Universität zu Köln

Bachmann, B., Schaub, F. and Cursiefen, C. (2016). Treatment of corneal endothelial disorders by DMEK and UT-DSAEK. Indications, complications, results and follow-up. Ophthalmologe, 113 (3). S. 196 - 203. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-0423

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Abstract

Various techniques for posterior lamellar keratoplasty have been established for the clinical routine and continuously improved during the last 15 years so that an extremely rapid recovery of vision is possible due to very thin transplants. Descemet membrane endothelial keratoplasty (DMEK) is the method of choice for simple corneal endothelial diseases and has already been applied in complex conditions of the anterior segment. The learning curve for DMEK is comparatively long and the risk of complications in complex anterior segment pathologies is higher than in Descemet's stripping automated endothelial keratoplasty (DSAEK); however, DMEK results in better visual outcome and less graft rejections than DSAEK. The latest evolution in posterior lamellar transplant surgery is ultrathin DSAEK (UT-DSAEK), where the grafted lamella is much thinner than in conventional DSAEK. Currently available data suggest that the resulting visual acuity after UT-DSAEK is close to the visual acuity seen after DMEK; however, studies comparing the results after DMEK and UT-DSAEK are so far lacking. Whether the transplantation of these very thin DSAEK grafts also results in endothelial cell densities and graft rejection rates comparable to DMEK has to be proven.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Bachmann, B. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schaub, F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Cursiefen, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-282702
DOI:	10.1007/s00347-016-0221-0
Journal or Publication Title:	Ophthalmologe
Volume:	113
Number:	3
Page Range:	S. 196 - 203
Date:	2016
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1433-0423
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PREDNISOLONE ACETATE 1-PERCENT; KERATOPLASTY DSAEK; IMMUNE-REACTIONS; THICKNESS; CHILDREN; SURGERY Multiple languages Ophthalmology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/28270