Duchamp, V., Bastisch, I. and Schneider, P. M. (2015). Drop-out model optimization on degraded DNA samples. Forensic Sci. Int. Genet. Suppl. Ser., 5. S. E370 - 3. CLARE: ELSEVIER IRELAND LTD. ISSN 1875-175X
Full text not available from this repository.Abstract
Two statistical models have been developed to interpret locus drop-out resulting from degraded DNA samples. These models are based on an experimental dataset of 600 genotyping experiments. The first model presents the probability of locus drop-out against the average peak height with a lower and upper confidence interval. For a given peak height average, the probability of drop-out can be quite wide. This probability decreases rapidly when the profile quality increases. For the second model, we have fitted the probability of locus drop-out against the number of base pairs with a lower and upper confidence interval. The probability of drop-out is increasing along with the number of base pairs. Despite DNA degradation effects, the drop-out probability does not get higher than 0.5. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
Item Type: | Journal Article | ||||||||||||||||
Creators: |
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URN: | urn:nbn:de:hbz:38-384463 | ||||||||||||||||
DOI: | 10.1016/j.fsigss.2015.09.147 | ||||||||||||||||
Journal or Publication Title: | Forensic Sci. Int. Genet. Suppl. Ser. | ||||||||||||||||
Volume: | 5 | ||||||||||||||||
Page Range: | S. E370 - 3 | ||||||||||||||||
Date: | 2015 | ||||||||||||||||
Publisher: | ELSEVIER IRELAND LTD | ||||||||||||||||
Place of Publication: | CLARE | ||||||||||||||||
ISSN: | 1875-175X | ||||||||||||||||
Language: | English | ||||||||||||||||
Faculty: | Unspecified | ||||||||||||||||
Divisions: | Unspecified | ||||||||||||||||
Subjects: | no entry | ||||||||||||||||
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URI: | http://kups.ub.uni-koeln.de/id/eprint/38446 |
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