Universität zu Köln

Werner, Jan-Michael ORCID: 0000-0001-7147-4594, Lohmann, Philipp ORCID: 0000-0002-5360-046X, Fink, Gereon R. ORCID: 0000-0002-8230-1856, Langen, Karl-Josef ORCID: 0000-0003-1101-5075 and Galldiks, Norbert ORCID: 0000-0002-2485-1796 (2020). Current Landscape and Emerging Fields of PET Imaging in Patients with Brain Tumors. Molecules, 25 (6). BASEL: MDPI. ISSN 1420-3049

Full text not available from this repository.

Abstract

The number of positron-emission tomography (PET) tracers used to evaluate patients with brain tumors has increased substantially over the last years. For the management of patients with brain tumors, the most important indications are the delineation of tumor extent (e.g., for planning of resection or radiotherapy), the assessment of treatment response to systemic treatment options such as alkylating chemotherapy, and the differentiation of treatment-related changes (e.g., pseudoprogression or radiation necrosis) from tumor progression. Furthermore, newer PET imaging approaches aim to address the need for noninvasive assessment of tumoral immune cell infiltration and response to immunotherapies (e.g., T-cell imaging). This review summarizes the clinical value of the landscape of tracers that have been used in recent years for the above-mentioned indications and also provides an overview of promising newer tracers for this group of patients.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Werner, Jan-Michael UNSPECIFIED orcid.org/0000-0001-7147-4594 UNSPECIFIED Lohmann, Philipp UNSPECIFIED orcid.org/0000-0002-5360-046X UNSPECIFIED Fink, Gereon R. UNSPECIFIED orcid.org/0000-0002-8230-1856 UNSPECIFIED Langen, Karl-Josef UNSPECIFIED orcid.org/0000-0003-1101-5075 UNSPECIFIED Galldiks, Norbert UNSPECIFIED orcid.org/0000-0002-2485-1796 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-341597
DOI:	10.3390/molecules25061471
Journal or Publication Title:	Molecules
Volume:	25
Number:	6
Date:	2020
Publisher:	MDPI
Place of Publication:	BASEL
ISSN:	1420-3049
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language POSITRON-EMISSION-TOMOGRAPHY; GROWTH-FACTOR RECEPTOR; RECURRENT MALIGNANT GLIOMA; MUTANT IDH1 EXPRESSION; AMINO-ACID PET; PERIPHERAL BENZODIAZEPINE-RECEPTOR; CENTRAL-NERVOUS-SYSTEM; HIGH-GRADE GLIOMA; F-DOPA PET; O-(2-F-18-FLUOROETHYL)-L-TYROSINE PET Multiple languages Biochemistry & Molecular Biology; Chemistry, Multidisciplinary Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/34159