013), and at T5 -6.4 (-11.5 to -1.3, p = .015). Pre-treatment SRS and IQ were positively associated with stronger improvement at T4 and T5. Conclusions: Short-term ASD-specific add-on group-based psychotherapy has shown postintervention efficacy with regard to parent-rated social responsiveness predominantly in male high-functioning children and adolescents with ASD. Future studies should implement blinded standardized observational measures of peer-related social interaction.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Freitag, Christine M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jensen, KatrinUNSPECIFIEDorcid.org/0000-0002-5088-5279UNSPECIFIED
Elsuni, LeylaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sachse, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Herpertz-Dahlmann, BeateUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schulte-Ruether, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Haenig, SusannUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
von Gontard, AlexanderUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Poustka, LuiseUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schad-Hansjosten, TanjaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wenzl, ChristinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sinzig, JudithUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Taurines, ReginaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Geissler, JuliaUNSPECIFIEDorcid.org/0000-0003-1878-9647UNSPECIFIED
Kieser, MeinhardUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cholemkery, HannahUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-277363
DOI: 10.1111/jcpp.12509
Journal or Publication Title: J. Child Psychol. Psychiatry
Volume: 57
Number: 5
Page Range: S. 596 - 606
Date: 2016
Publisher: WILEY
Place of Publication: HOBOKEN
ISSN: 1469-7610
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
HIGH-FUNCTIONING AUTISM; SOCIAL-SKILLS; SPECTRUM DISORDER; DIFFICULTIES QUESTIONNAIRE; EMOTION RECOGNITION; ASPERGER-SYNDROME; YOUNG-CHILDREN; INTERVENTION; POPULATION; ADULTHOODMultiple languages
Psychology, Developmental; Psychiatry; PsychologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/27736

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