Robotic-assisted radiosurgery for the treatment of vasoproliferative tumours

Schmelter, Valerie, Fuerweger, Christoph, Muacevic, Alexander, Priglinger, Siegfried G., Foerster, Paul and Liegl, Raffael . Robotic-assisted radiosurgery for the treatment of vasoproliferative tumours. Acta Ophthalmol.. HOBOKEN: WILEY. ISSN 1755-3768

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DOI:10.1111/aos.14609

Abstract

Purpose Vasoproliferative tumours (VPT) are a rare but benign entity that can lead to severe visual acuity deterioration. There is no standard of care, and depending on the degree of clinical features, including tumour size and dissemination, visual acuity and subretinal fluid, treatment options include observation, cryotherapy and brachytherapy. Particularly in larger tumours, brachytherapy has advantages over other options, although higher radiation doses and the need for surgical application are disadvantages of this otherwise effective treatment option. CyberKnife radiosurgery might represent an alternative therapeutic option as no surgical intervention is needed and radiation doses are lower. Methods All patients diagnosed with vasoproliferative tumors who were treated with CyberKnife radiosurgery with a minimum follow-up time of 12 months were included in this case series. We recorded visual acuity, number of lesions, central retinal thickness with optical coherence tomography (OCT) and reflectivity using A-scan standardizes echography every three months. Results A total of four patients with a median age of 34 years (range: 24 - 51) who were observed over an average of 26.5 months (range: 17 - 49 months) matched our inclusion criteria. We appreciated stabilization or increase in visual acuity in all four patients and a regression in tumour thickness with subsequent increase in internal reflectivity as a marker of increasing fibrosis. Conclusion We observed good visual and functional outcome following CyberKnife therapy for VPT. We believe that further studies should be pursued to evaluate CyberKnife therapy for the treatment of VPT not treatable with cryo- or lasertherapy.

Item Type:

Journal Article

Creators:

Creators	Email	ORCID	ORCID Put Code
Schmelter, Valerie	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Fuerweger, Christoph	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Muacevic, Alexander	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Priglinger, Siegfried G.	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Foerster, Paul	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED
Liegl, Raffael	UNSPECIFIED	UNSPECIFIED	UNSPECIFIED