Universität zu Köln

Hajek, Andre ORCID: 0000-0002-6886-2745, Brettschneider, Christian ORCID: 0000-0002-5280-1075, Ernst, Annette, Lange, Carolin, Wiese, Birgitt, Prokein, Jana, Weyerer, Siegfried, Werle, Jochen, Pentzek, Michael, Fuchs, Angela, Stein, Janine, Bickel, Horst, Moesch, Edelgard, Heser, Kathrin, Jessen, Frank, Maier, Wolfgang, Scherer, Martin, Riedel-Heller, Steffi G. and Konig, Hans-Helmut ORCID: 0000-0001-5711-6862 (2015). Complex coevolution of depression and health-related quality of life in old age. Qual. Life Res., 24 (11). S. 2713 - 2723. DORDRECHT: SPRINGER. ISSN 1573-2649

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Abstract

Purpose To investigate the coevolution of depression and health-related quality of life (HRQoL) in old age. Methods In a representative survey of the German general population aged 75 years and older, the course of HRQoL and depression was observed over 4.5 years (3 waves). HRQoL was assessed by the Visual Analogue Scale (EQ VAS) of the EQ-5D instrument, while the Geriatric Depression Scale was used to measure depression. A panel vector autoregressive model was used to account for the complex coevolution of depression and HRQoL. Unobserved heterogeneity was taken into account by taking the first differences. Results We revealed a robust negative association between an initial change in HRQoL and a subsequent change in depression score, with substantial sex differences: In women there was a robust association, while in men the significance of this association depended on the model specification. Surprisingly, in the total sample and in both sexes, no robust association between an initial increase in depression and a subsequent change in HRQoL was found. Conclusions Findings indicate that the direction of evolution from HRQoL to depression deserves more attention. Furthermore, treatment of depression in late life should aim at improving HRQoL in which remission of depressive symptoms is necessary but not sufficient.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Hajek, Andre UNSPECIFIED orcid.org/0000-0002-6886-2745 UNSPECIFIED Brettschneider, Christian UNSPECIFIED orcid.org/0000-0002-5280-1075 UNSPECIFIED Ernst, Annette UNSPECIFIED UNSPECIFIED UNSPECIFIED Lange, Carolin UNSPECIFIED UNSPECIFIED UNSPECIFIED Wiese, Birgitt UNSPECIFIED UNSPECIFIED UNSPECIFIED Prokein, Jana UNSPECIFIED UNSPECIFIED UNSPECIFIED Weyerer, Siegfried UNSPECIFIED UNSPECIFIED UNSPECIFIED Werle, Jochen UNSPECIFIED UNSPECIFIED UNSPECIFIED Pentzek, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Fuchs, Angela UNSPECIFIED UNSPECIFIED UNSPECIFIED Stein, Janine UNSPECIFIED UNSPECIFIED UNSPECIFIED Bickel, Horst UNSPECIFIED UNSPECIFIED UNSPECIFIED Moesch, Edelgard UNSPECIFIED UNSPECIFIED UNSPECIFIED Heser, Kathrin UNSPECIFIED UNSPECIFIED UNSPECIFIED Jessen, Frank UNSPECIFIED UNSPECIFIED UNSPECIFIED Maier, Wolfgang UNSPECIFIED UNSPECIFIED UNSPECIFIED Scherer, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Riedel-Heller, Steffi G. UNSPECIFIED UNSPECIFIED UNSPECIFIED Konig, Hans-Helmut UNSPECIFIED orcid.org/0000-0001-5711-6862 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-389056
DOI:	10.1007/s11136-015-1005-8
Journal or Publication Title:	Qual. Life Res.
Volume:	24
Number:	11
Page Range:	S. 2713 - 2723
Date:	2015
Publisher:	SPRINGER
Place of Publication:	DORDRECHT
ISSN:	1573-2649
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language PRIMARY-CARE PATIENTS; BREAST-CANCER; COGNITIVE IMPAIRMENT; RISK-FACTORS; DISABILITY; ILLNESS; WOMEN; ASSOCIATION; PREVALENCE; MORTALITY Multiple languages Health Care Sciences & Services; Health Policy & Services; Public, Environmental & Occupational Health Multiple languages
URI:	http://kups.ub.uni-koeln.de/id/eprint/38905