Universität zu Köln

Abken, Hinrich (2016). Costimulation Engages the Gear in Driving CARs. Immunity, 44 (2). S. 214 - 217. CAMBRIDGE: CELL PRESS. ISSN 1097-4180

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Abstract

In this issue of Immunity, Kawalekar et al. (2016) find that costimulation by a chimeric antigen receptor (CAR) can control T cell metabolism and balance the response toward long-lived memory or short-lived effector cells. The results provide a rationale of how to tune cancer immunotherapy more effectively in a hostile tumor environment.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Abken, Hinrich UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-284468
DOI:	10.1016/j.immuni.2016.02.001
Journal or Publication Title:	Immunity
Volume:	44
Number:	2
Page Range:	S. 214 - 217
Date:	2016
Publisher:	CELL PRESS
Place of Publication:	CAMBRIDGE
ISSN:	1097-4180
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CHIMERIC ANTIGEN RECEPTORS; REDIRECTED T-CELLS; EFFICACY Multiple languages Immunology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/28446