Universität zu Köln

Zander, Thomas and Moehler, Markus (2020). Multimodal therapy of gastric cancer. Onkologe, 26 (10). S. 912 - 918. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1433-0415

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Abstract

Background Gastric cancer often presents in a locally advanced stage which cannot be cured by endoscopic resection. In November 2019, the new German S3 guideline for the diagnosis and treatment of adenocarcinoma of the stomach and gastroesophageal junction was published. Aim The goal of this work is to summarize the current standard of therapy for adenocarcinoma of the stomach. Materials and methods A literature search with a focus on locally advanced tumors was performed and compared to the current guideline. Results In the new German S3 guideline published in autumn 2019, multimodal therapy for locally advanced gastric cancer was underlined, as it leads to a cure rate of nearly 50%. The FLOT regimen which includes 5-fluorouracil (5-FU), oxaliplatin, docetaxel (e.g., Taxotere (R)) has been clearly established as the European standard for perioperative chemotherapy. However, further optimization of the treatment within the framework of clinical trials is necessary. Conclusion For patients with locally advanced gastric cancer, multimodal therapy is standard.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Zander, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Moehler, Markus UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-323906
DOI:	10.1007/s00761-020-00805-7
Journal or Publication Title:	Onkologe
Volume:	26
Number:	10
Page Range:	S. 912 - 918
Date:	2020
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1433-0415
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PERIOPERATIVE CHEMOTHERAPY; SURGERY; ADENOCARCINOMA Multiple languages Oncology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/32390