Lam, Max, Rashid, Nur Amirah Abdul, Lee, Sara-Ann, Lim, Jeanette, Foussias, George, Fervaha, Gagan, Ruhrman, Stephan, Remington, Gary and Lee, Jimmy ORCID: 0000-0002-7724-7445 (2015). Baseline social amotivation predicts 1-year functioning in UHR subjects: A validation and prospective investigation. Eur. Neuropsychopharmacol., 25 (12). S. 2187 - 2197. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1873-7862
Full text not available from this repository.Abstract
Social amotivation and diminished expression have been reported to underlie negative symptomatology in schizophrenia. In the current study we sought to establish and validate these negative symptom domains in a large cohort of schizophrenia subjects (n=887) and individuals who are deemed to be Ultra-High Risk (UHR) for psychosis. Confirmatory factor analysis conducted on PANSS item domains demonstrate that the dual negative symptom domains exist in schizophrenia and UHR subjects. We further sought to examine if these negative symptom domains were associated with functioning in UHR subjects. Linear regression analyses confirmed that social amotivation predicted functioning in UHR subjects prospectively at 1 year follow up. Results suggest that the association between social amotivation and functioning is generalisable beyond schizophrenia populations to those who are at-risk of developing psychosis. Social amotivation may be an important dimensional clinical construct to be studied across a range of psychiatric conditions. (C) 2015 Elsevier B.V. and ECNR All rights reserved.
Item Type: | Journal Article | ||||||||||||||||||||||||||||||||||||||||
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URN: | urn:nbn:de:hbz:38-385015 | ||||||||||||||||||||||||||||||||||||||||
DOI: | 10.1016/j.euroneuro.2015.10.007 | ||||||||||||||||||||||||||||||||||||||||
Journal or Publication Title: | Eur. Neuropsychopharmacol. | ||||||||||||||||||||||||||||||||||||||||
Volume: | 25 | ||||||||||||||||||||||||||||||||||||||||
Number: | 12 | ||||||||||||||||||||||||||||||||||||||||
Page Range: | S. 2187 - 2197 | ||||||||||||||||||||||||||||||||||||||||
Date: | 2015 | ||||||||||||||||||||||||||||||||||||||||
Publisher: | ELSEVIER SCIENCE BV | ||||||||||||||||||||||||||||||||||||||||
Place of Publication: | AMSTERDAM | ||||||||||||||||||||||||||||||||||||||||
ISSN: | 1873-7862 | ||||||||||||||||||||||||||||||||||||||||
Language: | English | ||||||||||||||||||||||||||||||||||||||||
Faculty: | Unspecified | ||||||||||||||||||||||||||||||||||||||||
Divisions: | Unspecified | ||||||||||||||||||||||||||||||||||||||||
Subjects: | no entry | ||||||||||||||||||||||||||||||||||||||||
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URI: | http://kups.ub.uni-koeln.de/id/eprint/38501 |
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