Universität zu Köln

Herkenrath, Simon and Randerath, Winfried (2020). Obesity-related breathing disorders: State of the Art. Somnologie, 24 (3). S. 168 - 176. CHAM: SPRINGER INTERNATIONAL PUBLISHING AG. ISSN 1439-054X

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Abstract

Obesity-related breathing disorders include obstructive sleep apnea, sleep-related alveolar hypoventilation, and full-blown obesity hypoventilation syndrome. The pathophysiology is based on obesity-related changes of the respiratory system, with upper-airway collapsibility, reduced thoracic compliance, increased intrinsic positive end-expiratory pressure, increased ventilation-perfusion mismatch, and reduced carbon dioxide sensitivity. There is a close correlation with metabolic and cardiovascular diseases such as heart failure, coronary heart disease, and pulmonary hypertension. Depending on the pathophysiological accentuation, continuous and bilevel positive pressure are established therapy-methods.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Herkenrath, Simon UNSPECIFIED UNSPECIFIED UNSPECIFIED Randerath, Winfried UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-323324
DOI:	10.1007/s11818-020-00258-5
Journal or Publication Title:	Somnologie
Volume:	24
Number:	3
Page Range:	S. 168 - 176
Date:	2020
Publisher:	SPRINGER INTERNATIONAL PUBLISHING AG
Place of Publication:	CHAM
ISSN:	1439-054X
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language OBSTRUCTIVE SLEEP-APNEA; POSITIVE-PRESSURE VENTILATION; CHRONIC RESPIRATORY-FAILURE; HYPOVENTILATION SYNDROME; NONINVASIVE VENTILATION; CLINICAL CHARACTERISTICS; MECHANICAL VENTILATION; WEIGHT-LOSS; HYPERCAPNIA; CPAP Multiple languages Clinical Neurology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/32332