Universität zu Köln

Hayashi, Takahiko ORCID: 0000-0001-8704-680X, Yasutsugu, Ida, Shimizu, Toshiki, Kuroki, Tsubasa, Kobashigawa, Yuji, Iijima, Yasuhito and Yuda, Kentaro (2020). Pars plana vitrectomy combined with penetrating keratoplasty and transscleral-sutured intraocular lens implantation in complex eyes: a case series. BMC Ophthalmol., 20 (1). LONDON: BMC. ISSN 1471-2415

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Abstract

Background The aim of this study was to evaluate the clinical outcomes of pars plana vitrectomy (PPV) combined with penetrating keratoplasty (PKP) and transscleral-sutured intraocular lens (IOL) implantation (IOL-suture) in complex eyes. Methods In this prospective, consecutive interventional case series, patients who underwent PKP combined with PPV and IOL implantation from July 2014 to March 2018 at Yokohama Minami Kyosai Hospital were enrolled. The postoperative best corrected visual acuity (BCVA) (converted to logarithm of the minimal angle of resolution [logMAR] units), intraocular pressure (IOP, mmHg), endothelial cell density (ECD, cells/mm(2)), graft survival, complications, astigmatism, and spherical equivalent (dioptres [D]) were evaluated. Results This study included 11 eyes of 11 patients (three females and eight males; mean age, 61.8 +/- 13.9 years) with an injury (n = 6) or bullous keratopathy (n = 5). The BCVA significantly improved from 1.50 +/- 0.66 logMAR preoperatively to 0.78 +/- 0.59 logMAR (p < 0.001) postoperatively. The baseline ECD significantly decreased from 2396 +/- 238 cells/mm(2)preoperatively to 1132 +/- 323 cells/mm(2)(p < 0.001) postoperatively. Despite two rejection episodes, graft survival rates were 100%. The mean follow-up period was 38.0 +/- 20.5 months. Two patients required combined glaucoma surgery, and three patients underwent subsequent glaucoma surgery. Postoperative astigmatism and spherical equivalent were 3.9 +/- 3.2 D and 0.29 +/- 2.18 D, respectively. Conclusion The combination of PKP, PPV, and IOL-suture implantation could be a safe and effective approach for eyes requiring anterior segment surgery; however, these eyes are associated with a higher incidence of glaucoma surgery.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Hayashi, Takahiko UNSPECIFIED orcid.org/0000-0001-8704-680X UNSPECIFIED Yasutsugu, Ida UNSPECIFIED UNSPECIFIED UNSPECIFIED Shimizu, Toshiki UNSPECIFIED UNSPECIFIED UNSPECIFIED Kuroki, Tsubasa UNSPECIFIED UNSPECIFIED UNSPECIFIED Kobashigawa, Yuji UNSPECIFIED UNSPECIFIED UNSPECIFIED Iijima, Yasuhito UNSPECIFIED UNSPECIFIED UNSPECIFIED Yuda, Kentaro UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-319180
DOI:	10.1186/s12886-020-01639-y
Journal or Publication Title:	BMC Ophthalmol.
Volume:	20
Number:	1
Date:	2020
Publisher:	BMC
Place of Publication:	LONDON
ISSN:	1471-2415
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language AHMED GLAUCOMA VALVE; CORNEAL GRAFT-SURVIVAL; PRESSURE CONTROL; OUTCOMES; TRANSPLANTATION; REJECTION; FIXATION; LAMELLAR; TRENDS Multiple languages Ophthalmology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/31918