Universität zu Köln

Westphalen, Benedikt C., Bokemeyer, Carsten, Buettner, Reinhard, Froehling, Stefan, Gaidzik, Verena I., Glimm, Hanno, Hacker, Ulrich T., Heinemann, Volker, Illert, Anna L., Keilholz, Ulrich, Kindler, Thomas, Kirschner, Martin, Schilling, Bastian ORCID: 0000-0001-8859-4103, Siveke, Jens T., Schroeder, Thomas, Tischler, Verena ORCID: 0000-0002-6673-8329, Wagner, Sebastian, Weichert, Wilko, Zips, Daniel and Loges, Sonja (2020). Conceptual framework for precision cancer medicine in Germany: Consensus statement of the Deutsche Krebshilfe working group 'Molecular Diagnostics and Therapy'. Eur. J. Cancer, 135. S. 1 - 8. OXFORD: ELSEVIER SCI LTD. ISSN 1879-0852

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Abstract

Precision cancer medicine (PCM) holds great promises to offer more effective therapies to patients based on molecular profiling of their individual tumours. Although the PCM approach seems intuitive, multiple conceptional and structural challenges interfere with the broad implementation of PCM into clinical practice. Accordingly, concerted national and international efforts are needed to guide the further development and broad adoption of PCM in Germany. With support of the 'German Cancer Aid' (Deutsche Krebshilfe [DKH]) a task force 'Molecular Diagnostics and Therapy' was implemented. In two workshops supported by the DKH, delegates from the fourteen comprehensive cancer centresidentified key topics essential to implement quality-guided, harmonized and adaptable PCM. Based on an online questionnaire and using a modified Delphi approach, nine statements were drafted and evaluated within the group. These statements could serve as a basis to define a collaborative strategy for PCM in the future with the aim to sustain and further improve its quality. (C) 2020 Elsevier Ltd. All rights reserved.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Westphalen, Benedikt C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Bokemeyer, Carsten UNSPECIFIED UNSPECIFIED UNSPECIFIED Buettner, Reinhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Froehling, Stefan UNSPECIFIED UNSPECIFIED UNSPECIFIED Gaidzik, Verena I. UNSPECIFIED UNSPECIFIED UNSPECIFIED Glimm, Hanno UNSPECIFIED UNSPECIFIED UNSPECIFIED Hacker, Ulrich T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Heinemann, Volker UNSPECIFIED UNSPECIFIED UNSPECIFIED Illert, Anna L. UNSPECIFIED UNSPECIFIED UNSPECIFIED Keilholz, Ulrich UNSPECIFIED UNSPECIFIED UNSPECIFIED Kindler, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Kirschner, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Schilling, Bastian UNSPECIFIED orcid.org/0000-0001-8859-4103 UNSPECIFIED Siveke, Jens T. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schroeder, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED Tischler, Verena UNSPECIFIED orcid.org/0000-0002-6673-8329 UNSPECIFIED Wagner, Sebastian UNSPECIFIED UNSPECIFIED UNSPECIFIED Weichert, Wilko UNSPECIFIED UNSPECIFIED UNSPECIFIED Zips, Daniel UNSPECIFIED UNSPECIFIED UNSPECIFIED Loges, Sonja UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-325299
DOI:	10.1016/j.ejca.2020.04.019
Journal or Publication Title:	Eur. J. Cancer
Volume:	135
Page Range:	S. 1 - 8
Date:	2020
Publisher:	ELSEVIER SCI LTD
Place of Publication:	OXFORD
ISSN:	1879-0852
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language REAL-WORLD EVIDENCE; CLINICAL-ONCOLOGY; AMERICAN-SOCIETY; VARIANTS Multiple languages Oncology Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/32529